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Valter D Longo

from Playa del Rey, CA
Age ~56

Valter Longo Phones & Addresses

  • 8240 Zitola Ter, Playa del Rey, CA 90293 (310) 439-2649
  • Venice, CA
  • Los Angeles, CA
  • 8240 Zitola Ter, Playa del Rey, CA 90293

Work

Position: Professional/Technical

Education

Degree: High school graduate or higher

Business Records

Name / Title
Company / Classification
Phones & Addresses
Valter Longo
President
DSR PHARMACEUTICALS INC
Mfg Pharmaceutical Preparations
3975 Osborne St, Culver City, CA 90232
8240 Zitola Ter, Venice, CA 90293

Publications

Us Patents

Genes, Mutations, And Drugs That Increase Cellular Resistance To Damage And Extend Longevity In Organisms From Yeast To Humans

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US Patent:
20030044946, Mar 6, 2003
Filed:
Apr 3, 2002
Appl. No.:
10/116722
Inventors:
Valter Longo - Los Angeles CA, US
International Classification:
C12N009/99
C07H021/04
A61K048/00
US Classification:
435/184000, 514/044000, 536/023200
Abstract:
In accordance with the present invention there is disclosed a complete molecular pathway that regulates aging and longevity in yeast and evidence for the conservation of this pathway and mechanisms in organisms ranging from yeast to humans. This invention also identifies novel molecular mechanisms of aging in eukaryotes and provides new compositions and methods for the development of drugs that prevent and treat diseases and disorders associated with aging and extend the life-span of humans.

Method Of Treating Conditions Caused By Activated Microglia

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US Patent:
20030152646, Aug 14, 2003
Filed:
Dec 11, 2002
Appl. No.:
10/316372
Inventors:
Valter Longo - Los Angeles CA, US
Caleb Finch - Altadena CA, US
Zhong Xie - Los Angeles CA, US
International Classification:
A61K033/00
US Classification:
424/718000
Abstract:
This invention provides methods of preventing neurotoxicity by activated microglia. A method of treating a medical condition in a subject is provided, wherein said condition is affected by the presence of neurotoxins such as peroxynitrite or TNF-, said method comprising administering to the subject a compound that decomposes peroxynitrite or inhibits TNF- secretion but does not affect normal activity of microglia, wherein the decomposition of peroxynitrite alone is sufficient to alleviate the pathology of said condition. The method of this invention may be used in conjunction with the administration of a vaccine that increases the microglial activity of clearing A

Induction Of Differential Stress Resistance And Uses Thereof

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US Patent:
20080242638, Oct 2, 2008
Filed:
Mar 28, 2008
Appl. No.:
12/058600
Inventors:
Valter Longo - Playa del Rey CA, US
Assignee:
University of Southern Carlifornia - Los Angeles CA
International Classification:
A61K 31/675
A61K 31/40
A61P 35/00
US Classification:
514 90, 514419
Abstract:
This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents.

Dietary Compositions And Methods For Protection Against Chemotherapy, Radiotherapy, Oxidative Stress, And Aging

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US Patent:
20100004309, Jan 7, 2010
Filed:
Apr 24, 2009
Appl. No.:
12/430058
Inventors:
Valter Longo - Los Angeles CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
A61K 31/405
A61P 3/02
US Classification:
514419
Abstract:
The present invention relates to dietary compositions comprising reduced level of methionine, tryptophan, all amino acids, or protein, dietary compositions comprising glycerol as a substitute for monosaccharides, disaccharides, and polysaccharides, and hypocaloric or calorie free diets with reduced level of energy, carbohydrates, or protein. Also disclosed are methods of using these compositions and diets, as well as fasting, to protect subjects against chemotherapy, radiotherapy, oxidative stress, or aging.

Methods And Nutritional Formulations To Increase The Efficacy And Reduce The Side Effects Of Cancer Treatment

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US Patent:
20110118528, May 19, 2011
Filed:
Oct 22, 2010
Appl. No.:
12/910508
Inventors:
Valter D. Longo - Playa del Rey CA, US
Changhan Lee - Los Angeles CA, US
Assignee:
UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA
International Classification:
A61N 5/00
A61K 31/704
A61K 31/675
A61K 31/7068
A61K 31/282
A61K 31/337
A61K 31/513
A61K 31/255
A61K 33/24
A61P 35/00
A61K 31/20
G09B 19/00
US Classification:
600 1, 514 34, 514110, 514 49, 514492, 514449, 514274, 514517, 424649, 514558, 434127
Abstract:
The present invention relates to methods of protecting patients and sensitizing cancer cells in combination with chemotherapy and/or radiation therapy. More specifically, the invention provides nutritional methods and formulations that are capable of reducing cancer growth without causing chronic weight loss in patients, protecting normal cells, tissues and organs from chemotherapy and/radiation therapy, and sensitizing cancer cells against low, normal and high-dose chemotherapy. Some of the methods also impede cancer growth even without chemotherapy.

Induction Of Differential Stress Resistance And Uses Thereof

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US Patent:
20120329712, Dec 27, 2012
Filed:
Jun 5, 2012
Appl. No.:
13/488590
Inventors:
Valter Longo - Playa del Rey CA, US
Assignee:
University of Southern California - Los Angeles CA
International Classification:
A61K 31/255
A61K 38/14
A61P 35/00
A61K 31/7048
A61K 31/704
A61K 38/30
A61K 31/122
A61K 31/675
US Classification:
514 87, 514517, 514682, 514 209, 514 90, 514 27, 514 34, 514 193
Abstract:
This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents.

Growth Hormone Receptor Deficiency Causes A Major Reduction In Pro-Aging Signaling, Cancer And Diabetes In Humans

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US Patent:
20130045215, Feb 21, 2013
Filed:
Jan 21, 2011
Appl. No.:
13/643673
Inventors:
Valter D. Longo - Playa del Rey CA, US
Jaime Guevara - Aventura FL, US
Assignee:
UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA
International Classification:
A61K 39/395
A61K 38/27
C12N 5/071
A61K 38/16
US Classification:
4241581, 514 113, 4241721, 514 114, 435375
Abstract:
A method for alleviating a symptom of chemotherapy in a subject comprises identifying a subject undergoing chemotherapy and then administering a therapeutically effective amount of a GH/IGF-1 Axis inhibitory composition to the subject. Typically, the levels of IGF-1 and/or GH in the subject are monitored as well as chemotherapy related symptoms. A method of alleviating oxidative damage, cellular damage including mutations, and insulin resistance in a subject is also provided.

Growth Hormone Receptor Deficiency Causes A Major Reduction In Pro-Aging Signaling, Cancer And Diabetes In Humans

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US Patent:
20130316948, Nov 28, 2013
Filed:
Feb 8, 2012
Appl. No.:
13/982307
Inventors:
Valter D. Longo - Playa del Rey CA, US
Assignee:
UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA
International Classification:
G01N 33/68
G01N 33/53
US Classification:
514 76, 506 9, 436501, 435 792
Abstract:
A method for alleviating a symptom of chemotherapy in a subject comprises identifying a subject undergoing chemotherapy and then administering a therapeutically effective amount of a GH/IGF-1 Axis inhibitory composition to the subject. Typically, the levels of IGF-1 and/or GH in the subject are monitored as well as chemotherapy related symptoms. A method of alleviating oxidative damage, cellular damage including mutations, and insulin resistance in a subject is also provided.
Valter D Longo from Playa del Rey, CA, age ~56 Get Report