Xiaoyin Y He

20130244242, Sep 19, 2013

May 10, 2013

13/891659

Xiaoyin He - Waltham MA, US

Covaris, Inc. - Woburn MA

B01J 19/10
B01F 11/02

435 612, 366108, 422 20, 422128, 435 912, 4351738, 4352891, 4353061, 436501

Methods and systems for acoustically treating material using a continuous process in which material may be caused to flow in a continuous or intermittent fashion into/out of an acoustic treatment chamber where the material is exposed to focused acoustic energy. The methods and systems may be arranged to permit continuous processing for extended periods while an acoustic energy source operates at a relatively high power output. Treatment chambers may include features such as an acoustic window, a heat exchanger, inlet/outlet flow arrangements, an inspection window, insert elements that define a treatment volume size or shape, etc. Treatment system configurations relating to arrangements of a treatment chamber relative to an acoustic source and coupling medium, material flow paths, and others are provided.

20130244285, Sep 19, 2013

May 10, 2013

13/891554

Carl Beckett - Harvard MA, US
Xiaoyin He - Waltham MA, US

Covaris, Inc. - Woburn MA

C12N 13/00
A61L 2/025

435 912, 422128, 422119, 422109, 422 20, 4351735, 4352831, 4352871

Methods and systems for acoustically treating material using a continuous process in which material may be caused to flow in a continuous or intermittent fashion into/out of an acoustic treatment chamber where the material is exposed to focused acoustic energy. The methods and systems may be arranged to permit continuous processing for extended periods while an acoustic energy source operates at a relatively high power output. Treatment chambers may include features such as an acoustic window, a heat exchanger, inlet/outlet flow arrangements, an inspection window, insert elements that define a treatment volume size or shape, etc. Treatment system configurations relating to arrangements of a treatment chamber relative to an acoustic source and coupling medium, material flow paths, and others are provided.

20150161982, Jun 11, 2015

Dec 10, 2013

14/101855

- Woburn MA, US
Xiaoyin He - Waltham MA, US

Covaris, Inc. - Woburn MA

G10K 11/26
G10K 11/28

Methods and systems for acoustically treating material are described. Acoustic energy is emitted into a waveguide having a wall with a shape that tapers away from the acoustic source. The wall may have a substantially conical or parabolic shape. When emitted therein, the waveguide causes convergence of the acoustic energy so as to form an acoustic focal zone at a vessel. In some embodiments, a substantial portion of the acoustic focal zone is located outside of the internal volume defined by the waveguide.

20150079655, Mar 19, 2015

Sep 17, 2013

14/028771

- Woburn MA, US
Xiaoyin He - Waltham MA, US
Srikanth Kakumanu - North Billerica MA, US

Covaris, Inc. - Woburn MA

B01D 43/00
A61L 2/10
C12N 13/00
G01N 1/34
G01N 1/38

4351737, 21074805, 210251, 366108, 4353061, 422 24

Methods and systems for treating material with focused acoustic energy and/or ultraviolet radiation are described. Sample material may be provided to a single batch vessel or may flow in a continuous or intermittent fashion into/out of a processing chamber within which the material is exposed to focused acoustic energy and/or ultraviolet radiation. Exposure to focused acoustics in a flow through environment may enhance the effects of the radiation on the sample material. Further, in flow-through or single batch arrangements, sample material may be retained exterior to or within a processing chamber by one or more retaining members (e.g., filter, valve, etc.) until a characteristic of the sample material reaches one or more particular criteria (e.g., physical, chemical, biological). Once the criteria of the sample material is attained (e.g., via further treatment), the material is then permitted to flow past the retaining member(s) and through the inlet or outlet of the chamber. Further, focused acoustic processing may be used to treat articles, such as the retaining member(s), rather than only sample material located within an internal processing volume of the chamber.

20150056715, Feb 26, 2015

Aug 20, 2014

14/463730

- Woburn MA, US
Xiaoyin He - Waltham MA, US

Covaris, Inc. - Woburn MA

G01N 1/40
B01J 19/10

436175, 422128

Methods and systems for acoustically treating material using an acoustic energy system having a movable outer surface that contacts a sample holder. The outer surface may be cylindrical and rotate about a central axis, e.g., so that a sample holder may be driven to move by the outer surface. Acoustic energy may be emitted from within the outer surface to a treatment area outside of, and near, the outer surface. Thus, a sample holder in contact with the outer surface may have a sample exposed to acoustic energy while rotation of the outer surface may move the sample holder relative to treatment area. One or more additional rollers or other components may bias the sample holder into contact with the outer surface, to e.g., so the sample holder is squeezed between the outer surface and a roller or other biasing component.