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Milind M Rajadhyaksha

from New York, NY
Age ~61
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Related to:
Aditi M Rajadhyaksha, 29
Connected to:
Mangirish N Rajadhyaksha, 35Nelly M Rajadhyaksha, 79Rajesh Rajadhyaksha, 64Shyam V Rajadhyaksha, 52Saeid Rajaei, 70Ambika Rajagopalan, 40Anitha M Rajagopalan, 55Anupama Rajagopal, 44Aruna Rajagopal, 50Desikan Rajagopal, 54

Milind Rajadhyaksha Phones & Addresses

  • 430 63Rd St, New York, NY 10021 (646) 414-4888
  • 430 E 63Rd St #3L, New York, NY 10065 (646) 414-4888
  • 1755 York Ave APT 11D, New York, NY 10128
  • 110 Browne St, Brookline, MA 02446 (617) 566-5378
  • Somerville, MA
  • Charlestown, MA
  • West Lafayette, IN

Resumes

Resumes

Milind Rajadhyaksha Photo 1

Member , Department Of Medicine, Dermatology Service

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Location:
New York, NY
Industry:
Hospital & Health Care
Work:
Memorial Sloan-Kettering Cancer Center
Assistant Member
Education:
Purdue University 1985 - 1991
Skills:
Design and Development of Confocal Microcopes
Translational and Clinical Research In Skin and Tissue Imaging
Microscopy
Confocal Microscopy
Milind Rajadhyaksha Photo 2

Milind Rajadhyaksha

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Publications

Us Patents

System And Method For Enhancing Confocal Reflectance Images Of Tissue Specimens

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US Patent:
6720547, Apr 13, 2004
Filed:
Sep 14, 2001
Appl. No.:
09/936535
Inventors:
Milind Rajadhyaksha - Charlestown MA
James M. Zavislan - Pittsford NY
Assignee:
Lucid, Inc. - Rochester NY
The General Hospital Corporation - Boston MA
International Classification:
H01J 4014
US Classification:
250225, 2502081
Abstract:
A confocal scanning microscope system ( ) using cross polarization effects and an enhancement agent (acetic acid) to enhance confocal microscope reflectance images of the nuclei of BCCs (basal cell carcinomas) and SCCs (squamous call carcinomas) in the confocal reflectance images of excised tumor slices. The confocal scanning microscope system having a laser ( ) for generating an illumination beam ( ), a polygon mirror ( ) for scanning the beam to a tissue sample ( ) and for receiving a return beam from the tissue sample and detector ( ) for detecting the returned beam to form an image. The system further includes a half-waveplate ( ) having a rotatable stage ( ) and a quarter-wave plate ( ) having a rotatable stage ( ) disposed in the optical path of the illumination beam and at least a linear polarizer ( ) having a rotatable stage ( ) disposed in the optical path of the returned beam from the tissue sample.

System And Method For Enhancing Confocal Reflectance Images Of Tissue Specimens

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US Patent:
7110114, Sep 19, 2006
Filed:
Feb 26, 2004
Appl. No.:
10/787473
Inventors:
Milind Rajadhyaksha - Charlestown MA, US
James M. Zavislan - Pittsford NY, US
Assignee:
Lucid, Inc. - Rochester NY
The General Hospital Corporation - Boston MA
International Classification:
G01J 4/00
US Classification:
356369, 25055909, 250225
Abstract:
A confocal scanning microscope system () using cross polarization effects and an enhancement agent (acetic acid) to enhance confocal microscope reflectance images of the nuclei of BCCs (basal cell carcinomas) and SCCs (squamous call carcinomas) in the confocal reflectance images of excised tumor slices. The confocal scanning microscope system having a laser () for generating an illumination beam (), a polygon mirror () for scanning the beam to a tissue sample () and for receiving a return beam from the tissue sample and detector () for detecting the returned beam to form an image. The system further includes a half-waveplate () having a rotatable stage () and a quarter-wave plate () having a rotatable stage () disposed in the optical path of the illumination beam and at least a linear polarizer () having a rotatable stage () disposed in the optical pat of the returned beam from the tissue sample.

System And Method For Enhancing Confocal Reflectance Images Of Tissue Specimens

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US Patent:
7515266, Apr 7, 2009
Filed:
Aug 4, 2006
Appl. No.:
11/499582
Inventors:
Milind Rajadhyaksha - Charlestown MA, US
James M. Zavislan - Pittsford NY, US
Assignee:
Lucid, Inc. - Rochester NY
The General Hospital Corporation - Boston MA
International Classification:
G01J 4/00
US Classification:
356369
Abstract:
A confocal scanning microscope system () using cross polarization effects and an enhancement agent (acetic acid) to enhance confocal microscope reflectance images of the nuclei of BCCs (basal cell carcinomas) and SCCs (squamous cell carcinomas) in the confocal reflectance images of excised tumor slices. The confocal scanning microscope system having a laser () for generating an illumination beam (), a polygon mirror () for scanning the beam to a tissue sample () and for receiving a returned beam from the tissue sample and detector () for detecting the returned beam to form an image. The system further includes a half-wave plate () having a rotatable stage () and a quarter-wave plate () having a rotatable stage () disposed in the optical path of the illumination beam and at least a linear polarizer () having a rotatable stage () disposed in the optical path of the returned beam from the tissue sample.

