US Patent:
20040146509, Jul 29, 2004
Inventors:
Zhihe Li - Foster City CA, US
David Liu - Palo Alto CA, US
Jing Ma - Cupertino CA, US
Andrew Protter - Palo Alto CA, US
George Schreiner - Los Altos CA, US
International Classification:
A61K039/395
Abstract:
The invention concerns methods for improvement of lung function by administering non-peptide small molecule inhibitors of TGF- specifically binding to the type I TGF- receptor (TGF-R1). Preferably, the inhibitors are quinazoline derivatives.