Zhiyu Li Phones & Addresses
-
6533 Limerick Ct, Clarksville, MD 21029 (301) 318-9168
-
406 Curry Ford Ln, Gaithersburg, MD 20878 (301) 947-9552
-
Chevy Chase, MD
Public records
Vehicle Records
Zhiyu Li
View pageAddress:
406 Curry Frd Ln, Gaithersburg, MD 20878
VIN:
5FNRL38417B035603
Make:
HONDA
Model:
ODYSSEY
Year:
2007
Publications
Us Patents
Methods For Coupling Of Molecules To Metal/Metal Oxide Surfaces
View pageUS Patent:
20130034893, Feb 7, 2013
Filed:
Aug 3, 2012
Appl. No.:
13/566003
Inventors:
Zhiyu Li - Woodstock MD, US
Thomas Russell - Doylestown PA, US
Jun Gao - Jinan, CN
Thomas Russell - Doylestown PA, US
Jun Gao - Jinan, CN
International Classification:
C07K 1/107
C07K 17/02
C07K 14/00
C12N 11/14
C07K 14/765
C07K 17/02
C07K 14/00
C12N 11/14
C07K 14/765
US Classification:
435176, 530402, 530363, 530400, 5303913
Abstract:
Functionalized magnetic particles are emerging as a reliable and convenient technique in the purification of biomacromolecules (proteins and nucleic acids). We disclose a novel coupling procedure that can be used to create stable ferromagnetic nickel particles coated with Protein A for the affinity purification of antibody. The protein purification procedure is gentle, scalable, automatable, efficient and economical. By modifying the functional groups of amino acids in the protein coating, nickel particles can be used not only for affinity purification but for other sample preparation and chromatographic applications as well including nucleic acid isolations. The method can be easily modified for small and medium scale antibody purification in lab and pre-clinical research.