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Yuan Hai Xu

from San Francisco, CA
Age ~75

Yuan Xu Phones & Addresses

  • 614 Pine St, San Francisco, CA 94108 (415) 391-3936 (415) 986-1791
  • Thousand Oaks, CA

Professional Records

Lawyers & Attorneys

Yuan Xu Photo 1

Yuan Xu - Lawyer

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ISLN:
1000600556
Admitted:
2007

Business Records

Name / Title
Company / Classification
Phones & Addresses
Yuan Xu
Streamsaga, LLC
Nonclassifiable Establishments
206 Ironwood Rd, Alameda, CA 94502

Publications

Us Patents

Reverse-Phase Hplc Assay For Plasminogen Activators

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US Patent:
6593097, Jul 15, 2003
Filed:
Nov 1, 2000
Appl. No.:
09/703695
Inventors:
Yuan Xu - Redwood City CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
G01N 33573
US Classification:
435 74
Abstract:
A process is described for monitoring the effectiveness of a purification process in removing plasminogen activator (PA) endogenous to Chinese hamster ovary (CHO) cells from a sample containing human tPA or variants thereof. This process comprises incubating the sample with a protease capable of specifically cleaving the Arg âIle bond of human wild-type tPA and then with denaturing/reducing agents in respective amounts effective to reduce the disulfide bonds of human wild-type tPA; subjecting the sample to a reversed-phase high-performance liquid chromatography step, and analyzing the elution profile from the chromatography step for the amount of PA endogenous to the CHO cells present therein.

Reverse-Phase Hplc Assay For Plasminogen Activators

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US Patent:
6828118, Dec 7, 2004
Filed:
May 21, 2003
Appl. No.:
10/443701
Inventors:
Yuan Xu - Redwood City CA
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C12Q 137
US Classification:
435 23
Abstract:
A process is described for monitoring the effectiveness of a purification process in removing plasminogen activator (PA) endogenous to Chinese hamster ovary (CHO) cells from a sample containing human tPA or variants thereof. This process comprises incubating the sample with a protease capable of specifically cleaving the Arg -Ile bond of human wild-type tPA and then with denaturing/reducing agents in respective amounts effective to reduce the disulfide bonds of human wild-type tPA; subjecting the sample to a reversed-phase high-performance liquid chromatography step, and analyzing the elution profile from the chromatography step for the amount of PA endogenous to the CHO cells present therein.

Azaindazole Compounds And Methods Of Use

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US Patent:
7524845, Apr 28, 2009
Filed:
Jun 22, 2006
Appl. No.:
11/474132
Inventors:
Penglie Zhang - Foster City CA, US
Andrew M. K. Pennell - San Francisco CA, US
John J. Kim Wright - Redwood City CA, US
Wei Chen - Fremont CA, US
Manmohan R. Leleti - Sunnyvale CA, US
Yandong Li - San Jose CA, US
Lianfa Li - Palo Alto CA, US
Yuan Xu - Fremont CA, US
Assignee:
ChemoCentryx, Inc. - Mountain View CA
International Classification:
A61K 31/5377
A61K 31/496
C07D 471/04
C07D 487/04
US Classification:
5142358, 51425304, 514248, 514249, 5142621, 544121, 544362, 544236, 544262, 544350
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

Azaindazole Compounds And Methods Of Use

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US Patent:
7777035, Aug 17, 2010
Filed:
May 22, 2007
Appl. No.:
11/752201
Inventors:
Penglie Zhang - Foster City CA, US
Andrew M. K. Pennell - San Francisco CA, US
John J. Kim Wright - Redwood City CA, US
Wei Chen - Fremont CA, US
Manmohan R. Leleti - Sunnyvale CA, US
Yandong Li - San Jose CA, US
Lianfa Li - Palo Alto CA, US
Yuan Xu - Fremont CA, US
Mark M. Gleason - Redwood City CA, US
Yibin Zeng - San Mateo CA, US
Kevin Lloyd Greenman - Burlingame CA, US
Assignee:
Chemocentryx, Inc. - Mountain View CA
International Classification:
C07D 471/04
US Classification:
544362, 544236, 544262, 544350, 514249, 5142621, 514284, 51425304
Abstract:
Methods are provided for the synthesis of 1-[4-(substituted phenyl)-piperazin-1-yl ] -2- [3-(1H-imidazol-2-yl)-pyrazolo [3,4-b]pyridin-1-yl]-ethanone compounds via construction of the imidazole portion onto the corresponding aldehyde or nitrile compounds.

