Lin Lin Li

6720346, Apr 13, 2004

Jul 5, 2002

10/190219

Shao Song Chu - Carlsbad CA
Larry Andrew Alegria - San Diego CA
Ted Michael Bleckman - La Jolla CA
Wesley Kwan Mung Chong - Encinitas CA
Rohit K. Duvadie - San Diego CA
Lin Li - San Diego CA
Siegfried Heinz Reich - Solana Beach CA
Michael B. Wallace - San Diego CA
Yi Yang - San Diego CA

Agouron Pharmaceuticals, Inc. - San Diego CA

A61K 31425

514370, 548191, 548194

Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutically acceptable salts of said metabolites are described. These agents modulate and/or inhibit the cell proliferation and activity of protein kinases and are useful as pharmaceuticals for treating malignancies and other disorders.

20110255586, Oct 20, 2011

Apr 7, 2011

13/081962

Lin Lin Li - Morganville NJ, US
Amitkumar Mahadevan - Edison NJ, US

Ikanos Communications, Inc. - Fremont CA

H04L 27/01

375231, 375230

Various systems and methods are described for performing fractionally spaced time domain equalization (TEQ). One embodiment is a method implemented in a communication system for training a fractionally spaced time domain equalizer (TEQ). The method comprises performing an initialization phase, averaging a received signal in the system to reduce effects of noise in a channel, determining a channel estimate, and aligning an ideal reference signal with the received signal. The method further comprises updating a target response filter according to a non-integer multiple of a base sampling rate, determining an adaptation error based on useful information both inside and outside a Nyquist band of the TEQ, and updating the TEQ according to the adaptation error.

20220280568, Sep 8, 2022

Aug 13, 2020

17/632869

- Duarte CA, US
Maciej KUJAWSKI - Duarte CA, US
Lin LI - Duarte CA, US
Paul J. YAZAKI - Duarte CA, US

A61K 35/17
C07K 16/28
C07K 16/30
A61K 47/68
A61K 51/10

Provided herein, inter alia, are methods of using bispecific antibody compounds which may bind immune cells and are, inter alia, useful for treating cancers. Anti-tumor antigen antibodies are connected to anti-immune antibodies through their hinge regions using, for example, click chemistry to form dual-specific, bivalent BiTES with high in vivo tumor targeting ability and tumor cytotoxicity.

20230001027, Jan 5, 2023

Sep 30, 2020

17/764708

- Duarte CA, US
Michael R. Weist - Santa Ana CA, US
Bradley J. Ahrens - San Diego CA, US
Lin Li - Monrovia CA, US
Weidong Hu - Diamond Bar CA, US

A61K 51/04

Provided herein, inter alia, are methods and compositions for detection of vascular calcification.

20210330804, Oct 28, 2021

Feb 24, 2021

17/184237

- Duarte CA, US
Hua YU - Glendora CA, US
Piotr Marek SWIDERSKI - San Dimas CA, US
John Ernest SHIVELY - Arcadia CA, US
Lin LI - Monrovia CA, US

A61K 47/68
C07K 16/08
C07K 16/18
C07K 16/40
A61K 47/54
A61K 39/44

Provided herein are cell penetrating conjugates. The conjugates include a non-cell penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone, wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular delivery of the non-cell penetrating protein. Also provided are compositions and kits comprising the cojugates.

20200197867, Jun 25, 2020

Apr 23, 2018

16/607015

- Newark NJ, US
- Minnetonka MN, US
Lin Li - Kearny NJ, US
Thomas J. McEvoy - Tofte MN, US

B01D 61/36
B01D 63/04
C02F 1/44

Exemplary embodiments in desalination by direct contact membrane distillation present a cylindrical cross-flow module containing high-flux composite hydrophobic hollow fiber membranes. The present embodiments are directed to a model that has been developed to describe the observed water production rates of such devices in multiple brine feed introduction configurations. The model describes the observed water vapor production rates for different feed brine temperatures at various feed brine flow rates. The model flux predictions have been explored over a range of hollow fiber lengths to compare the present results with those obtained earlier from rectangular modules which had significantly shorter hollow fibers.

20180236234, Aug 23, 2018

Jan 21, 2015

15/537411

- Staefa, CH
Jian Xie - Valencia CA, US
Lin Li - Valencia CA, US

A61N 1/36
A61N 1/375
A61N 1/05

A cochlear implant including a cochlear lead, an antenna, a processor case, and a printed circuit board assembly located within the processor case. The processor case may include a base with a bottom wall and first and second side walls that together define a one-piece, unitary structure, a first end wall, attached to the bottom wall and to the first and second side walls, including a first plurality of feedthrough pins, a second end wall, attached to the bottom wall and to the first and second side walls, including a second plurality of feedthrough pins, and a cover attached to the first and second side walls and to the first and second end walls.

20160317671, Nov 3, 2016

Feb 29, 2016

15/056777

- Duarte CA, US
Hua Yu - Glendora CA, US
Piotr Marek Swiderski - San Dimas CA, US
John Ernest Shively - Arcadia CA, US
Lin Li - Monrovia CA, US

A61K 47/48
C07K 16/08
C07K 16/40
A61K 39/44
C07K 16/18

Provided herein are cell penetrating conjugates. The conjugates include a non-cell penetrating protein attached to a phosphorothioate nucleic acid or phosphorothioate polymer backbone, wherein the phosphorothioate nucleic acid or phosphorothioate polymer backbone enhances intracellular delivery of the non-cell penetrating protein. Also provided are compositions and kits comprising the cojugates.