Wei Xin Li

8184120, May 22, 2012

Feb 17, 2009

12/371959

Wei Hong - Edison NJ, US
Wei Li - Princeton NJ, US

Siemens Aktiengesellschaft - München

G06T 17/00
G06T 15/00
G06T 15/04

345424, 345582

Described herein is a system and method for facilitating large volume data processing and rendering. An exemplary system includes at least one processor coupled to a first memory, wherein the processor is configured to organize the large volume data in the first memory into one or more bricks. In addition, at least one graphics processing unit (GPU) is coupled to the processor and a second memory. The GPU is configured to process at least one or more bricks transferred from the first memory to the second memory to produce intermediate processing results, and to further render the intermediate processing results.

8563543, Oct 22, 2013

Oct 6, 2010

13/392955

Jack D. Scott - Scotch Plains NJ, US
Andrew W. Stamford - Chatham NJ, US
Eric J. Gilbert - Scotch Plains NJ, US
Jared N. Cumming - Garwood NJ, US
Ulrich Iserloh - Hoboken NJ, US
Lingyan Wang - East Brunswick NJ, US
Wei Li - Belle Mead NJ, US

Merck Sharp & Dohme Corp. - Rahway NJ

A61K 31/54

5142225, 544 8

In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (a) and include tautomers, solvates, prodrugs, esters, and deuterates thereof, and pharmaceutically acceptable salts of said compounds, tautomers, solvates, prodrugs, esters, and deuterates, wherein each of R, R, R, R, R, R, ring A, ring B, ring C, m, n, p, q, -L-, -L-, L-, and L- is selected independently and as defined herein. The compounds of the invention have, surprisingly and advantageously, improved solution stability. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use in treating pathologies associated with amyloid beta (Aβ) protein, including Alzheimers Disease, are also disclosed.

20030151604, Aug 14, 2003

Nov 21, 2002

10/301399

Arie Kaufman - Plainview NY, US
Wei Li - Stony Brook NY, US

RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

G06T015/00

345/419000

A system and method for texture-based volume rendering accelerated by contouring texture hulls is provided. Bounding geometries, such as rectangles, cuboids, or the like surrounding the non-empty regions as well as the contouring borders of the non-empty regions are found. The bounding shapes are treated as the hulls of the non-empty sub-textures. The nonempty sub-textures are stored and rendered. Texels outside the hulls are skipped.

20070010008, Jan 11, 2007

Jun 28, 2006

11/476376

Scheffer Tseng - Pinecrest FL, US
Hua He - Miami FL, US
Wei Li - Miami FL, US

C12N 5/06
C12N 5/08

435325000, 435366000

An ex vivo method of expanding animal cells whose differentiation state is controllable by modulating TGF-β signaling includes the steps of: (a) providing an animal subject having cells with a first phenotype; (b) isolating the cells from the animal subject; (c) placing the cells in an ex vivo culture system including a culture vessel having at least one surface and a medium in contact with the at least one surface, the medium being essentially free of intact amniotic membrane and feeder cells; and (d) culturing the cells in the medium under conditions which downregulate TGF-β signaling in the cells and allow the cells to proliferate while maintaining the first phenotype.

20090029906, Jan 29, 2009

May 1, 2006

11/913038

Rui Rong Yuan - Fort Lee NJ, US
Wei Ping Li - Kearny NJ, US
Joseph Menonna - Dumont NJ, US
Yasuhiro Maeda - Belle Mead NJ, US
Peter Dowling - Fort Lee NJ, US

UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY - Newark NJ

C07K 14/575
C07K 9/00
A61K 38/22
A61K 38/14
A61P 29/00
A61P 37/00

514 8, 530397, 530322

The present invention provides isolated stabilized EPO-derived peptides and their mimics that protect against tissue damage in subjects having diverse forms of neural and non-neural organ system injury, pharmaceutical compositions containing the isolated stabilized EPO-derived peptides, methods for treating symptoms of a disease, disorder or condition having an inflammatory or an autoimmune component in a subject in need thereof, and methods for downregulating immune mediator activity in a subject in need thereof.

