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Zhizhen Z Zheng

from Skillman, NJ
Age ~58

Zhizhen Zheng Phones & Addresses

  • Skillman, NJ
  • Cheshire, CT
  • 103 Putter Dr, Wallingford, CT 06492
  • Pittsburgh, PA
  • Gaithersburg, MD
  • New Haven, CT
  • Rockville, MD

Publications

Us Patents

Macrocyclic Isoquinoline Peptide Inhibitors Of Hepatitis C Virus

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US Patent:
7173004, Feb 6, 2007
Filed:
Apr 16, 2004
Appl. No.:
10/825693
Inventors:
Fiona McPhee - Wallingford CT, US
Jeffrey Allen Campbell - Glen Gardner NJ, US
Stanley D'Andrea - Meriden CT, US
Zhizhen Barbara Zheng - Cheshire CT, US
Andrew Charles Good - Wallingford CT, US
David J. Carini - Wallingford CT, US
Barry L. Johnson - Wallingford CT, US
Paul Michael Scola - Glastonbury CT, US
Kenneth M. Boy - Durham CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 38/00
US Classification:
514 10
Abstract:
Macrocyclic isoquinoline peptides are disclosed having the general formula:A compound of formula I:wherein Rto R, Q and W are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Hepatitis C Virus Inhibitors

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US Patent:
7741281, Jun 22, 2010
Filed:
Nov 1, 2006
Appl. No.:
11/591253
Inventors:
Stanley D'Andrea - Wallingford CT, US
Zhizhen Barbara Zheng - Cheshire CT, US
Jeffrey Allen Campbell - Glen Gardner NJ, US
Fiona McPhee - Wallingford CT, US
Andrew Charles Good - Wallingford CT, US
Paul Michael Scola - Glastonbury CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 38/00
US Classification:
514 9
Abstract:
Macrocyclic peptides are disclosed having the general formula:.

Hepatitis C Virus Inhibitors

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US Patent:
7772183, Aug 10, 2010
Filed:
Oct 11, 2006
Appl. No.:
11/546505
Inventors:
David J. Carini - Wallingford CT, US
Barry L. Johnson - Wallingford CT, US
Zhizhen Barbara Zheng - Cheshire CT, US
Stanley D'Andrea - Wallingford CT, US
Paul Michael Scola - Glastonbury CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 38/00
US Classification:
514 9
Abstract:
Hepatitis C virus inhibitors having the general formula.

Inhibitors Of Hepatitis C Virus

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US Patent:
8343477, Jan 1, 2013
Filed:
Oct 25, 2007
Appl. No.:
11/923918
Inventors:
Stanley D'Andrea - Wallingford CT, US
Zhizhen Barbara Zheng - Cheshire CT, US
Paul Michael Scola - Glastonbury CT, US
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 38/12
A61K 38/21
A61K 38/20
C07K 7/00
A61P 31/12
US Classification:
424 854, 424 852, 424 857, 514 43, 514 9, 530317
Abstract:
Macrocyclic peptides are disclosed having the general formula:wherein R, R′, R, R, R′, X, Q and W are described. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.

Novel Isoxazolinone Antibacterial Agents

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US Patent:
20020094984, Jul 18, 2002
Filed:
Feb 13, 2001
Appl. No.:
09/782120
Inventors:
Lawrence Snyder - Clinton CT, US
Zhizhen Zheng - Cheshire CT, US
International Classification:
C07D413/02
A61K031/5377
A61K031/495
A61K031/454
A61K031/4747
A61K031/42
US Classification:
514/236800, 514/254040, 514/326000, 514/380000, 514/278000, 544/137000, 544/367000, 546/016000, 546/208000, 548/243000
Abstract:
This invention describes isoxazolinone derivatives which possess antibacterial activity and are useful in the treatment of bacterial diseases. More particularly, new isoxazolinones are provided having the general formula wherein A and Rare as described in the specification.

Inhibitors Of Human Immunodeficiency Virus Replication

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US Patent:
20140051692, Feb 20, 2014
Filed:
Aug 5, 2013
Appl. No.:
13/959268
Inventors:
Manoj Patel - Berlin CT, US
Stanley D'Andrea - Wallingford CT, US
Zhizhen Barbara Zheng - Cheshire CT, US
Timothy P. Connolly - Portland CT, US
David R. Langley - Meriden CT, US
Kevin Peese - Haddam CT, US
Zhongyu Wang - Tolland CT, US
Michael A. Walker - Durham CT, US
John F. Kadow - Wallingford CT, US
International Classification:
A61K 31/5383
A61K 45/06
C07D 491/22
C07D 498/22
A61K 31/519
US Classification:
5142295, 540472, 514257, 540469
Abstract:
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.

Aminopyrrolotriazines As Kinase Inhibitors

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US Patent:
20200347071, Nov 5, 2020
Filed:
Jan 24, 2019
Appl. No.:
16/963886
Inventors:
- Princeton NJ, US
Murugaiah Andappan Murugaiah Subbaiah - Hosur, IN
Carolyn Diane Dzierba - Middletown CT, US
Hua Gong - King of Prussia PA, US
Jason M. Guernon - Pipersville PA, US
Junqing Guo - Princeton NJ, US
Amy C. Hart - Ewing NJ, US
Guanglin Luo - Madison CT, US
John E. Macor - Washington Crossing PA, US
William J. Pitts - Newtown PA, US
Jianliang Shi - Furlong PA, US
Brian Lee Venables - Durham CT, US
Carolyn A. Weigelt - Langhorne PA, US
Yong-Jin Wu - Madison CT, US
Zhizhen Barbara Zheng - Cheshire CT, US
Jie Chen - Cambridge MA, US
International Classification:
C07D 487/04
Abstract:
The disclosure relates to compounds of formula I which are useful as kinase modulators including RIPK 1 modulation. The disclosure also provides methods of making and using the compounds for example in treatments related to necrosis or inflammation as well as other indications.

Pyridin-3-Yl Acetic Acid Derivatives As Inhibitors Of Human Immunodeficiency Virus Replication

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US Patent:
20190127351, May 2, 2019
Filed:
May 9, 2017
Appl. No.:
16/094536
Inventors:
- Brenford, Middlesex, GB
B. Narasimhulu NAIDU - Wallingford CT, US
Manoj PATEL - Wallingford CT, US
Michael A. WALKER - Wallingford CT, US
Tao WANG - Wallingford CT, US
Zhiwei YIN - Wallingford CT, US
Zhongxing ZHANG - Wallingford CT, US
Zhizhen Barbara ZHENG - Wallingford CT, US
International Classification:
C07D 401/14
C07D 401/04
C07D 405/14
A61K 31/5365
A61K 31/4725
A61K 31/4709
A61K 31/4545
C07D 409/14
C07D 413/14
C07D 411/14
A61P 31/18
Abstract:
Disclosed are compounds of Formula I, including pharmaceutically acceptable salts, pharmaceutical compositions comprising the compounds, methods for making the compounds and their use in inhibiting HIV integrase and treating those infected with HIV or AIDS.
Zhizhen Z Zheng from Skillman, NJ, age ~58 Get Report