Wei Guo Li

7420001, Sep 2, 2008

Dec 1, 2004

11/001589

Jeremy Ian Levin - New City NY, US
Frank Lovering - Acton MA, US
Yonghan Hu - Burlington MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Jun Jun Wu - Arlington MA, US
Rajeev Hotchandani - Somerville MA, US
Jason Shaoyun Xiang - Winchester MA, US
Xuemei Du - Valley Cottage NY, US
Derek Cecil Cole - New City NY, US
Steve Yikkai Tam - Wellesley MA, US

Wyeth - Madison NJ

A61K 31/343
C07D 307/81

514469, 514470, 549466, 549467

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.

7460119, Dec 2, 2008

Sep 26, 2005

11/235408

Wei Li - East Brunswick NJ, US

Siemens Medical Solutions USA, Inc. - Malvern PA

G06T 15/40

345421

A method of accelerating texture-based volume rendering is provided. The method includes the following steps. A plurality of levels of granularity comprising a plurality of sub-volumes organized in a hierarchical structure are built. The hierarchical structure is ordered top-down from a coarsest level of granularity to a finest level of a granularity. A visibility factor is determined for each of the plurality of sub-volumes. The visibility factor represents a ratio of visible voxels in the corresponding sub-volume. The plurality of sub-volumes are traversed top-down from the coarsest level of granularity to the finest level of granularity. While traversing each of the plurality of sub-volumes, the corresponding sub-volume is rendered and all children of the rendered sub-volume are skipped, if the visibility factor is greater than given threshold.

7711162, May 4, 2010

Sep 26, 2005

11/235410

Wei Li - East Brunswick NJ, US

Siemens Medical Solutions USA, Inc. - Malvern PA

G06K 9/00
G06K 9/32
G06T 15/40

382128, 382294, 345421

An exemplary method of combining two images to form a fused image is provided. A hierarchical structure for each of a plurality of volumes is built. All blocks in each of the hierarchical structures that intersect a slicing plane are found. Each of the plurality of volumes is divided into stacks of parallel slices, and the parallel slices are sorted by visibility order. A next slice in the sorted parallel slices is chosen. The next slice belongs to a current volume. Rendering parameters are changed if the current volume is different from a previous volume associated with the chosen slice in a previous iteration of the step of choosing the slice. Based on the rendering parameters, the next slice is rendered by intersecting the slicing plane with the blocks corresponding to the current volume. The steps of choosing the slice, changing the rendering parameters, and rendering the slice are repeated until all of the sorted parallel slices are rendered.

8184120, May 22, 2012

Feb 17, 2009

12/371959

Wei Hong - Edison NJ, US
Wei Li - Princeton NJ, US

Siemens Aktiengesellschaft - München

G06T 17/00
G06T 15/00
G06T 15/04

345424, 345582

Described herein is a system and method for facilitating large volume data processing and rendering. An exemplary system includes at least one processor coupled to a first memory, wherein the processor is configured to organize the large volume data in the first memory into one or more bricks. In addition, at least one graphics processing unit (GPU) is coupled to the processor and a second memory. The GPU is configured to process at least one or more bricks transferred from the first memory to the second memory to produce intermediate processing results, and to further render the intermediate processing results.

8563543, Oct 22, 2013

Oct 6, 2010

13/392955

Jack D. Scott - Scotch Plains NJ, US
Andrew W. Stamford - Chatham NJ, US
Eric J. Gilbert - Scotch Plains NJ, US
Jared N. Cumming - Garwood NJ, US
Ulrich Iserloh - Hoboken NJ, US
Lingyan Wang - East Brunswick NJ, US
Wei Li - Belle Mead NJ, US

Merck Sharp & Dohme Corp. - Rahway NJ

A61K 31/54

5142225, 544 8

In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (a) and include tautomers, solvates, prodrugs, esters, and deuterates thereof, and pharmaceutically acceptable salts of said compounds, tautomers, solvates, prodrugs, esters, and deuterates, wherein each of R, R, R, R, R, R, ring A, ring B, ring C, m, n, p, q, -L-, -L-, L-, and L- is selected independently and as defined herein. The compounds of the invention have, surprisingly and advantageously, improved solution stability. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use in treating pathologies associated with amyloid beta (Aβ) protein, including Alzheimers Disease, are also disclosed.

20030151604, Aug 14, 2003

Nov 21, 2002

10/301399

Arie Kaufman - Plainview NY, US
Wei Li - Stony Brook NY, US

RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

G06T015/00

345/419000

A system and method for texture-based volume rendering accelerated by contouring texture hulls is provided. Bounding geometries, such as rectangles, cuboids, or the like surrounding the non-empty regions as well as the contouring borders of the non-empty regions are found. The bounding shapes are treated as the hulls of the non-empty sub-textures. The nonempty sub-textures are stored and rendered. Texels outside the hulls are skipped.

20090029906, Jan 29, 2009

May 1, 2006

11/913038

Rui Rong Yuan - Fort Lee NJ, US
Wei Ping Li - Kearny NJ, US
Joseph Menonna - Dumont NJ, US
Yasuhiro Maeda - Belle Mead NJ, US
Peter Dowling - Fort Lee NJ, US

UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY - Newark NJ

C07K 14/575
C07K 9/00
A61K 38/22
A61K 38/14
A61P 29/00
A61P 37/00

514 8, 530397, 530322

The present invention provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.

20100137298, Jun 3, 2010

Jun 13, 2008

12/138752

Jeremy Ian Levin - New City NY, US
Frank Lovering - Acton MA, US
Yonghan Hu - Burlington MA, US
Jianchang Li - Carlisle MA, US
Wei Li - Acton MA, US
Jun Jun Wu - Arlington MA, US
Rajeev Hotchandani - Somerville MA, US
Jason Shaoyun Xiang - Winchester MA, US
Xuemei Du - Valley Cottage NY, US
Derek Cecil Cole - New City NY, US
Steve Yikkai Tam - Wellesley MA, US

Wyeth - Madison NJ

A61K 31/5377
G01N 33/573
C12N 9/99
A61K 31/4439
A61K 31/425
A61K 31/428
A61K 31/381
A61K 31/343
C07D 413/12
C07D 405/10
C07D 277/02
C07D 275/02
C07D 209/42
C07D 333/52
C07D 307/78
A61P 35/00

5142315, 435 74, 435184, 514339, 514367, 514373, 514443, 514469, 544153, 5462841, 548200, 548214, 548492, 549 57, 549468

The present invention relates to biaryl sulfonamides and their use as, for example, metalloproteinase inhibitors.