20110207628, Aug 25, 2011

Jun 9, 2009

13/062860

Wei Li - Miami Beach FL, US
Xiaoyu Jiang - Miami FL, US
Nora Blanca Caberoy - Miami FL, US

UNIVERSITY OF MIAMI - Miami FL

C40B 30/04
C40B 40/08
C12Q 1/68
C12N 15/63

506 9, 506 17, 435 612, 4353201

A dual display phage system for the identification of protein interaction networks and therapeutic targets.

20120093761, Apr 19, 2012

Apr 1, 2010

13/262285

Pirouz M. Daftarian - Miami FL, US
Paolo Serafini - Miami Shores FL, US
Vance Paul Lemmon - Miami FL, US
Angel Kaifer - Coral Gables FL, US
Victor L. Perez - Pinecrest FL, US
Wei Li - Miami FL, US
Bonnie Beth Blomberg - Coral Gables FL, US

UNIVERSITY OF MIAMI - Miami FL

A61K 31/785
A61P 35/00
C12N 15/09
A61P 37/04
C08G 69/48
C12N 5/07

424 7817, 525 541, 435375, 435440

Nanoparticle-based vaccines, compositions, kits and methods are used for the effective delivery of one or more antigens in vivo for vaccination and antibody (e.g., monoclonal antibody) production, and for the effective delivery of peptides, proteins, siRNA, RNA or DNA to PAPCs or MHC class II positive cells (e.g. tumor cells). Antigens may be, for example, DNA that results in expression of the gene of interest and induction of a robust and specific immune response to the expressed protein in a subject (e.g., mammal). Antigens may also be immunogenic peptides or polypeptides that are processed and presented. In one embodiment, a nanoparticle -based method to deliver antigens in vivo as described herein includes injection of a vaccine composed of a DNA encoding at least one antigen, or at least one antigenic peptide or polypeptide conjugated to a charged dendrimer (e.g., PADRE-derivatized dendrimer) that is also conjugated to a T helper epitope (e.g., PADRE). Negatively-charged plasmids bind naturally to a positively-charged PADRE-dendrimer, while peptide or polypeptide antigens can be chemically linked to the PADRE-dendrimer if they are not negatively-charged. Alternatively, negatively-charged dendrimers may be used. The compositions, kits, vaccines and methods described herein have both prophylactic and treatment applications, i.e., can be used as a prophylactic to prevent onset of a disease or condition in a subject, as well as to treat a subject having a disease or condition. A vaccine as described herein can be used to mount an immune response against any infectious pathogen or cancer.

20220310072, Sep 29, 2022

Jun 3, 2020

17/616129

- Mountain View CA, US
Ruoming Pang - New York NY, US
David Rybach - Mountain View CA, US
Yanzhang He - Palo Alto CA, US
Rohit Prabhavalkar - Mountain View CA, US
Wei Li - Fremont CA, US
Mirkó Visontai - Mountain View CA, US
Qiao Liang - Redwood City CA, US
Trevor Strohman - Sunnyvale CA, US
Yonghui Wu - Fremont CA, US
Ian C. McGraw - Menlo Park CA, US
Chung-Cheng Chiu - Sunnyvale CA, US

G10L 15/16
G10L 15/32
G10L 15/05

Two-pass automatic speech recognition (ASR) models can be used to perform streaming on-device ASR to generate a text representation of an utterance captured in audio data. Various implementations include a first-pass portion of the ASR model used to generate streaming candidate recognition(s) of an utterance captured in audio data. For example, the first-pass portion can include a recurrent neural network transformer (RNN-T) decoder. Various implementations include a second-pass portion of the ASR model used to revise the streaming candidate recognition(s) of the utterance and generate a text representation of the utterance. For example, the second-pass portion can include a listen attend spell (LAS) decoder. Various implementations include a shared encoder shared between the RNN-T decoder and the LAS decoder.