US Patent:
20080176927, Jul 24, 2008
Inventors:
Suketu Sanghvi - Kendall Park NJ, US
Mark Roach - Benicia CA, US
Joseph F. Zhou - Denville NJ, US
Eric Michael Mittleberg - Wayne NJ, US
Ping He - Miramar FL, US
Assignee:
Optimer Pharmaceuticals, Inc. - San Diego CA
International Classification:
A61K 31/335
A61P 35/00
A61P 31/12
A61P 31/00
A61P 31/04
Abstract:
The present invention is related to pharmaceutical compositions of one or more tiacumicins that exhibit improved stability, and methods of treatment using such formulations. The formulations contain one or more tiacumicins, such as difimicin, and one or more antioxidants, such as butylated hydroxytoluene, and, optionally, one or more pharmaceutically acceptable excipients.