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Vittorio Sartorelli

from Bethesda, MD
Age ~66

Vittorio Sartorelli Phones & Addresses

  • 6300 Hollins Dr, Bethesda, MD 20817 (301) 581-0357
  • Los Angeles, CA
  • South Pasadena, CA
  • San Gabriel, CA
  • Palo Alto, CA

Public records

Vehicle Records

Vittorio Sartorelli

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Address:
6300 Hollins Dr, Bethesda, MD 20817
VIN:
4JGBB2FB7AA537270
Make:
Mercedes-Benz
Model:
M-Class
Year:
2010

Publications

Us Patents

Methods Of Using Deacetylase Inhibitors To Promote Cell Differentiation And Regeneration

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US Patent:
7795208, Sep 14, 2010
Filed:
May 4, 2007
Appl. No.:
11/800151
Inventors:
Vittorio Sartorelli - Bethesda MD, US
Pier Lorenzo Puri - San Diego CA, US
Assignee:
The Salk Institute for Biological Study - La Jolla CA
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A61K 38/00
A61K 31/557
A61K 31/165
US Classification:
514 2, 514 12, 514574, 514619
Abstract:
A method of enhancing progenitor cell differentiation, including enhancing myogenesis, neurogenesis, and hematopoiesis, by contacting a progenitor cell with an effective amount of a deacetylase inhibitor (DI). The progenitor cell can be part of cell culture, such as a cell culture used for in vitro or in vivo analysis of progenitor cell differentiation, or can be part of an organism, such as a human or other mammal. Contacting the progenitor cell with a DI can lead to enhancement of expression of terminal cell-type specific genes in the progenitor cell, such as enhancing expression of muscle-specific genes in myoblasts. Administering a DI to a subject also can provide some prophylactic or therapeutic effect for inhibiting, preventing, or treating associated with a degeneration or loss of tissue. The DI can be administered to a subject as part of a pharmaceutical composition.

Methods Of Using Deacetylase Inhibitors To Promote Cell Differentiation And Regeneration

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US Patent:
20050054091, Mar 10, 2005
Filed:
Oct 17, 2002
Appl. No.:
10/492901
Inventors:
Vittorio Sartorelli - Bethesda MD, US
Pier Puri - San Diego CA, US
International Classification:
C12N005/08
US Classification:
435366000
Abstract:
A method of enhancing progenitor cell differentiation, including enhancing myogenesis, neurogenesis, and hematopoiesis, by contacting a progenitor cell with an effective amount of a deacetylase inhibitor (DI). The progenitor cell can be part of cell culture, such as a cell culture used for in vitro or in vivo analysis of progenitor cell differentiation, or can be part of an organsism, such as a human or other mammal. Contacting the progenitor cell with a DI can lead to enhancement of expression of terminal cell-type specific genes in the progenitor cell, such as enhancing expression of muscle-specific genes in myoblasts. Administering a DI to a subject also can provide some prophylactic or therapeutic effect for inhibiting, preventing, or treating associated with a degeneration or loss of tissue. The DI can be administered to a subject as part of a pharmaceutical composition.
Vittorio Sartorelli from Bethesda, MD, age ~66 Get Report