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Yinges Yigzaw

from Newbury Park, CA
Age ~56
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Also known as:
Yigzaw Y Yinges, Ynges Yigzaw, Yinge Yigzaw, Yinges Httpwwwdiabe Yigzaw, S W, S S, S N
Related to:
Mulualem Y TeferiMulualem Teferi, 42
Connected to:
Destaw Yigzaw, 49Jennifer Yih, 35Jimmy Yih, 33Kien C Yih, 47Ong Yih, 35Wen C Yih, 50Yuehwern Yih, 61Hai D Yihai, 52Hung S Yii, 59Michael Y Yii, 58

Yinges Yigzaw Phones & Addresses

  • Newbury Park, CA
  • Gustine, TX
  • San Ramon, CA
  • 1814 26Th St, Issaquah, WA 98029 (425) 427-1631
  • Bellevue, WA
  • 1018 Oakmont Pl, Memphis, TN 38107 (901) 276-2267 (901) 276-1242
  • Seattle, WA
  • 1850 Via Petirrojo APT B, Newbury Park, CA 91320

Work

Company: Amgen Position: Sr scientist

Education

School / High School: Katholieke Universiteit Leuven 1992 to 1997

Skills

Protein Purification • Protein Engineering • Pcr • Lifesciences • Lc Ms • Transfection

Industries

Biotechnology

Resumes

Resumes

Yinges Yigzaw Photo 1

Senior Principal Scientist

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Location:
San Francisco, CA
Industry:
Biotechnology
Work:
Amgen
Sr Scientist
Education:
Katholieke Universiteit Leuven 1992 - 1997
Skills:
Protein Purification
Protein Engineering
Pcr
Lifesciences
Lc Ms
Transfection

Publications

Us Patents

Method For Using Light Scattering In Real Time To Directly Monitor And Control Impurity Removal In Purification Processes

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US Patent:
20130303732, Nov 14, 2013
Filed:
Mar 26, 2013
Appl. No.:
13/850664
Inventors:
Duke H. Phan - Kenmore WA, US
Yinges Yigzaw - Issaquah WA, US
Robert Bailey - Bothell WA, US
International Classification:
G01N 33/68
C07K 16/00
US Classification:
5303871, 436 86, 436 87
Abstract:
The invention provides a method for controlling contaminants in biopharmaceutical purification processes by using light scattering and UV absorbance to establish a determinant. The invention makes use of multi-angle light scattering (MALS) and UV as a continuous monitoring system to provide information about the elution peak fractions in real-time instead of conventional pooling methods that rely on a predetermined percent UV peak max value to initiate the pooling process; regardless of product quality.

Methods Of Reducing The Enzymatic Hydrolysis Activity Rate In A Composition Obtained From A Purification Platform

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US Patent:
20220194980, Jun 23, 2022
Filed:
Nov 2, 2021
Appl. No.:
17/517531
Inventors:
- South San Francisco CA, US
- Little Falls NJ, US
Alexandra Thomas Morris - Pacifica CA, US
Bernhard Spensberger - Eberfing, DE
Yinges Yigzaw - San Ramon CA, US
Franziska Edelmann - Wolfratshausen, DE
Roberto Falkenstein - Munich, DE
Tobias Graf - Penzberg, DE
Jie Gu - Thousand Oaks CA, US
Jeevan Prabhakar - San Francisco CA, US
International Classification:
C07K 1/22
C07K 1/34
C07K 1/36
A61K 39/395
C07K 1/20
C07K 1/16
B01D 15/32
B01D 15/38
B01D 61/14
B01D 15/36
B01D 39/20
B01D 39/16
Abstract:
The present disclosure provides purification platforms comprising a depth filter step and/or a hydrophobic interaction chromatography (HIC) step. Also disclosed herein are methods of using the purification platforms described herein and compositions obtained therefrom, such as pharmaceutical compositions.

Method For Using Light Scattering In Real Time To Directly Monitor And Control Impurity Removal In Purification Processes

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US Patent:
20200018771, Jan 16, 2020
Filed:
Sep 23, 2019
Appl. No.:
16/579220
Inventors:
- Thousand Oaks CA, US
Duke H. PHAN - Kenmore WA, US
Yinges YIGZAW - Issaquah WA, US
Robert BAILEY - Bothell WA, US
Assignee:
AMGEN INC. - Thousand Oaks CA
International Classification:
G01N 33/68
C07K 16/00
Abstract:
The invention provides a method for controlling contaminants in biopharmaceutical purification processes by using light scattering and UV absorbance to establish a determinant. The invention makes use of multi-angle light scattering (MALS) and UV as a continuous monitoring system to provide information about the elution peak fractions in real-time instead of conventional pooling methods that rely on a predetermined percent UV peak max value to initiate the pooling process; regardless of product quality.

Purification Of Multispecific Antibodies

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US Patent:
20190256556, Aug 22, 2019
Filed:
Dec 14, 2018
Appl. No.:
16/221369
Inventors:
- South San Francisco CA, US
Eva ROSENBERG - Basel, CH
Bernard SALLIER - Basel, CH
Susanne KONRAD - Basel, CH
Wolfgang KOEHNLEIN - Basel, CH
Steffen WILLMANN - Basel, CH
Agathe BIALAS - Basel, CH
Kimberly Ann KALEAS-CARROLL - South San Francisco CA, US
Yinges YIGZAW - South San Francisco CA, US
Assignee:
Genentech, Inc. - South San Francisco CA
International Classification:
C07K 1/36
C07K 1/16
C07K 1/34
C07K 1/18
C07K 16/46
A61P 27/02
C07K 16/22
C07K 16/26
Abstract:
The present invention provides methods of purifying multispecific antibodies. The methods comprise the sequential steps of performing a capture chromatography, a first mixed mode chromatography and a second mixed mode chromatography. In some aspects, the invention provides compositions of multispecific antibodies, which compositions have reduced levels of one or more product-specific impurities and/or process-specific impurities.
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Yinges Yigzaw from Newbury Park, CA, age ~56 Get Report