US Patent:
20100144558, Jun 10, 2010
Inventors:
Frederic Zenhausern - Fountain Hills AZ, US
Christine Orozco - Mystic CT, US
Mark Richards - Maricopa AZ, US
Carl Yamashiro - Chandler AZ, US
Sally A. Amundson - New York NY, US
Ralf Lenigk - Tempe AZ, US
Michael L. Bittner - Phoenix AZ, US
Yoganand Balagurunathan - Tempe AZ, US
International Classification:
C40B 60/12
Abstract:
Exposure to ionizing radiation can produce a well-defined dose dependent signature in terms of changes in gene expression. In approaches and devices described herein, such a signature can be used to generate and use a self-contained radiation biodosimeter device, based on, for example, a blood finger stick. Various aspects of the invention are directed to biodosimetry with a fully integrated biochip using gene expression signatures.