Wei Li

7629797, Dec 8, 2009

Apr 5, 2007

11/697060

Yu-Chong Tai - Pasadena CA, US
Chi-yuan Shih - Pasadena CA, US
Wei Li - Monterey Park CA, US
Siyang Zheng - Pasadena CA, US

California Institute of Technology - Pasadena CA

G01R 27/26

324684, 324686, 324663, 324664

Methods and systems for improving the sensitivity of a variety of conductivity sensing devices, in particular capacitively-coupled contactless conductivity detectors. A parallel inductor is added to the conductivity sensor. The sensor with the parallel inductor is operated at a resonant frequency of the equivalent circuit model. At the resonant frequency, parasitic capacitances that are either in series or in parallel with the conductance (and possibly a series resistance) is substantially removed from the equivalent circuit, leaving a purely resistive impedance. An appreciably higher sensor sensitivity results. Experimental verification shows that sensitivity improvements of the order of 10,000-fold are possible. Examples of detecting particulates with high precision by application of the apparatus and methods of operation are described.

8022037, Sep 20, 2011

Jan 8, 2008

12/522446

Wei Li - Altadena CA, US
Mei Chen - Altadena CA, US
David T. Woodley - Altadena CA, US

University of Southern California - Los Angeles CA

A61K 38/00
A61K 45/00

514 165, 424 852

A wound healing composition comprising an amount of heat shock protein effective to promote wound healing and a method thereof to apply the composition. A preferred heat shock protein is either full-length hsp90α or the middle domain plus the charged sequence of hsp90α. The composition is topically applied to skin wounds, covering the outer surface of the wound. The heat shock protein acts by promoting migration of both human epidermal keratinocyte and dermal fibroblasts to the wound in order to close, heal, and remodel the wound.

8410055, Apr 2, 2013

Aug 15, 2011

13/210200

Wei Li - Altadena CA, US
Mei Chen - Altadena CA, US
David T. Woodley - Altadena CA, US

University of Southern California - Los Angeles CA

A61K 38/00
A61K 45/00
A61P 43/00

514 186, 514 165, 424 852

A wound healing composition comprising an amount of heat shock protein effective to promote wound healing and a method thereof to apply the composition. A preferred heat shock protein is either full-length hsp90α or the middle domain plus the charged sequence of hsp90α. The composition is topically applied to skin wounds, covering the outer surface of the wound. The heat shock protein acts by promoting migration of both human epidermal keratinocyte and dermal fibroblasts to the wound in order to close, heal, and remodel the wound.

8455443, Jun 4, 2013

May 30, 2012

13/484162

Wei Li - Altadena CA, US
Mei Chen - Altadena CA, US
David T. Woodley - Altadena CA, US
Chieh-Fang Cheng - Alhambra CA, US

University of Southern California - Los Angeles CA

A61K 38/00
A61K 45/00

514 165, 424 852

A wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain. The composition includes a pharmaceutical medium to carry the polypeptide compound, such as an aqueous solution, suspension, dispersion, salve, ointment, gel, cream, lotion, spray or paste. Additionally, a method of applying a wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain in a concentration of from about 1 μg/ml to about 100 μg/ml for a time sufficient to heal the wound is disclosed.

8207118, Jun 26, 2012

Jul 17, 2009

12/505361

Wei Li - Altadena CA, US
Mei Chen - Altadena CA, US
David T. Woodley - Altadena CA, US
Chieh-Fang Cheng - Alhambra CA, US

University of Southern California - Los Angeles CA

A61K 38/00
A61K 45/00

514 165, 424 852

A wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain. The composition includes a pharmaceutical medium to carry the polypeptide compound, such as an aqueous solution, suspension, dispersion, salve, ointment, gel, cream, lotion, spray or paste. Additionally, a method of applying a wound healing composition comprising a class of polypeptide compounds having a polypeptide chain with 5 to 120 amino acid units per chain in a concentration of from about 1 μg/ml to about 100 μg/ml for a time sufficient to heal the wound is disclosed.

20120121595, May 17, 2012

Oct 11, 2011

13/271076

Wei Li - Altadena CA, US
David T. Woodley - Altadena CA, US
Mei Chen - Altadena CA, US

UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA

A61K 39/395
C12N 15/12
C07K 16/18
A61K 39/00
A61K 31/7105
C12Q 1/68
A61P 35/00
A61P 35/04
C12N 15/63
C12N 1/21
C12N 5/10
G01N 33/566
C07K 7/08
A61K 31/713

4241351, 530326, 536 235, 5303891, 5303881, 5303873, 53038815, 4241391, 4241331, 4241851, 514 44 R, 514 44 A, 4353201, 43525233, 435366, 435 723, 435 613

The invention provides methods for treating HIF-1α-overexpressing human tumors, inhibiting HIF-1α-overexpressing tumor invasion and preventing tumor metastasis, and/or promoting tumor prophylaxis, using various types of inhibitors against the Hsp90α from the tumors.

20230074583, Mar 9, 2023

Nov 7, 2022

17/982217

- Wilmington DE, US
John Donald Summers - Hapel Hill NC, US
Nora Sabina Radu - Landenburg PA, US
Chai Kit Ngai - Chadds ford PA, US
Wayne Atkinson - New Castle, DE
Wei Li - Middletown DE, US
Jonathan Timothy Maeyer - Haddonfield NJ, US

C08G 73/10
C08J 5/18
G02B 1/04
G02F 1/1333

Disclosed is a polyimide film that exhibits: an in-plane coefficient of thermal expansion (CTE) that is less than 75 ppm/ C. between 50 C. and 250 C.; a glass transition temperature (T) that is greater than 250 C. for the polyimide film cured at 260 C. in air; a 1% TGA weight loss temperature that is greater than 450 C.; a tensile modulus that is between 1.5 GPa and 5.0 GPa; an elongation to break that is greater than 20%; an optical retardation at 550 nm that is less than 100 nm for a 10-μm film; a birefringence at 633 nm that is less than 0.002; a haze that is less than 1.0%; a b* that is less than 3; a yellowness index that is less than 5; and an average transmittance between 380 nm and 780 nm that is greater than 88%.

20170152296, Jun 1, 2017

Nov 30, 2016

15/365908

Wei Li - Los Angeles CA, US

C07K 14/47
A61K 45/06
A61K 9/00
A61K 38/17
A61K 38/18

Recombinant polypeptides and compositions as described herein and are useful in methods to promote epidermal tissue regeneration and/or to promote wound healing in a variety of tissues subject in need thereof. The method comprises administering to a tissue or wound in need thereof an effective amount of a recombinant polypeptide operatively linked to a carrier protein or a composition containing the recombinant polypeptide linked to a carrier protein.