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John Wityak Phones & Addresses

  • Tucson, AZ
  • 3377 Avenida Nieve, Carlsbad, CA 92009 (760) 634-2936
  • 25 Jared Dr, Trenton, NJ 08691 (609) 448-7625
  • Robbinsville, NJ
  • West Grove, PA
  • Corvallis, OR
  • Cupertino, CA
  • Newark, DE
  • San Diego, CA

Work

Position: Medical Professional

Education

Degree: Graduate or professional degree

Publications

Us Patents

Integrin Receptor Antagonists

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US Patent:
6358976, Mar 19, 2002
Filed:
Feb 22, 2000
Appl. No.:
09/510379
Inventors:
John Wityak - West Grove PA, 19390
Aleksandra Ewa Tobin - Lincoln University PA, 19352
International Classification:
A61K 3147
US Classification:
514312, 514 63, 514 80, 514 81, 514183, 51421704, 51421707, 514218, 514274, 514275, 514300, 514303, 540542, 540553, 540554, 540575, 540597, 540599, 544229, 544243, 544318, 544331, 544332, 546 23, 546118, 546122, 546123, 546156, 546 14
Abstract:
This invention relates to novel fused heterocycles which are useful as antagonists of the and related integrin receptors, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of cell adhesion, the treatment of angiogenic disorders, inflammation, bone degradation, cancer metastasis, diabetic retinopathy, thrombosis, restenosis, macular degeneration, and other conditions mediated by cell adhesion and/or cell migration and/or angiogenesis.

Isoxazoline Fibrinogen Receptor Antagonists

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US Patent:
6455560, Sep 24, 2002
Filed:
Jul 13, 2001
Appl. No.:
09/905417
Inventors:
John Wityak - Robbinsville NJ, 08691
Prabhakar K. Jadhav - Wilmington DE, 19807
International Classification:
A61K 3142
US Classification:
514378, 5142368, 514326, 514340, 546229, 546239, 548240
Abstract:
This invention relates to novel isoxazolines of formula (I): or a pharmaceutically acceptable salt form thereof. This invention also relates to novel isoxazolines of formula (I) which are useful as antagonists of the platelet glycoprotein IIb/IIIa fibrinogen receptor complex, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of platelet aggregation, as thrombolytics, and/or for the treatment of thromboembolic disorders.

Cyclic Protein Tyrosine Kinase Inhibitors

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US Patent:
6596746, Jul 22, 2003
Filed:
Apr 13, 2000
Appl. No.:
09/548929
Inventors:
Jagabandhu Das - Mercerville NJ
Ramesh Padmanabha - Hamden CT
Ping Chen - Belle Mead NJ
Derek J. Norris - Trenton NJ
Arthur M. P. Doweyko - Long Valley NJ
Joel C. Barrish - Holland PA
John Wityak - Robbinsville NJ
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C07D27742
US Classification:
514370, 548194
Abstract:
Novel cyclic compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic and oncologic disorders.

Tetrahydroisoquinoline Analogs As Modulators Of Chemokine Receptor Activity

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US Patent:
6649606, Nov 18, 2003
Filed:
Nov 7, 2002
Appl. No.:
10/289671
Inventors:
Mark Alden Hermsmeier - Somerville NJ
David B. Rawlins - Morrisville PA
John Wityak - Robbinsville NJ
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
International Classification:
C07D20902
US Classification:
51421701, 514307, 514412, 540594, 546139, 548492
Abstract:
Tetrahydroisoquinoline analogs are provided which are modulators of chemokine receptor activity. The tetrahdroisoquinoline analogs thereof have the structure wherein R , R , R , R , X , X , X , X , m, n and p are as described herein.

Thiazolyl Inhibitors Of Tec Family Tyrosine Kinases

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US Patent:
6706717, Mar 16, 2004
Filed:
Dec 20, 2001
Appl. No.:
10/027982
Inventors:
Joel C. Barrish - Richboro PA
Jagabandhu Das - Mercerville NJ
Steven B. Kanner - Princeton NJ
Chunjian Liu - Pennington NJ
Steven H. Spergel - Warrington PA
John Wityak - Robbinsville NJ
Arthur M. P. Doweyko - Long Valley NJ
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31496
US Classification:
51425402, 544369
Abstract:
Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.

Benzothiazole Protein Trosine Kinase Inhibitors

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US Patent:
6825355, Nov 30, 2004
Filed:
Oct 26, 2001
Appl. No.:
10/032609
Inventors:
Jagabandhu Das - Mercerville NJ
Joel C. Barrish - Holland PA
John Wityak - Robbinsville NJ
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
International Classification:
C07D27768
US Classification:
548161, 548164
Abstract:
Novel benzothiazoles and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of protein tyrosine kinase-associated disorders such as immunologic disorders.

Thiazolyl Inhibitors Of Tec Family Tyrosine Kinases

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US Patent:
6953795, Oct 11, 2005
Filed:
Aug 15, 2003
Appl. No.:
10/642040
Inventors:
Joel C. Barrish - Richboro PA, US
Jagabandhu Das - Mercerville NJ, US
Steven B. Kanner - Princeton NJ, US
Chunjian Liu - Pennington NJ, US
Steven H. Spergel - Warrington PA, US
John Wityak - Robbinsville NJ, US
Arthur M. P. Doweyko - Long Valley NJ, US
Joseph A. Furch III - Lawrenceville NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K031/5377
C07D419/10
C07D419/12
US Classification:
5142368, 544133
Abstract:
Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.

Thiazolyl Inhibitors Of Tec Family Tyrosine Kinases

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US Patent:
6956045, Oct 18, 2005
Filed:
Aug 15, 2003
Appl. No.:
10/641876
Inventors:
Joel C. Barrish - Richboro PA, US
Jagabandhu Das - Mercerville NJ, US
Steven B. Kanner - Princeton NJ, US
Chunjian Liu - Pennington NJ, US
Steven H. Spergel - Warrington PA, US
John Wityak - Robbinsville NJ, US
Arthur M. P. Doweyko - Long Valley NJ, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K031/454
C07D417/10
C07D417/12
US Classification:
514326, 546209
Abstract:
Novel thiazolyl compounds and salts thereof, pharmaceutical compositions containing such compounds, and methods of using such compounds in the treatment of Tec family tyrosine kinase-associated disorders such as cancer, immunologic disorders and allergic disorders.
John Shari Wityak from Tucson, AZ, age ~66 Get Report