Azaindazole Compounds And Methods Of Use

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US Patent:
8383630, Feb 26, 2013
Filed:
Jul 1, 2010
Appl. No.:
12/829312
Inventors:
Penglie Zhang - Foster City CA, US
Andrew M. K. Pennell - San Francisco CA, US
John J. Kim Wright - Redwood City CA, US
Wei Chen - Fremont CA, US
Manmohan R. Leleti - Sunnyvale CA, US
Yandong Li - San Jose CA, US
Lianfa Li - Palo Alto CA, US
Yuan Xu - Fremont CA, US
Assignee:
Chemocentryx, Inc. - Mountain View CA
International Classification:
A61K 31/437
A61P 19/02
US Classification:
51425304, 544362
Abstract:
Provided are methods for the treatment of rheumatoid arthritis using compounds of formula Ia and Ib:.

Dimensionally Stable Silicone Hydrogel Contact Lenses

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US Patent:
8445614, May 21, 2013
Filed:
Feb 24, 2012
Appl. No.:
13/404034
Inventors:
Charles A. Francis - Union City CA, US
Ying Zheng - Pleasonton CA, US
Yuan Xu - Fremont CA, US
Li Yao - San Ramon CA, US
Arthur Back - Danville CA, US
Ye Hong - Pleasanton CA, US
Charlie Chen - San Ramon CA, US
Assignee:
CooperVision International Holding Company, LP - St. Michael
International Classification:
C08F 230/08
C08F 290/06
G02B 1/04
US Classification:
526279, 523106, 523107
Abstract:
Dimensionally stable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1):.

Ambruticin Vs Compounds

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US Patent:
20070015823, Jan 18, 2007
Filed:
Dec 16, 2005
Appl. No.:
11/305802
Inventors:
David Myles - Kensington CA, US
Zhan Wang - El Dorado Hills CA, US
Yuan Xu - Fremont CA, US
Bryan Julien - Oakland CA, US
Eduardo Rodriguez - Rosario, AR
Mark Shimazu - Hayward CA, US
Greg Buchanan - Hayward CA, US
Leonard Katz - Oakland CA, US
International Classification:
A61K 31/35
C07D 405/14
C07D 405/02
US Classification:
514460000, 549415000
Abstract:
Antifungal compounds represented by formula I where R, R, Rand Rare as defined herein. Isolated or purified naturally occurring 20,21-dihydro ambruticin compounds. The invention also provides ambM, ambO, ambP, and ambS mutant strains; a recombinant strain that produces 24-norambruticin compounds; and a method for treating a fungal infection using a compound of this invention.

Azaindazole Compounds And Methods Of Use

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US Patent:
20090252779, Oct 8, 2009
Filed:
Apr 3, 2009
Appl. No.:
12/418516
Inventors:
Penglie Zhang - Foster City CA, US
Andrew M.K. Pennell - San Francisco CA, US
John J. Kim Wright - Redwood City CA, US
Wei Chen - Fremont CA, US
Manmohan R. Leleti - Sunnyvale CA, US
Yandong Li - San Jose CA, US
Lianfa Li - Palo Alto CA, US
Yuan Xu - Fremont CA, US
Assignee:
ChemoCentryx, Inc. - Mountain View CA
International Classification:
A61F 2/04
C07D 471/04
A61K 31/497
A61K 31/5377
US Classification:
424423, 544362, 51425304, 5142345, 544127
Abstract:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

Isbn (Books And Publications)

Orthogonal Polynomials of Several Variables

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Author

Yuan Xu

ISBN #

0521800439

Yuan Hai Xu from San Francisco, CA, age ~75 Get Report