US Patent:
20110015215, Jan 20, 2011
Inventors:
Paul Deghetto - Bound Brook NJ, US
Nagy E. Fawzy - Piscataway NJ, US
Gary Fech - Perth Amboy NJ, US
Kenneth M. Wells - Hillsborough NJ, US
Wenju Wu - Modesto CA, US
International Classification:
A61K 31/506
C07D 401/14
A61P 3/10
A61P 3/00
A61P 3/06
A61P 3/04
Abstract:
The present invention is directed to a novel crystalline forms of 4-[6-(6-methanesulfonyl-2-methyl-pyridin-3-ylamino)-5-methoxy-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester, pharmaceutical compositions containing said crystalline form and the use of said crystalline forms in the treatment of metabolic related disorders. The present invention is further directed to processes for the preparation of the crystalline forms of 4-[6-(6-methanesulfonyl-2-methyl-pyridin-3-ylamino)-5-methoxy-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid isopropyl ester.