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Lianhong Xu

from Palo Alto, CA
Age ~59

Lianhong Xu Phones & Addresses

  • 970 Blair Ct, Palo Alto, CA 94303
  • Lancaster, CA
  • 640 Hobart Ave, San Mateo, CA 94402 (650) 372-9271
  • Foster City, CA
  • Libertyville, IL
  • Houston, TX
  • Los Angeles, CA
  • Park City, IL

Publications

Us Patents

Non Nucleoside Reverse Transcriptase Inhibitors

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US Patent:
7462608, Dec 9, 2008
Filed:
Apr 25, 2003
Appl. No.:
10/424130
Inventors:
James M. Chen - San Ramon CA, US
Xiaowu Chen - San Mateo CA, US
Choung U. Kim - San Carlos CA, US
William A. Lee - Los Altos CA, US
Christopher P. Lee - San Francisco CA, US
Peter H. Nelson - Los Altos CA, US
James D. Tario - San Mateo CA, US
Lianhong Xu - San Mateo CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/665
C07D 265/18
US Classification:
514 75, 544 90
Abstract:
Phosphorus-substituted imidazole compounds with anti-HIV properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit reverse transcriptase activity and are useful therapeutically for the inhibition of such enzymes, as well as in assays for the detection of such enzymes.

Cellular Accumulation Of Phosphonate Analogs Of Hiv Protease Inhibitor Compounds

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US Patent:
7649015, Jan 19, 2010
Filed:
Apr 25, 2003
Appl. No.:
10/423496
Inventors:
Xiaowu Chen - San Mateo CA, US
Maria Fardis - San Carlos CA, US
Gong-Xin He - Fremont CA, US
Haolun Jin - Foster City CA, US
Choung U. Kim - San Carlos CA, US
William A. Lee - Los Altos CA, US
Kuei-Ying Lin - Fremont CA, US
Hongtao Liu - Foster City CA, US
Richard L. Mackman - Millbrae CA, US
Michael L. Mitchell - Foster City CA, US
Hyung-Jung Pyun - Fremont CA, US
Mark Sparacino - Morgan Hill CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
Jianying Wang - Foster City CA, US
Matthew A. Williams - San Mateo CA, US
Lianhong Xu - San Mateo CA, US
Zheng-Yu Yang - Foster City CA, US
Richard H. Yu - San Francisco CA, US
Jiancun Zhang - Oakland CA, US
Lijun Zhang - Foster City CA, US
Assignee:
Gilead Sciences, Inc. - Palo Alto CA
International Classification:
A61K 31/343
C07F 9/28
US Classification:
514470, 549220
Abstract:
Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.

Antiviral Protease Inhibitors

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US Patent:
7723380, May 25, 2010
Filed:
Jul 19, 2007
Appl. No.:
11/880069
Inventors:
Carina E. Cannizzaro - Foster City CA, US
James M. Chen - San Ramon CA, US
Manoj C. Desai - Pleasant Hill CA, US
Michael L. Mitchell - Hayward CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
Lianhong Xu - Palo Alto CA, US
Zheng-Yu Yang - Palo Alto CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/343
A61K 31/443
A61K 31/427
A61K 31/41
A61K 31/4196
C07D 493/02
C07D 277/30
C07D 249/08
C07D 215/38
C07D 257/04
C07D 239/02
US Classification:
514469, 514336, 514461, 514365, 514256, 514382, 514383, 544315, 544225, 5462817, 5462841, 548250, 548202, 5482622
Abstract:
The invention is related to compounds of Formula I:.

Aza-Peptide Protease Inhibitors

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US Patent:
7741345, Jun 22, 2010
Filed:
Jul 19, 2007
Appl. No.:
11/880067
Inventors:
Carina E. Cannizzaro - Foster City CA, US
James M. Chen - San Ramon CA, US
Manoj C. Desai - Pleasant Hill CA, US
Michael L. Mitchell - Hayward CA, US
Sundaramoorthi Swaminathan - Burlingame CA, US
Lianhong Xu - Palo Alto CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/4427
A61K 31/443
C07D 405/02
US Classification:
514338, 5462837, 5462841
Abstract:
The invention is related to compounds of Formula I:.

