US Patent:
20140255486, Sep 11, 2014
Inventors:
- Sodertalje, SE
Bing V. LI - Germantown MD, US
Assignee:
AstraZeneca AB - Sodertalje
International Classification:
A61K 9/28
A61K 31/403
Abstract:
A coated tablet formulation is provided which includes a medicament such as the DPP4-inhibitor, saxaglipitinor its HCl salt,which is subject to intra-molecular cyclization, which formulation includes a tablet core containing one or more fillers, and other conventional excipients, which tablet core includes a coating thereon which may include two or more layers, at least one layer of which is an inner seal coat layer which is formed of one or more coating polymers, a second layer of which is formed of medicament which is the DPP4-inhibitor and one or more coating polymers, and an optional, but preferable third outer protective layer which is formed of one or more coating polymers. A method for forming the coated tablet is also provided.
