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Trevor Mcmorris Phones & Addresses

  • 8911 Nottingham Pl, La Jolla, CA 92037 (858) 453-1785
  • Escondido, CA
  • San Diego, CA
  • Oceanside, CA
  • 8911 Nottingham Pl, La Jolla, CA 92037

Work

Position: Production Occupations

Publications

Us Patents

Total Synthesis Of Antitumor Acylfulvenes

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US Patent:
6469184, Oct 22, 2002
Filed:
Jun 5, 2001
Appl. No.:
09/874839
Inventors:
Trevor C. McMorris - La Jolla CA
Assignee:
Regents of the University of California - Oakland CA
International Classification:
C07D31772
US Classification:
549341, 549339
Abstract:
The present invention provides a method of synthesizing compounds of formula (I): wherein R and Râ are independently (C -C )alkyl.

Antitumor Agents

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US Patent:
6548679, Apr 15, 2003
Filed:
Aug 17, 2000
Appl. No.:
09/641191
Inventors:
Trevor C. McMorris - La Jolla CA
Michael J. Kelner - La Jolla CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 315375
US Classification:
548407, 5142375, 5142388, 514278, 514423, 514681, 544 70, 544173, 546 15, 548411, 568303, 568305, 568306, 568327
Abstract:
The present invention provides compounds of general formula I or II: wherein R , R , R , R , R , R , and R have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising compounds of formula I or II, intermediates and processes useful for preparing compounds of formula I or II, and methods comprising inhibiting tumor growth or treating cancer by administering one or more compounds of formula I or II.

Total Synthesis Of Antitumor Acylfulvenes

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US Patent:
6717017, Apr 6, 2004
Filed:
Aug 30, 2002
Appl. No.:
10/231575
Inventors:
Trevor C. McMorris - La Jolla CA
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
C07C 3537
US Classification:
568373, 568374, 568377, 568379, 568817, 568819, 568823
Abstract:
The present invention provides a method of synthesizing compounds of formula (I) or (II): wherein R is hydrogen, Râ is (C -C )alkyl and X is a hydroxyl protecting group.

Antitumor Agents

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US Patent:
6855696, Feb 15, 2005
Filed:
Nov 5, 2001
Appl. No.:
10/013009
Inventors:
Trevor C. McMorris - La Jolla CA, US
Michael J. Kelner - La Jolla CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K038/05
A61K038/06
US Classification:
514 18, 514 19, 514681, 514691, 530330, 530331, 568306, 568327
Abstract:
The present invention provides illudin analogs of the general formula I: wherein R, R, R, R, R, and Rhave any of the values defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising compounds of formula I, intermediates and processes useful for preparing compounds of formula I, and methods comprising inhibiting tumor growth or treating cancer by administering one or more compounds of formula I.

Antitumor Agents

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US Patent:
6908918, Jun 21, 2005
Filed:
Apr 14, 2003
Appl. No.:
10/413449
Inventors:
Trevor C. McMorris - La Jolla CA, US
Michael J. Kelner - La Jolla CA, US
Assignee:
Regents of the University of California - Oakland CA
International Classification:
A61K031/122
A61K031/5375
C07D265/30
C07D295/02
US Classification:
5142312, 514462, 514691, 544107, 549336, 568373
Abstract:
The present invention provides compounds of general formula I or II: wherein R, R, R, R, R, R, and Rhave any of the values defined in the specification, and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising compounds of formula I or II, intermediates and processes useful for preparing compounds of formula I or II, and methods comprising inhibiting tumor growth or treating cancer by administering one or more compounds of formula I or II.

Antitumor Agents

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US Patent:
7141603, Nov 28, 2006
Filed:
Jun 13, 2005
Appl. No.:
11/151013
Inventors:
Trevor C. McMorris - La Jolla CA, US
Michael J. Kelner - La Jolla CA, US
Assignee:
The Regents of The University California - Oakland CA
International Classification:
A61K 31/335
C07D 317/72
C07C 49/453
US Classification:
514462, 549339, 568373
Abstract:
The present invention provides compounds of general formula I or II:.

Antitumor Agents

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US Patent:
7629380, Dec 8, 2009
Filed:
Nov 16, 2006
Appl. No.:
11/600375
Inventors:
Trevor C. McMorris - La Jolla CA, US
Michael J. Kelner - La Jolla CA, US
Assignee:
The Regents of The University of California - Oakland CA
International Classification:
A61K 31/335
C07D 317/72
C07C 49/453
US Classification:
514462, 549339, 568373
Abstract:
The present invention provides compounds of the general formula I:.

Illudin Analogs Useful As Anticancer Agents

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US Patent:
7655695, Feb 2, 2010
Filed:
Aug 3, 2006
Appl. No.:
11/997432
Inventors:
Trevor C. McMorris - La Jolla CA, US
Michael J. Kelner - La Jolla CA, US
Assignee:
The Regents of The University of California - Oakland CA
International Classification:
A61K 31/27
A61K 31/17
A61K 31/13
C07C 271/18
C07C 271/22
C07C 239/14
C07C 239/18
C07C 275/22
C07C 275/24
C07C 335/10
US Classification:
514479, 514480, 514645, 514580, 514588, 514595, 560115, 560119, 564 17, 564 56, 564 57, 564300
Abstract:
Acylfulvene analogs, which inhibit tumor growth, especially solid tumor growth, and which have an adequate therapeutic index to be effective for in vivo treatment are provided herein. The compounds described herein are useful as anti-neoplastic agents, i. e. , to inhibit tumor cell growth in vitro or in vivo, in mammalian hosts, such as humans or animals, e. g. , domestic animals, and are effective against solid tumors, hematologic malignancies and multi-drug resistant cancers/tumors. The present compounds can be used alone or they can be used in combination with one or more anti-cancer or anti-tumor agents.

Wikipedia

Irofulven

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The compound was oringally synthesized by Dr. Trevor McMorris (UCSD) and found to have anticancer properties by Dr. Michael J Kelner (UCSD). ...

Trevor C Mcmorris from La Jolla, CA, age ~95 Get Report