Modulators Of Pharmacokinetic Properties Of Therapeutics

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US Patent:
7939553, May 10, 2011
Filed:
Jul 6, 2007
Appl. No.:
11/825605
Inventors:
Manoj C. Desai - Pleasant Hill CA, US
Allen Yu Hong - San Jose CA, US
Hongtao Liu - Cupertino CA, US
Randall W. Vivian - San Mateo CA, US
Lianhong Xu - Palo Alto CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/426
C07D 277/20
US Classification:
514365, 548204
Abstract:
The present application provides for a compound of Formula I,.

Modulators Of Pharmacokinetic Properties Of Therapeutics

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US Patent:
8067449, Nov 29, 2011
Filed:
Jul 6, 2007
Appl. No.:
12/306198
Inventors:
Manoj C. Desai - Pleasant Hill CA, US
Allen Y. Hong - Pasadena CA, US
Hongtao Liu - Cupertino CA, US
Randall W. Vivian - San Mateo CA, US
Lianhong Xu - Palo Alto CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/426
C07D 277/24
US Classification:
514365, 548204
Abstract:
The present application provides for a compound of Formula I, or a pharmaceutically acceptable salt, solvate, and/or ester thereof, compositions containing such compounds, therapeutic methods that include the administration of such compounds, and therapeutic methods and include the administration of such compounds with at least one additional therapeutic agent.

Antiviral Compounds

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US Patent:
8088368, Jan 3, 2012
Filed:
May 12, 2010
Appl. No.:
12/779023
Inventors:
Hongyan Guo - Foster City CA, US
Darryl Kato - Foster City CA, US
Thorsten A. Kirschberg - Foster City CA, US
Hongtao Liu - Foster City CA, US
John O. Link - Foster City CA, US
Michael L. Mitchell - Foster City CA, US
Jay P. Parrish - Foster City CA, US
Jianyu Sun - Foster City CA, US
James Taylor - Foster City CA, US
Elizabeth M. Bacon - Foster City CA, US
Eda Canales - Foster City CA, US
Aesop Cho - Foster City CA, US
Choung U. Kim - Foster City CA, US
Jeromy J. Cottell - Foster City CA, US
Manoj C. Desai - Foster City CA, US
Randall L. Halcomb - Foster City CA, US
Scott E. Lazerwith - Foster City CA, US
Richard L. Mackman - Foster City CA, US
Hyung-Jung Pyun - Foster City CA, US
Joseph H. Saugier - Foster City CA, US
James D. Trenkle - Foster City CA, US
Winston C. Tse - Foster City CA, US
William J. Watkins - Foster City CA, US
Lianhong Xu - Foster City CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/4178
A61K 31/435
A61K 31/55
A61K 31/438
A61K 31/496
A61K 31/5415
A61K 31/708
A61K 31/7052
A61K 38/21
C07D 403/14
C07D 401/14
C07D 417/14
A61P 31/14
US Classification:
424 854, 424 857, 514217, 5142258, 51425405, 514278, 514299, 514397, 514 43, 544370, 544 35, 546112, 546 16, 5483131, 540587
Abstract:
The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

Modulators Of Pharmacokinetic Properties Of Therapeutics

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US Patent:
8088770, Jan 3, 2012
Filed:
Jul 3, 2008
Appl. No.:
12/217496
Inventors:
Manoj C. Desai - Pleasant Hill CA, US
Hon C. Hui - San Mateo CA, US
Hongtao Liu - Cupertino CA, US
Jianyu Sun - San Mateo CA, US
Lianhong Xu - Palo Alto CA, US
Assignee:
Gilead Sciences, Inc. - Foster City CA
International Classification:
A61K 31/5355
A61K 31/4985
A61K 31/437
A61K 31/4402
A61K 31/426
C07D 417/04
C07D 487/04
C07D 277/24
US Classification:
5142368, 514249, 514303, 514342, 514365, 544133, 544236, 546118, 5462697, 548181, 548204
Abstract:
The present application provides for a compound of Formula IV:.
Lianhong Xu from Palo Alto, CA, age ~59 Get Report