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Samuel S Kintz

from Boulder, CO
Age ~39
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Also known as:
Samuel Sebastian Kintz
Related to:
Garth V Kimbrough, 70Saralloyd TruaxPhillip TruaxKevin M Gilbert, 35David G Kintz, 70Susanna T Kintz, 65Rosemary E Kintz, 94Corydon D Kintz, 32David G KintzMatthew W Kintz, 34Katharine Piro Truax, 79Natalie M Kintz, 38Lysbeth C Truax, 65
Connected to:
Anita D Kintz, 66Anne E Kintz, 57Brett W Kintz, 52Carly E Kintz, 38Daniel Kintz, 48Karl A Kintz, 61Soline S Kintz, 52Daniel L Kintzel, 49Geraldine A Kintzel, 71April L Kintzer, 64

Samuel Kintz Phones & Addresses

  • Boulder, CO
  • Seattle, WA
  • 496 Crestlake Dr, San Francisco, CA 94132 (847) 209-3959
  • Palo Alto, CA
  • San Mateo, CA
  • Redwood City, CA
  • Menlo Park, CA
  • Encinitas, CA
  • Lake Forest, IL

Publications

Us Patents

Substituted 6,6-Fused Nitrogenous Heterocyclic Compounds And Uses Thereof

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US Patent:
8623889, Jan 7, 2014
Filed:
Dec 14, 2011
Appl. No.:
13/325751
Inventors:
Joseph P. Lyssikatos - Piedmont CA, US
Lewis J. Gazzard - Belmont CA, US
Emily Hanan - Redwood City CA, US
Samuel Kintz - Redwood City CA, US
Hans Edward Purkey - Burlingame CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
A01N 43/42
A61K 31/44
A61K 31/47
C07D 221/02
C07D 471/02
C07D 217/00
US Classification:
514299, 514307, 514300, 546112, 546139, 546113
Abstract:
The invention provides novel compounds having the general formula:.

Diazacarbazoles And Methods Of Use

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US Patent:
20110118230, May 19, 2011
Filed:
Jun 10, 2009
Appl. No.:
12/997066
Inventors:
Huifen Chen - Burlingame CA, US
Hazel Joan Dyke - Harlow, GB
Charles Ellwood - Essex, GB
Emanuela Gancia - Harlow, GB
Lewis J. Gazzard - Belmont CA, US
Simon Goodacre - Harlow, GB
Samuel Kintz - Redwood City CA, US
Joseph Lyssikatos - Piedmont CA, US
Calum Macleod - Harlow, GB
Karen Williams - Harlow, GB
International Classification:
A61K 31/4375
C07D 471/14
C07D 513/04
C07D 495/04
C07D 491/107
C07D 487/04
A61K 31/496
A61K 31/4545
A61K 31/5377
A61K 31/553
A61K 31/55
A61K 31/541
A61K 31/438
A61K 31/497
A61K 31/501
A61K 31/506
A61K 31/519
A61P 35/00
A61P 35/02
US Classification:
51421016, 546 82, 544361, 544126, 540544, 540597, 546 16, 544 60, 544 582, 544405, 544238, 544333, 544331, 544281, 514293, 51425303, 5142328, 51421021, 51421115, 51421707, 5142285, 514278, 51425505, 51425204, 514256, 514275, 5142591
Abstract:
The invention relates to 1,7-diazacarbazole compounds of Formula (I), (I-a) and (I-b) which are useful as kinase inhibitors, more specifically useful as checkpoint kinase 1 (chk1) inhibitors, thus useful as cancer therapeutics. The invention also relates to compositions, more specifically pharmaceutical compositions comprising these compounds and methods of using the same to treat various forms of cancer and hyperproliferative disorders, as well as methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

Methods Of Use Of Diazacarbazoles For Treating Cancer

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US Patent:
20130261104, Oct 3, 2013
Filed:
May 9, 2013
Appl. No.:
13/890949
Inventors:
Hazel Joan Dyke - Harlow, UK
Charles Ellwood - Harlow, UK
Emanuela Gancia - Harlow, UK
Lewis J. Gazzard - Belmont CA, US
Simon Goodacre - Harlow, UK
Samuel Kintz - Redwood City CA, US
Joseph Lyssikatos - Piedmont CA, US
Calum MacLeod - Harlow, UK
Karen Williams - Harlow, UK
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07D 471/14
A61K 31/496
A61K 31/5377
C07D 513/04
C07D 495/04
A61K 45/06
A61K 31/541
A61K 31/501
A61K 31/506
A61K 31/497
A61K 31/519
A61K 31/4375
C07D 491/107
US Classification:
51421021, 514293, 51425303, 5142328, 51421115, 51421707, 514278, 5142285, 51425204, 514275, 51425505, 5142651
Abstract:
Methods of use of compounds of formula (I) for treating cancer:wherein X, Y, X, R, Rand Rare as defined herein.