System And Method For Macroscopic And Confocal Imaging Of Tissue

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US Patent:
20040133112, Jul 8, 2004
Filed:
Feb 23, 2004
Appl. No.:
10/471332
Inventors:
Milind Rajadhyaksha - Brookline MA, US
International Classification:
A61B006/00
US Classification:
600/476000
Abstract:
A system and method for imaging tissue samples is provided having a confocal microscope integrated with the confocal microscope. Such tissue samples may represent excised tissue from Moh's micrographic surgery. The system enables a user, such as a Moh's surgeon, to examine the low-resolution image of the tissue sample provided by the macroscope and identity sites that potentially appear to be abnormal, and then further examine the nuclear morphology of tissue at such sites in high-resolution images from the confocal microscope to detect the presence of abnormal tissue structures (cells), such as cancer. One or more agents such as acetic acid and calcein AM may be applied to the tissue sample to enhance the contrast of tissue structures in confocal and/or macroscopic images. Optics may be provided to enable the system to operate the macroscopic and confocal microscope in reflectance or fluorescence imaging modes.

Apparatus, System And Method For Providing Laser Steering And Focusing For Incision, Excision And Ablation Of Tissue In Minimally-Invasive Surgery

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US Patent:
20120302828, Nov 29, 2012
Filed:
Mar 14, 2012
Appl. No.:
13/420340
Inventors:
Snehal Patel - New York NY, US
Milind Rajadhyaksha - New York NY, US
Assignee:
MEMORIAL SLOAN KETTERING CANCER CENTER - New York NY
International Classification:
A61N 5/067
A61B 1/07
US Classification:
600108
Abstract:
Exemplary embodiments of apparatus, system, computer-accessible medium, procedure and method are provided which can be used for providing laser steering and focusing for, e.g., incision, excision and/or ablation of tissue in minimally-invasive surgery. For example, the exemplary apparatus can include at least one optical element which can be configured to refract and/or diffract light provided in a structure which can be configured to be inserted into a body, where at least one of the optical element(s) is structured to receive the light at a first angle and generate a refracted and/or diffracted light at a second angle which can be different from the first angle relative to an optical axis. For example, an actuating arrangement can be provided, which can be configured to control the optical element(s), can be provided and situated at least partially within the at least one structure.

System, Device, Method And Computer Accessible Medium For Imaging Large Areas With Microscopic Resolution

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US Patent:
20130266980, Oct 10, 2013
Filed:
Apr 4, 2013
Appl. No.:
13/856672
Inventors:
Yongbiao Li - Dobbs Ferry NY, US
Bjorg Larson - Brookhlyn NY, US
Milind Rajadhyaksha - New York NY, US
Assignee:
Memorial Sloan-Kettering Cancer Center - New York NY
International Classification:
G01N 33/50
US Classification:
435 34, 4352887
Abstract:
Exemplary systems, method and non-transitory computer-accessible medium can be provided for generating an image of at least one tissue that can be subdivided into a plurality of strips. Using such exemplary systems, method and computer-accessible medium, it is possible to scan, using an optical arrangement to generate first information, a first portion of the tissue(s) along a first one of the strips while the tissue(s) can be mechanically moved in a first direction. Move the one tissue(s), by a distance equal to or less than a width of the first portion, in a second direction approximately perpendicular to the first direction. Use the optical arrangement to generate second information, a second portion of the tissue(s) along a second one of the strips while the tissue(s) can be mechanically moved in a third direction, which can be approximately opposite to the first direction. Then the image can be generated based on the first information and the second information.

Three-Dimensional Scanning Confocal Laser Microscope

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US Patent:
59952830, Nov 30, 1999
Filed:
Nov 12, 1998
Appl. No.:
9/190689
Inventors:
R. Rox Anderson - Lexington MA
Robert H. Webb - Lincoln MA
Milind Rajadhyaksha - Charlestown MA
Assignee:
General Hospital Corporation - Boston MA
International Classification:
G02B 2106
G02B 2608
US Classification:
359385
Abstract:
A confocal microscope for generating an image of a sample includes a first scanning element for scanning a light beam along a first axis, and a second scanning element for scanning the light beam at a predetermined amplitude along a second axis perpendicular to the first axis. A third scanning element scans the light beam at a predetermined amplitude along a third axis perpendicular to an imaging plane defined by the first and second axes. The second and third scanning element are synchronized to scan at the same frequency. The second and third predetermined amplitudes are percentages of their maximum amplitudes. A selector determines the second and third predetermined amplitudes such that the sum of the percentages is equal to one-hundred percent.

Three-Dimensional Scanning Confocal Laser Microscope

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US Patent:
58808809, Mar 9, 1999
Filed:
Jul 15, 1996
Appl. No.:
8/683607
Inventors:
R. Rox Anderson - Lexington MA
Robert H. Webb - Lincoln MA
Milind Rajadhyaksha - Charlestown MA
Assignee:
The General Hospital Corp. - Boston MA
International Classification:
G02B 2106
US Classification:
359385
Abstract:
A confocal microscope for generating an image of a sample includes a first scanning element for scanning a light beam along a first axis, and a second scanning element for scanning the light beam at a predetermined amplitude along a second axis perpendicular to the first axis. A third scanning element scans the light beam at a predetermined amplitude along a third axis perpendicular to an imaging plane defined by the first and second axes. The second and third scanning element are synchronized to scan at the same frequency. The second and third predetermined amplitudes are percentages of their maximum amplitudes. A selector determines the second and third predetermined amplitudes such that the sum of the percentages is equal to one-hundred percent.
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Milind M Rajadhyaksha from New York, NY, age ~61 Get Report