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Ivar I Giaever

from Schenectady, NY
Age ~95

Ivar Giaever Phones & Addresses

  • 2080 Van Antwerp Rd, Schenectady, NY 12309 (518) 374-9708
  • Niskayuna, NY
  • 2080 Van Antwerp Rd, Schenectady, NY 12309 (718) 320-0837

Work

Position: Retired

Education

Degree: Associate degree or higher

Resumes

Resumes

Ivar Giaever Photo 1

Chief Technology Officer

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Location:
Schenectady, NY
Industry:
Biotechnology
Work:
Applied Biophysics
Chief Technology Officer
Ivar Giaever Photo 2

Chief Technology Officer

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Location:
Schenectady, NY
Industry:
Biotechnology
Work:
Applied Biophysics, Inc.
Chief Technology Officer
Education:
Norwegian Institute of Technology 1948 - 1952
Skills:
R&D
Biomedical Engineering
Software Engineering
Design Control
Matlab
Lifesciences
Iso 13485
System Architecture
Management
Product Management
Biotechnology
Labview
Experimaental Physics
Languages:
English
German
French
Ivar Giaever Photo 3

Chief Financial Officer

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Location:
Schenectady, NY
Work:
App Lied Biophysics
Chief Financial Officer

Business Records

Name / Title
Company / Classification
Phones & Addresses
Ivar Giaever
President, Chief Technology Officer
APPLIED BIOPHYSICS, INC
Commercial Physical Research · Other Biological Prod Mfg
185 Jordan Rd, Troy, NY 12180
(518) 880-6860, (518) 880-6865, (518) 276-2165

Publications

Us Patents

Electrical Wounding Assay For Cells In Vitro

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US Patent:
7332313, Feb 19, 2008
Filed:
Jun 5, 2002
Appl. No.:
10/163322
Inventors:
Ivar Giaever - Schenectady NY, US
Charles R. Keese - Schoharie NY, US
Assignee:
Applied BioPhysics, Inc. - Troy NY
International Classification:
A46B 3/08
US Classification:
4351734, 4351735, 4351736, 204164, 204555, 20440301, 20440313
Abstract:
A method and system for electrically wounding and/or monitoring cell activity in vitro. The invention comprises methods and systems for wounding and/or monitoring cells that place a cell culture on a well that has an exposed electrode. The cell culture can then be wounded and/or monitored using the electrode.

Real-Time Impedance Assay To Follow The Invasive Activities Of Metastatic Cells In Culture

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US Patent:
7399631, Jul 15, 2008
Filed:
Sep 10, 2004
Appl. No.:
10/938086
Inventors:
Ivar Giaever - Schenectady NY, US
Charles R. Keese - Schoharie NY, US
Assignee:
Applied Biophysics, Inc. - Troy NY
International Classification:
C12N 5/00
C12N 5/02
US Classification:
435325
Abstract:
The present invention provides methods for the assessment of the metastatic potential of cells by measuring the effect of the cells on the impedance of an electrode. Accordingly, the present invention similarly provides methods for establishing indicators of metastatic potential based on a cell's effect on impedance. Such methods may be employed in vitro or in vivo. In some embodiments, the electrode is coated with endothelial or epithelial cells.

Method And Apparatus For Facilitating Evaluating Migration Of Cells In Vitro

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US Patent:
8227223, Jul 24, 2012
Filed:
Jan 27, 2009
Appl. No.:
12/360376
Inventors:
Ivar Giaever - Schenectady NY, US
Charles R. Keese - Schoharie NY, US
Assignee:
Applied Biophysics, Inc. - Troy NY
International Classification:
C12N 13/00
US Classification:
4351734, 4351735, 4351736
Abstract:
Method and apparatus for processing a cell culture are provided. The method includes establishing a cell culture within a holding device having one or more wells, each well holding a cell culture, and including a well substrate with at least one electrode in contact with the cell culture; periodically applying at least one electrical pulse to the at least one electrode to prevent cells from attaching to and achieving confluence over the at least one electrode while allowing cells to attach to and achieve confluence over other portions of the well substrate; and discontinuing the periodically applying of the at least one electrical pulse to the at least one electrode after cells have achieved confluence over the other portions of the well substrate, and thereafter, monitoring the cell culture to monitor migration of cells over the electrode(s) from the other portions of the well substrate.

