Search

Mark J Zylka

from Chapel Hill, NC
Age ~52
Get Report
Also known as:
Mark John Zylka, John L Zylka
Phone and address:
120 Della St, Chapel Hill, NC 27516
(919) 360-5898
Related to:
Matthew CumminsJames G Fields, 66
Connected to:
Deborah J Zylka, 66Edward J Zylka, 65Lawrence C Zylka, 81Mary B Zylka, 68Tai B Zylka, 40Cheryl K Zylla, 65Daniel G Zylla, 66Emily B Zylla, 45Brad A Zylman, 58Mary E Zylo, 91

Mark Zylka Phones & Addresses

  • 120 Della St, Chapel Hill, NC 27516 (919) 360-5898
  • Carrboro, NC
  • Durham, NC
  • 1156 Steuben St, Pasadena, CA 91106
  • Sykesville, MD
  • Boston, MA
  • Blacksburg, VA
  • Littlestown, PA
  • 120 Della St, Chapel Hill, NC 27516

Work

Company: University of north carolina at chapel hill 2006 Position: Professor

Education

Degree: Doctorates, Doctor of Philosophy School / High School: Harvard University 1996 to 1999

Skills

Molecular Biology • Cell Biology • Biochemistry • Animal Models • Confocal Microscopy • Neuroscience • Cell Culture • Immunohistochemistry • Genetics • Fluorescence Microscopy • Translational Research • Western Blotting • Microscopy • Molecular Cloning • Protein Chemistry • Cell • Immunofluorescence • Protein Purification • Tissue Culture • In Vitro • In Vivo • Genomics • Transfection

Industries

Biotechnology

Resumes

Resumes

Mark Zylka Photo 1

Professor

View page
Location:
120 Della St, Chapel Hill, NC 27516
Industry:
Biotechnology
Work:
University of North Carolina at Chapel Hill
Professor
Caltech 1999 - 2005
Postdoc
Education:
Harvard University 1996 - 1999
Doctorates, Doctor of Philosophy Virginia Tech 1990 - 1994
Bachelors, Bachelor of Science, Biochemistry
Skills:
Molecular Biology
Cell Biology
Biochemistry
Animal Models
Confocal Microscopy
Neuroscience
Cell Culture
Immunohistochemistry
Genetics
Fluorescence Microscopy
Translational Research
Western Blotting
Microscopy
Molecular Cloning
Protein Chemistry
Cell
Immunofluorescence
Protein Purification
Tissue Culture
In Vitro
In Vivo
Genomics
Transfection

Publications

Us Patents

Assay Employing G Protein-Coupled Receptor Expressed In Dorsal Root Ganglia

View page
US Patent:
7510845, Mar 31, 2009
Filed:
Mar 17, 2005
Appl. No.:
11/083611
Inventors:
David J. Anderson - Altadena CA, US
Xinzhong Dong - Pasadena CA, US
Mark J. Zylka - Pasadena CA, US
Melvin I. Simon - La Jolla CA, US
Assignee:
California Institute of Technology - Pasadena CA
International Classification:
G01N 33/566
C07K 14/705
US Classification:
435 72, 435 721, 436501
Abstract:
The invention relates generally to novel genes expressed in normal but not Neurogenin-1-deficient animals. The invention relates specifically to a novel family of G protein-coupled receptors and a novel family of two-transmembrane segment proteins that are expressed in dorsal root ganglia, and a method of screening for genes specifically expressed in nociceptive sensory neurons.

Methods For Identifying Compounds Which Modulate Circadian Rhythm

View page
US Patent:
20030059848, Mar 27, 2003
Filed:
Sep 17, 2002
Appl. No.:
10/245175
Inventors:
Steven Reppert - Newton MA, US
David Weaver - Londonderry NH, US
Mark Zylka - Pasadena CA, US
Xiaowei Jin - Boston MA, US
Kazuhiko Kume - Belmont MA, US
Sriram Sathyanarayanan - Somerville MA, US
Lauren Shearman - Jamaica Plain MA, US
Assignee:
The General Hospital Corporation, a Massachusetts corporation
International Classification:
G01N033/53
US Classification:
435/007100
Abstract:
The invention is based, in part, on the discovery that the CRY proteins and the PER2 protein function as important modulators of mammalian circadian rhythm. The invention includes methods of modulating the circadian rhythm and identifying compounds that modulate the circadian rhythm.

