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Jayanta Bhattacharyya Phones & Addresses

  • Raleigh, NC
  • 2021 Spenwick Dr, Houston, TX 77055 (713) 461-3165
  • 2021 Spenwick Dr APT 510, Houston, TX 77055 (713) 461-3165
  • 7611 Jalna St, Houston, TX 77055 (713) 290-8436
  • Hilshire Village, TX
  • Littleton, CO
  • Austin, TX

Publications

Us Patents

Triblock Polypeptide-Based Nanoparticles For The Delivery Of Hydrophilic Drugs

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US Patent:
20200164082, May 28, 2020
Filed:
Sep 14, 2017
Appl. No.:
16/332865
Inventors:
- Durham NC, US
Jayanta Bhattacharyya - Durham NC, US
International Classification:
A61K 47/64
A61K 31/506
A61K 9/51
A61P 35/00
Abstract:
Described herein are compositions that may include a triblock self-assembling polypeptide and a molecule attached to the polypeptide. Also described herein are methods of making the compositions and methods of using the compositions.

Niclosamide-Conjugated Polypeptide Nanoparticles

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US Patent:
20190083638, Mar 21, 2019
Filed:
Jul 25, 2018
Appl. No.:
16/045556
Inventors:
- Durham NC, US
Jayanta Bhattacharyya - Durham NC, US
Robert A. Mook - Chapel Hill NC, US
Jiangbo Wang - Durham NC, US
Ivan Spasojevic - Durham NC, US
Richard Premont - Durham NC, US
Xinghai Li - Durham NC, US
Ashutosh Chilkoti - Durham NC, US
International Classification:
A61K 47/64
A61K 31/167
A61P 35/00
A61P 19/02
A61P 3/08
A61K 47/69
Abstract:
Disclosed herein are conjugates of a therapeutic compound and polypeptides, such as a conjugate of niclosamide and an elastin-like polypeptide. These conjugates may form nanoparticles through self-assembly, which improve the solubility, bioavailability, and pharmacokinetic profiles of the therapeutic compound. Also disclosed are methods for treating cancer, parasite infection, bacterial infection, viral infection, metabolic diseases, Type II diabetes, NASH, NAFLD, artery constriction, endometriosis, neuropathic pain, rheumatoid arthritis, sclerodermatous graft-versus-host disease, and systemic sclerosis.

Genetically Encoded Intrinsically Disordered Stealth Polymers For Delivery And Methods Of Using Same

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US Patent:
20180228908, Aug 16, 2018
Filed:
Aug 4, 2016
Appl. No.:
15/749797
Inventors:
- Durham NC, US
Samagya Banskota - Durham NC, US
Parisa Yousefpour - Durham NC, US
Jayanta Bhattacharyya - Durham NC, US
International Classification:
A61K 47/64
A61K 47/10
A61K 47/60
A61P 35/00
C12N 15/70
Abstract:
Provided herein are conjugates including a polypeptide and one or more drug molecules. The polypeptide includes one or more charged motifs, and may further include one or more uncharged motifs. The conjugates may be used to effectively deliver the drug molecule to a subject.
Jayanta P Bhattacharyya from Raleigh, NC, age ~90 Get Report