Inventors:
Peilin Chen - Cupertino CA, US
Peter Su - Mercer Island WA, US
Hao Yu - Pacheco CA, US
Lawrence J. Blecka - Walnut Creek CA, US
Patrick F. Coleman - Edmonds WA, US
Assignee:
Bio-Rad Laboratories, Inc. - Hercules CA
International Classification:
A61K 39/245
C07K 14/035
G01N 33/543
G01N 33/546
G01N 33/53
C12Q 1/70
US Classification:
435 5, 530324, 435 71, 436518, 436533
Abstract:
The present invention relates to peptides that are derived from HSV-2 glycoprotein G2 and represent HSV-2 type-specific epitopes. The present invention also provides for compositions comprising these peptides for type-specific serological diagnosis of HSV-2 infection. Methods of using these peptides for type-specific detection of HSV-2 antibodies and differentiation of HSV-2 viral infection from HSV-1 and other herpes family viral infections are further provided.