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Hongmei Li Phones & Addresses

  • Stamford, CT
  • Greenwich, CT
  • Jersey City, NJ
  • Redwood City, CA
  • Mountain View, CA
  • Edison, NJ
  • Pittsburgh, PA

Professional Records

License Records

Hongmei Li

Phone:
(619) 414-4477
License #:
85462 - Active
Category:
Health Care
Issued Date:
Mar 1, 2017
Effective Date:
Mar 1, 2017
Expiration Date:
Aug 31, 2017
Type:
Massage Therapist

Medicine Doctors

Hongmei Li Photo 1

Hongmei Li

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Resumes

Resumes

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Hongmei Li

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Hongmei Li Photo 3

Hongmei Li

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Hongmei Li Photo 4

Chief Financial Officer

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Work:
Winfund Investment
Chief Financial Officer
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Hongmei Li

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Hongmei Li Photo 6

Medical Director

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Industry:
Medical Practice
Work:
Aurora Diagnostics Dermdx Ne
Medical Director
Skills:
Microsoft Office
Clinical Research
Medicine
Healthcare
Hospitals
Hongmei Li Photo 7

Hongmei Li

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Publications

Us Patents

Substituted N-Arylsulfonylheterocyclic Amines As Gamma-Secretase Inhibitors

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US Patent:
7998958, Aug 16, 2011
Filed:
Dec 8, 2009
Appl. No.:
12/633311
Inventors:
Hubert B. Josien - Jersey City NJ, US
John W. Clader - Cranford NJ, US
Thomas A. Bara - Scotch Plains NJ, US
Ruo Xu - Watchung NJ, US
Hongmei Li - Warren NJ, US
Dmitri A. Pissarnitski - Scotch Plains NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
Assignee:
Schering Corporation - Rahway NJ
International Classification:
A61K 31/535
C07D 413/14
US Classification:
5142345, 544116
Abstract:
Disclosed are novel gamma secretase inhibitors of the formula:Also disclosed are methods for inhibiting gamma secretase, for treating one or more neurodegenerative diseases, for inhibiting the deposition of beta amyloid protein, and for treating Alzheimer's disease using the compounds of formula (I).

Benzenesulfonyl-Chromane, Thiochromane, Tetrahydronaphthalene And Related Gamma Secretase Inhibitors

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US Patent:
8067621, Nov 29, 2011
Filed:
Jan 18, 2007
Appl. No.:
11/654821
Inventors:
Theodros Asberom - West Orange NJ, US
Thomas A. Bara - Linden NJ, US
Chad E. Bennett - Metuchen NJ, US
Duane A. Burnett - Bernardsville NJ, US
Mary Ann Caplen - Sayreville NJ, US
John W. Clader - Cranford NJ, US
David J. Cole - Springfield NJ, US
Martin S. Domalski - Verona NJ, US
Hubert B. Josien - Jersey City NJ, US
Chad E. Knutson - Garwood NJ, US
Hongmei Li - Warren NJ, US
Mark D. McBriar - Clinton NJ, US
Dmitri A. Pissarnitski - Scotch Plains NJ, US
Li Qiang - Edison NJ, US
Murali Rajagopalan - Edison NJ, US
Jing Su - Scotch Plains NJ, US
Haiqun Tang - Belle Mead NJ, US
Ruo Xu - Watchung NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C07D 493/00
A61K 31/35
US Classification:
549387, 514455
Abstract:
This invention discloses novel gamma secretase inhibitors of the formula:.

Benzenesulfonyl-Chromane, Thiochromane, Tetrahydronaphthalene And Related Gamma Secretase Inhibitors

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US Patent:
8569521, Oct 29, 2013
Filed:
Oct 6, 2011
Appl. No.:
13/267324
Inventors:
Theodros Asberom - West Orange NJ, US
Thomas A. Bara - Linden NJ, US
Chad E. Bennett - Metuchen NJ, US
Duane A. Burnett - Bernardsville NJ, US
Mary Anne Caplen - Sayreville NJ, US
John W. Clader - Millton VT, US
David J. Cole - Springfield NJ, US
Martin S. Domalski - Verona NJ, US
Hubert B. Josien - Jersey City NJ, US
Chad E. Knutson - Garwood NJ, US
Hongmei Li - Warren NJ, US
Mark D. McBriar - Clinton NJ, US
Dmitri A. Pissarnitski - Scotch Plains NJ, US
Li Qiang - Edison NJ, US
Murali Rajagopalan - Edison NJ, US
Jing Su - Scotch Plains NJ, US
Haiqun Tang - Belle Mead NJ, US
Ruo Xu - Watchung NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
C07D 493/00
US Classification:
549387
Abstract:
This invention discloses novel gamma secretase inhibitors of the formula:.

