Yuan An Liu

20130260455, Oct 3, 2013

Mar 1, 2013

13/782671

Timothy Charles Hoey - Hillsborough CA, US
Edward Thein Htun van der Horst - Palo Alto CA, US
Aaron Ken Sato - Burlingame CA, US
Yuan Ching Liu - Fremont CA, US
Maureen Fitch Bruhns - San Mateo CA, US
John A. Lewicki - Los Gatos CA, US

OncoMed Pharmaceuticals, Inc. - Redwood City CA

C07K 16/28

435331, 536 2353, 4353201, 43525233, 43525231, 4352542

The present invention relates to Notch-binding agents and Notch antagonists and methods of using the agents and/or antagonists for treating diseases such as cancer. The present invention provides antibodies that specifically bind to a non-ligand binding region of the extracellular domain of one or more human Notch receptor, such as Notch2 and/or Notch3, and inhibit tumor growth. The present invention further provides methods of treating cancer, the methods comprising administering a therapeutically effective amount of an antibody that specifically binds to a non-ligand binding region of the extracellular domain of a human Notch receptor protein and inhibits tumor growth.

20130296536, Nov 7, 2013

Mar 14, 2013

13/826432

Timothy Charles Hoey - Hillsborough CA, US
Edward Thein Htun van der Horst - Palo Alto CA, US
Aaron Ken Sato - Burlingame CA, US
Yuan Ching Liu - Fremont CA, US
Maureen Fitch Bruhns - San Mateo CA, US
John A. Lewicki - Los Gatos CA, US

C07K 16/22

5303873, 5303879

The present invention relates to Notch-binding agents and Notch antagonists and methods of using the agents and/or antagonists for treating diseases such as cancer. The present invention provides antibodies that specifically bind to a non-ligand binding region of the extracellular domain of one or more human Notch receptor, such as Notch2 and/or Notch3, and inhibit tumor growth. The present invention further provides methods of treating cancer, the methods comprising administering a therapeutically effective amount of an antibody that specifically binds to a non-ligand binding region of the extracellular domain of a human Notch receptor protein and inhibits tumor growth.

48791270, Nov 7, 1989

Nov 1, 1988

7/266338

Yuan K. Liu - Concord CA
Philip A. Kuhmichel - Antioch CA
Fred G. Cordes - Oakland CA
Wayman Wong - Concord CA

Del Monte Corporation - San Francisco CA

A23B 704
A23B 708
A23L 310

426325

A process for storing produce for extended periods of time prior to further processing by canning or the like, which comprises the steps of immersing the produce in a substantially isotonic aqueous storage solution, wherein the solutes content of the storage solution is adjusted such that the osmotic pressures of the produce and the storage solution are substantially equal. The storage solution preferably comprises an edible sugar, an edible organic acid, and an edible oxygen scavenger. The produce is than stored in the solution at a temperature below about 40. degree. F. and subsequently canned and sterilized.

46146598, Sep 30, 1986

Apr 1, 1985

6/718790

Yuan K. Liu - Concord CA

Del Monte Corporation - San Francisco CA

A23B 700

426321

The crowns of mature pineapples ready for harvest are treated with an aqueous medium containing sufficient amounts of a gibberellin to retard withering and senescense of the crowns. The medium is preferably applied to the crowns soon after the pineapples have been harvested. The pineapples treated in accordance with this invention retain a freshly harvested appearance for an extended period of time and make them ideally suited for sale in the fresh fruit market.

47103884, Dec 1, 1987

Jul 25, 1986

6/889433

Yuan K. Liu - Concord CA

Del Monte Corporation - San Francisco CA

A23B 700

426102

The crowns of mature pineapples ready for harvest are treated with an aqueous medium containing sufficient amounts of a gibberellin to retard withering and senescense of the crowns. The medium is preferably applied to the crowns soon after the pineapples have been harvested. The pineapples treated in accordance with this invention retain a freshly harvested appearance for an extended period of time and make them ideally suited for sale in the fresh fruit market.

20220359062, Nov 10, 2022

Sep 11, 2020

17/620445

- Mountain View CA, US
Ayush Jain - Los Altos CA, US
Peggy Yen Phuong Bui - San Francisco CA, US
Clara Eng - San Carlos CA, US
David Henry Way - Redwood City CA, US
Kang Li - Sunnyvale CA, US
Vishakha Gupta - Sunnyvale CA, US
Jessica Gallegos - San Francisco CA, US
Dennis Ai - Redwood City CA, US
Yun Liu - Mountain View CA, US
David Coz - Mountain View CA, US
Yuan Liu - Santa Clara CA, US

G16H 30/40
G16H 50/20
G16H 10/60

The present disclosure is directed to a deep learning system for differential diagnoses of skin diseases. In particular, the system performs a method that can include obtaining a plurality of images that respectively depict a portion of a patient's skin. The method can include determining, using a machine-learned skin condition classification model, a plurality of embeddings respectively for the plurality of images. The method can include combining the plurality of embeddings to obtain a unified representation associated with the portion of the patient's skin. The method can include determining, using the machine-learned skin condition classification model, a skin condition classification for the portion of the patients skin, the skin condition classification produced by the machine-learned skin condition classification model by processing the unified representation, wherein the skin condition classification identifies one or more skin conditions selected from a plurality of potential skin conditions.

20220268565, Aug 25, 2022

Apr 4, 2022

17/713044

- Dublin CA, US
- Jena, DE
Yuan LIU - Dublin CA, US

G01B 9/02004
G01B 9/02001
G01B 9/02
G01B 9/02091
H01S 5/062
H01S 5/024

Various optical systems equipped with diode laser light sources are discussed in the present application. One example system includes a diode laser light source for providing a beam of radiation. The diode laser has a spectral output bandwidth when driven under equilibrium conditions. The system further includes a driver circuit to apply a pulse of drive current to the diode laser. The pulse causes a variation in the output wavelength of the diode laser during the pulse such that the spectral output bandwidth is at least two times larger than the spectral output bandwidth under the equilibrium conditions.

20210369109, Dec 2, 2021

Sep 24, 2019

17/277177

- Dublin CA, US
- Jena, DE
Yuan LIU - Dublin CA, US
Matthew J. EVERETT - Livermore CA, US

A61B 3/12
A61B 3/00
A61B 3/15

A low cost fundus camera uses LED light sources placed adjacent the camera's imaging stop, and thereby eliminates the need for optics for introducing the light source to the camera's optical path. Lens reflex in the pupil relay is avoided by using only reflective optics in the pupil relay. Reflex from the LEDs is mitigated by actuating each LED separately, one at a time, and capturing a separate image with each actuated LED. Reflex-free regions of each captured image are extracted and combined to create a composite, reflex-free image.