US Patent:
20030059808, Mar 27, 2003
Inventors:
Jun S. Liu - Weston MA, US
Zhaohui Steve Qin - Somerville MA, US
Tianhua Niu - West Roxbury MA, US
International Classification:
C12Q001/68
G06F019/00
G01N033/48
G01N033/50
Abstract:
Haplotypes for phased genotypic information are determined from unphased genotypic information. One exemplary method includes separating a dataset that includes genotypic information for a plurality of markers for each of a plurality of individuals into subdatasets, each subdataset including the genotypic information for a subset of the plurality of markers; for each subdataset, identifying haplotypes compatible with marker information for each marker of the subset and for each individual of the plurality; and for each individual, assembling the haplotypes from each of the subsets to provide the individual's haplotype with respect to the plurality of markers.