5- And 6-Azaindole Compounds For Inhibition Of Bcr-Abl Tyrosine Kinases

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US Patent:
20230130724, Apr 27, 2023
Filed:
Dec 13, 2022
Appl. No.:
18/080641
Inventors:
- Boulder CO, US
Samuel KINTZ - Boulder CO, US
Li REN - Superior CO, US
International Classification:
C07D 471/04
C07D 519/00
Abstract:
The present disclosure relates to compounds and compositions for inhibition of Bcr-Abl tyrosine kinases, methods of preparing said compounds and compositions, and their use in the treatment of various cancers, such as chronic myeloid leukemia (CML).

5- And 6-Azaindole Compounds For Inhibition Of Bcr-Abl Tyrosine Kinases

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US Patent:
20230065635, Mar 2, 2023
Filed:
Oct 4, 2021
Appl. No.:
17/493380
Inventors:
- Boulder CO, US
Samuel KINTZ - Boulder CO, US
Li REN - Superior CO, US
International Classification:
C07D 471/04
C07D 519/00
Abstract:
The present disclosure relates to compounds and compositions for inhibition of Bcr-Abl tyrosine kinases, methods of preparing said compounds and compositions, and their use in the treatment of various cancers, such as chronic myeloid leukemia (CML).

Substituted 6,6-Fused Nitrogenous Heterocyclic Compounds And Uses Thereof

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US Patent:
20160060262, Mar 3, 2016
Filed:
Oct 30, 2015
Appl. No.:
14/928973
Inventors:
- South San Francisco CA, US
Lewis J. Gazzard - Belmont CA, US
Emily Hanan - Redwood City CA, US
Samuel S. Kintz - Stanford CA, US
Hans Edward Purkey - Burlingame CA, US
Assignee:
GENENTECH, INC. - South San Francisco CA
International Classification:
C07D 471/04
C07D 417/04
C07D 401/14
C07D 405/12
C07D 413/12
C07D 217/22
C07D 401/12
Abstract:
The invention provides novel compounds having the general formula:

1,7-Diazacarbazoles And Methods Of Use

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US Patent:
20150328195, Nov 19, 2015
Filed:
Jun 18, 2015
Appl. No.:
14/743835
Inventors:
- South San Francisco CA, US
Lewis Gazzard - South San Francisco CA, US
Karen Williams - Harlow, GB
Huifen Chen - South San Francisco CA, US
Samuel Kintz - South San Francisco CA, US
Joy Drobnick - South San Francisco CA, US
Joseph P. Lyssikatos - South San Francisco CA, US
Simon Goodacre - Harlow, GB
Calum Macleod - Harlow, GB
Charles Ellwood - Harlow, GB
Assignee:
GENENTECH, INC. - South San Francisco CA
International Classification:
A61K 31/4375
C07D 471/14
A61K 31/496
A61K 45/06
C07D 453/02
C07D 519/00
A61K 31/55
A61K 31/5377
A61K 31/439
Abstract:
The invention relates to 1,7-diazacarbazole compounds of Formula (I), (I-a) and (I-b) which are useful as kinase inhibitors, more specifically useful as checkpoint kinase 1 (chk1) inhibitors, thus useful as cancer therapeutics. The invention also relates to compositions, more specifically pharmaceutical compositions comprising these compounds and methods of using the same to treat various forms of cancer and hyperproliferative disorders, as well as methods of using the compounds for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, or associated pathological conditions.

Methods Of Use Of Diazacarbazoles For Treating Cancer

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US Patent:
20150087630, Mar 26, 2015
Filed:
Apr 17, 2014
Appl. No.:
14/255898
Inventors:
- South San Francisco CA, US
Hazel Joan Dyke - Harlow, GB
Charles Ellwood - Harlow, GB
Emanuela Gancia - Harlow, GB
Lewis Gazzard - Belmont CA, US
Simon Goodacre - Harlow, GB
Samuel Kintz - Redwood City CA, US
Joseph Lyssikatos - Piedmont CA, US
Calum MacLeod - Harlow, GB
Karen Williams - Harlow, GB
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07D 471/14
A61K 31/496
A61K 31/5377
A61K 45/06
A61K 31/553
A61K 31/55
A61K 31/541
A61K 31/4375
C07D 519/00
US Classification:
51421021, 514293, 51425303, 5142328, 51421115, 51421707, 5142285
Abstract:
Methods of use of compounds of formula (I) for treating cancer:wherein X, Y, X, R, Rand Rare as defined herein.
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Samuel S Kintz from Boulder, CO, age ~39 Get Report