US Patent:
20060099171, May 11, 2006
Inventors:
Masahide Tone - Media PA, US
Yukiko Tone - Media PA, US
International Classification:
C07H 21/04
C12P 21/02
A61K 39/395
C07K 14/525
US Classification:
424085100, 435069500, 435320100, 435325000, 530351000, 530350000, 536023500, 424145100
Abstract:
The present invention provides mGITRL proteins, nucleotide molecules encoding same, mGITRL messenger RNA molecules, methods of expressing a recombinant gene in an immune cell and of stimulating CD4+CD25− T cells, comprising same or comprising agonist anti-GITR antibodies