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Mariena Vivian Mattson

from North Potomac, MD
Age ~67
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Also known as:
Mariena V Mattson, Marina V Mattson
Phone and address:
11619 Parsippany Ter, Gaithersburg, MD 20878
(301) 424-5414
Related to:
Mark MattsonRonald J Inscoe, 63Sharon R Hunt, 61Betty M MattsonLyle C Mattson, 68Jim G MattsonHeidi S Harrill, 41William R Benthall, 69
Connected to:
Alex Mattson, 43Antoinette MattsonAutumn L Mattson, 47Barry L Mattson, 45Blake C Mattson, 56Bryce E Mattson, 28Caroline C Mattson, 95Colby D Mattson, 71Crystal Mattson, 40Danica J Mattson, 44

Mariena Mattson Phones & Addresses

  • 11619 Parsippany Ter, Gaithersburg, MD 20878 (301) 424-5414
  • North Potomac, MD
  • 3600 Kenway St, Silver Spring, MD 20906
  • Rockville, MD

Publications

Us Patents

5-Aminocarbonyl-5H-Dibenzo[A.d]Cyclohepten-5,10-Imines For Treatment Of Epilepsy And Cocaine Addiction

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US Patent:
51964155, Mar 23, 1993
Filed:
Jan 29, 1992
Appl. No.:
7/827383
Inventors:
James A. Monn - Gaithersburg MD
Andrew Thurkauf - Crofton MD
Shunichi Yamaguchi - Bethesda MD
Michael A. Rogawski - Columbia MD
Kenner C. Rice - Bethesda MD
Mariena V. Mattson - Rockville MD
Arthur E. Jacobson - Potomac MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C07D22122
C07D22310
A61K 3144
A61K 3155
US Classification:
514210
Abstract:
This invention is in the field of clinical neurology and relates specifically to compounds, compositions and methods for treatment of patients with generalized epilepsy or partial (symptomatic) epilepsy using compounds of the formula: ##STR1## This invention also relates to compounds, compositions and methods of treatment for drug craving in patients addicted to cocaine.

Metaphit, A Specific Acylating Agent For The [.Sup.3 H] Phencyclidine

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US Patent:
45981531, Jul 1, 1986
Filed:
Dec 19, 1984
Appl. No.:
6/683428
Inventors:
Kenner C. Rice - Rockville MD
Michael F. Rafferty - Ann Arbor MI
Arthur E. Jacobson - Potomac MD
Patricia Contreras - Bethesda MD
Thomas L. O'Donohue - Silver Spring MD
Ralph A. Lessor - Bethesda MD
Mariena V. Mattson - Wheaton MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C07D29512
US Classification:
546229
Abstract:
A derivative of phencyclidine (1) bearing an isothiocyanate moiety of the meta position of the aromatic ring (2; Metaphit) has been synthesized and identified as a rapid and specific site-directed acylating agent of the [. sup. 3 H]-phencyclidine binding site in rat brain homogenates.

Metaphit And Related Compounds As Acylating Agents For The (3H)Phencyclidine Receptors

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US Patent:
47628464, Aug 9, 1988
Filed:
Jan 31, 1986
Appl. No.:
6/824848
Inventors:
Kenner C. Rice - Rockville MD
Michael F. Rafferty - Ann Arbor MI
Arthur E. Jacobson - Potomac MD
Patricia Contreras - Bethesda MD
Thomas L. O'Donohue - Silver Spring MD
Ralph A. Lessor - Bethesda MD
Mariena V. Mattson - Wheaton MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
C07D21128
A61K 3126
A61K 31445
US Classification:
514331
Abstract:
A derivative of phencyclidine (1) bearing an isothiocyanate moiety on the meta position of the aromatic ring (3; Metaphit as methanesulfonate and HCl salt) has been synthesized and identified as a rapid and specific site-directed acylating agent of the [. sup. 3 H]-phencyclidine binding site in rat brain homogenates. Additional related compounds to Metaphit are Thiophit (oxalate salt), Ethylphit (HCl salt), and Isopropylphit (HCl salt).

N-(1-Thienylcycloalkyl)Alkenylamines For Treatment Of Neurotoxic Injury

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US Patent:
54017556, Mar 28, 1995
Filed:
Oct 8, 1991
Appl. No.:
7/774003
Inventors:
Kenner C. Rice - Rockville MD
Arthur E. Jacobson - Potomac MD
Andrew Thurkauf - Laurel MD
Mariena V. Mattson - Rockville MD
Thomas L. O'Donohue - Chesterfield MO
Patricia C. Contreras - Ballwin MO
Nancy M. Gray - Ellisville MO
Assignee:
G. D. Searle & Co. - Skokie IL
National Institutes of Health - Rockville MD
International Classification:
C07D40908
A61K 3144
US Classification:
514336
Abstract:
Compounds, compositions and methods of treatment are described to control brain damage associated with anoxia or ischemia which typically follows stroke, cardiac arrest or perinatal asphyxia. The treatment includes administration of an N-(1-thienylcycloalkyl)alkenylamine compound as an antagonist to inhibit excitotoxic actions at major neuronal excitatory amino acid receptor sites. Compounds of most interest are those of the formula ##STR1## wherein R. sup. 1, R. sup. 2, and R. sup. 5 are defined in specification.

N-(1-Thienylcycloalkyl)Alkenylamines For Treatment Of Neurotoxic Injury

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US Patent:
56042558, Feb 18, 1997
Filed:
Nov 23, 1994
Appl. No.:
8/344433
Inventors:
Kenner C. Rice - Rockville MD
Arthur E. Jacobson - Potomac MD
Andrew Thurkauf - Laurel MD
Mariena V. Mattson - Rockville MD
Thomas L. O'Donohue - Chesterfield MO
Patricia C. Contreras - Ballwin MO
Nancy M. Gray - Ellisville MO
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
G. D. Searle & Co. - Skokie IL
International Classification:
C07D40904
A61K 3140
US Classification:
514422
Abstract:
Compounds, compositions and methods of treatment are described to control brain damage associated with anoxia or ischemia which typically follows stroke, cardiac arrest or perinatal asphyxia. The treatment includes administration of an N-(1-thienylcycloalkyl)alkenylamine compound as an antagonist to inhibit excitotoxic actions at major neuronal excitatory amino acid receptor sites. Compounds of most interest are those of the formula ##STR1## wherein R. sup. 1 is one or more groups selected from hydrido, alkyl of one to about five carbon atoms, cycloalkyl of three to about five carbon atoms, alkenyl of two to about five carbon atoms, hydroxyl and alkoxy; wherein each of R. sup. 2 is one or more groups selected from hydrido, alkyl of one to about five carbon atoms, cycloalkyl of three to about five carbon atoms, alkenyl of two to about five carbon atoms, hydroxyl, oxo and alkoxy; wherein R. sup. 5 is one or more groups selected from hydrido, alkyl of one to about five carbon atoms, cycloalkyl of three to about five carbon atoms, alkenyl of two to about five carbon atoms, hydroxyl and alkoxy; and wherein the broken line within the N-containing ring represents a double bond between any two adjacent carbon atoms.
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Mariena Vivian Mattson from North Potomac, MD, age ~67 Get Report