Electrode Cleaning Using Electrical Pulse

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US Patent:
20070175494, Aug 2, 2007
Filed:
Feb 2, 2007
Appl. No.:
11/670464
Inventors:
Ivar Giaever - Schenectady NY, US
Charles R. Keese - Schoharie NY, US
International Classification:
B08B 3/12
US Classification:
134 1
Abstract:
Cleaning an electrode used for acquiring measurement data while the electrode is contacting a medium using a set of electrical pulses. An electrical pulse causes a voltage drop between approximately 0.01 Volts and approximately 10 Volts across the electrode. A particular voltage drop and/or other aspects of the pulse(s) can be selected based on the voltage source, electrode, medium, and/or the like. In an illustrative embodiment, the voltage drop is between approximately 1.0 and approximately 1.5 volts.

Electrical Measurement Of Cell Invasion

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US Patent:
20070182417, Aug 9, 2007
Filed:
Feb 2, 2007
Appl. No.:
11/670480
Inventors:
Ivar Giaever - Schenectady NY, US
Charles R. Keese - Schoharie NY, US
International Classification:
G01N 27/416
G01N 27/00
US Classification:
324426, 324 711
Abstract:
The electrical measurement of invasive cell movement is provided. A gel layer is added to a well including a substrate having an electrode thereon. A medium is added over the gel layer. One of the medium and the gel layer can include cells and the other of the medium and the gel layer can comprise a compound to be evaluated for its influence on cell migration. An electrical signal is applied to the electrode and a property (e.g., impedance) of the electrical signal is measured. By analyzing the property, it can be determined whether and to what extent cells are in contact with the electrode. An influence of the compound on cell migration can be correlated with the property.

Apparatus For Faciltiating Evaluating Migration Of Cells In Vitro

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US Patent:
20120288922, Nov 15, 2012
Filed:
Jul 23, 2012
Appl. No.:
13/555454
Inventors:
Ivar GIAEVER - Schenectady NY, US
Charles R. KEESE - Schoharie NY, US
Assignee:
APPLIED BIOPHYSICS, INC. - Troy NY
International Classification:
C12M 1/42
US Classification:
4352871
Abstract:
Method and apparatus for processing a cell culture are provided. The method includes establishing a cell culture within a holding device having one or more wells, each well holding a cell culture, and including a well substrate with at least one electrode in contact with the cell culture; periodically applying at least one electrical pulse to the at least one electrode to prevent cells from attaching to and achieving confluence over the at least one electrode while allowing cells to attach to and achieve confluence over other portions of the well substrate; and discontinuing the periodically applying of the at least one electrical pulse to the at least one electrode after cells have achieved confluence over the other portions of the well substrate, and thereafter, monitoring the cell culture to monitor migration of cells over the electrode(s) from the other portions of the well substrate.

Magnetic Separation Of Biological Particles

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US Patent:
39705188, Jul 20, 1976
Filed:
Jul 1, 1975
Appl. No.:
5/592195
Inventors:
Ivar Giaever - Schenectady NY
Assignee:
General Electric Company - Schenectady NY
International Classification:
G01N 2700
G01N 3316
US Classification:
195 15
Abstract:
Small magnetic particles coated with an antibody layer are used to provide large and widely-distributed surface area for sorting out and separating select viruses, bacteria and other cells from multi-cell, bacteria or virus populations.

Method For Detection Of Biological Particles

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US Patent:
40411460, Aug 9, 1977
Filed:
May 1, 1975
Appl. No.:
5/573610
Inventors:
Ivar Giaever - Schenectady NY
Assignee:
General Electric Company - Schenectady NY
International Classification:
G01N 3300
G01N 3316
A61K 4300
US Classification:
424 1
Abstract:
A monomolecular layer of first biological particles is absorbed on the surface of a non-reactive substrate. The coated substrate is exposed to a solution suspected of containing second biological particles specific to the first biological particles. Next, the coated substrate is subjected to a tagging step, following which it is exposed to a cleaving agent solution which cleaves the bond between the first and second biological particles. The used cleaving agent solution is then examined by a tag-sensing instrument following possible concentration thereof for determining whether tag-bearing second particles have been removed. The tags may, for example, be radioactive, fluorescent, etc. A supplement is described, wherein the coated substrate is studied with a tag-sensing instrument before and after exposure of the coated substrate to the cleaving agent solution to help provide said determination.

Wikipedia References

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Ivar Giaever

Ivar I Giaever from Schenectady, NY, age ~95 Get Report