Pain Signaling Molecules

View page
US Patent:
20030092035, May 15, 2003
Filed:
Jun 26, 2002
Appl. No.:
10/183116
Inventors:
David Anderson - Altadena CA, US
Xinzhong Dong - Pasadena CA, US
Mark Zylka - Pasadena CA, US
Melvin Simon - San Marino CA, US
International Classification:
C12Q001/68
C07H021/04
C12P021/02
C12N005/06
C07K014/705
US Classification:
435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:
The invention relates generally to novel genes expressed in normal but not Neurogenin-1-deficient animals. The invention relates specifically to a novel family of G protein-coupled receptors and a novel family of two-transmembrane segment proteins that are expressed in dorsal root ganglia, and a method of screening for genes specifically expressed in nociceptive sensory neurons.

Pain Signaling Molecules

View page
US Patent:
20040121410, Jun 24, 2004
Filed:
Dec 20, 2002
Appl. No.:
10/327387
Inventors:
David Anderson - Altadena CA, US
Xinzhong Dong - Pasadena CA, US
Mark Zylka - Pasadena CA, US
Melvin Simon - Pasadena CA, US
International Classification:
G01N033/53
G01N033/567
A61K039/395
US Classification:
435/007200, 424/146100
Abstract:
A novel G protein-coupled receptor called MrgC11 has been identified that is expressed in dorsal root ganglia and that is activated by RF amide related peptides.

Pain Signaling Molecules

View page
US Patent:
20050037468, Feb 17, 2005
Filed:
Sep 30, 2004
Appl. No.:
10/957135
Inventors:
David Anderson - Altadena CA, US
Xinzhong Dong - Pasadena CA, US
Mark Zylka - Pasadena CA, US
Melvin Simon - San Marino CA, US
International Classification:
C07K014/705
US Classification:
435069100, 435320100, 435325000, 530350000, 536023500, 435252330, 435254200
Abstract:
The invention relates generally to novel genes expressed in normal but not Neurogenin-1-deficient animals. The invention relates specifically to a novel family of G protein-coupled receptors and a novel family of two-transmembrane segment proteins that are expressed in dorsal root ganglia, and a method of screening for genes specifically expressed in nociceptive sensory neurons.

Identification Of A Receptor Controlling Migration And Metastasis Of Skin Cancer Cells

View page
US Patent:
20050196757, Sep 8, 2005
Filed:
Jun 19, 2003
Appl. No.:
10/601305
Inventors:
Mark Zylka - Pasadena CA, US
Xinzhong Dong - Pasadena CA, US
David Anderson - Altadena CA, US
International Classification:
C12Q001/68
G01N033/574
US Classification:
435006000, 435007230
Abstract:
The invention relates generally to genes expressed in skin cancer cells, particularly melanoma tumor cells, and their role in migration and metastasis. Methods for identifying melanoma cells are provided, as are methods of treating melanoma. Methods for identifying compounds that are useful in the treatment of melanoma are also provided.

Pain Signaling Molecules

View page
US Patent:
20050208047, Sep 22, 2005
Filed:
Apr 27, 2005
Appl. No.:
11/117746
Inventors:
David Anderson - Altadena CA, US
Xinzhong Dong - Pasadena CA, US
Mark Zylka - Pasadena CA, US
Melvin Simon - Pasadena CA, US
International Classification:
C12Q001/68
C07H021/04
A61K039/395
C12N015/09
C07K014/705
US Classification:
424143100, 435006000, 435320100, 435069100, 435325000, 530350000, 536023500
Abstract:
A novel G protein-coupled receptor called MrgC11 has been identified that is expressed in dorsal root ganglia and that is activated by RF amide related peptides.

Pain Signaling Molecules

View page
US Patent:
20070196873, Aug 23, 2007
Filed:
Feb 5, 2007
Appl. No.:
11/703062
Inventors:
David Anderson - Altadena CA, US
Xinzhong Dong - Pasadena CA, US
Mark Zylka - Pasadena CA, US
Melvin Simon - San Mario CA, US
International Classification:
G01N 33/567
US Classification:
435007200
Abstract:
The invention relates generally to novel genes expressed in normal but not Neurogenin-1-deficient animals. The invention relates specifically to a novel family of G protein-coupled receptors and a novel family of two-transmembrane segment proteins that are expressed in dorsal root ganglia, and a method of screening for genes specifically expressed in nociceptive sensory neurons.
Control profile
Mark J Zylka from Chapel Hill, NC, age ~52 Get Report