Substituted N-Arylsulfonylheterocyclic Amines As Gamma-Secretase Inhibitors

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US Patent:
20060040936, Feb 23, 2006
Filed:
Jun 28, 2005
Appl. No.:
11/168797
Inventors:
Hubert Josien - Jersey City NJ, US
John Clader - Cranford NJ, US
Thomas Bara - Linden NJ, US
Ruo Xu - Watchung NJ, US
Hongmei Li - Warren NJ, US
Dmitri Pissarnitski - Scotch Plains NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
International Classification:
A61K 31/5377
A61K 31/498
A61K 31/496
A61K 31/46
C07D 43/02
C07D 413/02
C07D 487/04
US Classification:
514235200, 514304000, 514249000, 514300000, 514253010, 514316000, 544124000, 544351000, 544360000, 546125000, 546187000
Abstract:
This invention discloses novel gamma secretase inhibitors of the formula: wherein:

Substituted N-Arylsulfonylheterocyclic Amines As Gamma-Secretase Inhibitors

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US Patent:
20100087425, Apr 8, 2010
Filed:
Dec 8, 2009
Appl. No.:
12/633286
Inventors:
Hubert B. Josien - Jersey City NJ, US
John W. Clader - Crawford NJ, US
Thomas A. Bara - Linden NJ, US
Ruo Xu - Watchung NJ, US
Hongmei Li - Warren NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
International Classification:
A61K 31/5377
C07D 413/14
C07D 413/12
C07D 417/12
C07D 417/14
A61K 31/541
A61P 25/00
A61P 25/28
US Classification:
5142278, 544130, 544121, 544141, 544 85, 544116, 544 582, 5142372, 5142358, 5142318, 5142332
Abstract:
This invention discloses novel gamma secretase inhibitors of the formula:One or more compounds of formula I, or formulations comprising such compounds, may be useful, e.g. in treating Alzheimer's Disease.

Gamma Secretase Modulators For The Treatment Of Alzheimer's Disease

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US Patent:
20110027264, Feb 3, 2011
Filed:
Feb 26, 2009
Appl. No.:
12/919574
Inventors:
Xianhai Huang - Warren NJ, US
Xianghai Huang - Warren NJ, US
Anandan Palani - Bridgewater NJ, US
Robert G. Aslanian - Rockaway NJ, US
Zhaoning Zhu - Plainsboro NJ, US
Dmitri A. Pissarnitski - Scotch Plains NJ, US
Hongmei Li - Warren NJ, US
William J. Greenlee - Teaneck NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
Jun Qin - Somerset NJ, US
Pawan Dhondi - Somerset NJ, US
International Classification:
A61K 39/395
C07D 401/12
C07D 221/20
A61K 38/16
A61K 31/454
A61K 31/438
A61P 25/28
US Classification:
4241301, 546210, 546 16, 514 178, 514326, 514278
Abstract:
This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula: Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's disease using the compounds of formula (I).

Tetrahydropyranochromene Gamma Secretase Inhibitors

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US Patent:
20110236400, Sep 29, 2011
Filed:
Jul 1, 2008
Appl. No.:
12/665580
Inventors:
Thomas A. Bara - Scotch Plains NJ, US
Duane A. Burnett - Bernardsville NJ, US
John W. Clader - Cranford NJ, US
Martin S. Domalski - Verona NJ, US
Yan Jin - Princeton NJ, US
Hubert B. Josien - Jersey City NJ, US
Hongmei Li - Warren NJ, US
Xian Liang - Monmouth Junction NJ, US
Dmitri A. Pissarnitski - Scotch Plains NJ, US
Jesse K. Wong - Monroe Township NJ, US
Ruo Xu - Watchung NJ, US
Zhiqiang Zhao - Scotch Plains NJ, US
Paul E. McNamara - Scotch Plains NJ, US
International Classification:
A61K 39/395
C07D 493/04
C07D 311/80
C07D 407/12
A61K 31/35
A61K 31/352
A61K 31/381
A61P 25/28
A61P 29/00
A61P 31/00
C07C 201/12
C07C 67/343
US Classification:
4241721, 549387, 549390, 549 60, 514455, 514444, 560 20, 560 81
Abstract:
Disclosed are novel gamma secretase inhibitors of the formula. Also disclosed are methods of inhibiting gamma-secretase, methods of treating neurodegenerative diseases, and methods of treating Alzheimer's Disease. Also disclosed are processes for preparing alkenes in one reaction step using a mixture of an aldehyde (or ketone) and an alkyl substituted with two electron withdrawing groups, and reacting the mixture with: (a) a sulfonyl halide (e.g., a sulfonyl chloride) and a basic tertiary amine, or, (b) a sulfonyl anhydride and a basic amine, or (c) an aryl-C(O)-halide and a basic tertiary amine, or (d) an aryl-C(O)—O—C(O)-aryl and a basic tertiary amine, or (e) an heteroaryl-C(O)-halide and a basic tertiary amine, or (f) a heteroaryl-C(O)—O—C(O)-heteroaryl and a basic tertiary amine.

Gamma Secretase Modulators

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US Patent:
20110294784, Dec 1, 2011
Filed:
Dec 18, 2009
Appl. No.:
13/140987
Inventors:
Theodros Asberom - West Orange NJ, US
Xianhai Huang - Warren NJ, US
Zhaoning Zhu - Plainsboro NJ, US
John Clader - Milton VT, US
Dmitri Pissarnitski - Scotch Plains NJ, US
Hubert Josien - Jersey City NJ, US
Hongmei Li - Warren NJ, US
International Classification:
A61K 31/553
A61P 27/00
A61P 25/28
A61P 9/10
C07D 498/04
A61P 25/00
US Classification:
51421109, 540552
Abstract:
This invention provides novel compounds that are modulators of gamma secretase. The compounds have the formula (Chemical formula should be inserted here as it appears on abstract in paper form). Also disclosed are methods of modulating gamma secretase activity and methods of treating Alzheimer's Disease using the compounds of formula (I).
Hongmei Li from Stamford, CT, age ~56 Get Report