US Patent:
20130331328, Dec 12, 2013
Inventors:
Stephen W. Byers - Takoma Park MD, US
Sivanesan Dakshanamurthy - Herndon VA, US
Ziad Sahab - Fairfax VA, US
Assignee:
GEORGETOWN UNIVERSITY - Washington DC
International Classification:
C07C 235/84
A61K 31/357
A61K 45/06
A61K 31/196
C07D 307/66
A61K 31/341
C07D 213/56
A61K 31/4406
C07D 409/14
A61K 31/4436
C07K 5/065
A61K 38/05
A61K 31/4155
C07D 403/04
A61K 31/4178
C07D 317/46
US Classification:
514 177, 549439, 514465, 562457, 514563, 549487, 514472, 546335, 514357, 5462804, 514336, 562433, 514 193, 514 2191, 5483641, 514406, 5483134, 514386
Abstract:
Small molecule inhibitors of AGBL2 are provided, as well as methods of using the inhibitors to treat or prevent cancer and neurologic disorders.