Thomas E Dambra

6448406, Sep 10, 2002

Aug 9, 2000

09/634775

Thomas E. DAmbra - Wynantskill NY
Garry M. Pilling - East Nassau NY

Albany Molecular Research, Inc. - Albany NY

C07D21122

546239, 546240

The present invention relates to a method for preparing piperidine derivative compounds by converting, with a piperidine compound, regioisomers having the formula: where Z is âCG G G ; G , G , and G are the same or different and are selected from the group consisting of OR , SR , and NR R ; X is halogen, OR , SR , NR R , OSO R , or NHSO R ; R , R , R , and R are the same or different and are selected from the group consisting of hydrogen, an alkyl moiety, and an aryl moiety; and A is a substituent of its ring and is selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, alkoxy, and other substituents.

6452011, Sep 17, 2002

Aug 9, 2000

09/634169

Thomas E. DAmbra - Wynantskill NY
Garry M. Pilling - East Nassau NY

Albany Molecular Research, Inc. - Albany NY

C07D21134

546210, 546209, 546216, 546239, 546240, 544 34, 544 96, 544299, 540467, 540470, 540488, 540492

The present invention relates to a method for preparing piperidine derivative compounds by converting, with a piperidine compound, regioisomers having the formula: where Z is or and where m is 1 or 4-6; Q and Y are the same or different and are selected from the group consisting of O, S, and NR ; R and R are the same or different and are selected from the group consisting of hydrogen, an alkyl moiety, an aryl moiety, OR , SR , and NR R ; X is halogen, OR , SR , NR R , OSO R , or NHSO R ; R , R , R , R , and R are the same or different and are selected from the group consisting of hydrogen, an alkyl moiety, and an aryl moiety; and A is a substituent of its ring and is selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, alkoxy, and other substituents.

6458958, Oct 1, 2002

Aug 9, 2000

09/637127

Thomas E. DAmbra - Wynantskill NY
Garry M. Pilling - East Nassau NY

Albany Molecular Research, Inc. - Albany NY

C07D21134

546239, 546240

The present invention relates to a method for preparing piperidine derivative compounds by converting, with a piperidine compound, regioisomers having the formula: where Z is âCG G G ; G , G , and G are the same or different and are selected from the group consisting of OR , SR , and NR R ; and R and R are the same or different and are selected from the group consisting of hydrogen, an alkyl moiety, and an aryl moiety.

6797826, Sep 28, 2004

Sep 4, 2002

10/235052

Thomas E. DAmbra - Wynantskill NY

AMR Technology, Inc. - Manchester VT

C07D21122

546240, 546236, 546237, 546241

The present invention relates to substantially pure piperidine derivative compounds of the formulae: wherein R is hydrogen or hydroxy; R is hydrogen; or R and R taken together form a second bond between the carbon atoms bearing R and R ; R is âCOOH or âCOOR ; R has 1 to 6 carbon atoms; A, B, and D are the substituents of their respective rings each of which may be different or the same and are hydrogen, halogens, alkyl, hydroxy, alkoxy, or other substituents. A process of preparing such piperidine derivative compounds in substantially pure form is also disclosed.

6444824, Sep 3, 2002

Aug 9, 2000

09/634983

Thomas E. DAmbra - Wynantskill NY
Garry M. Pilling - East Nassau NY

Albany Molecular Research, Inc. - Albany NY

C07D21134

546210, 546209, 546216, 546239, 546240, 544 34, 544 96, 544299, 540469, 540470, 540488, 540492

The present invention relates to a method for preparing piperidine derivative compounds by converting, with a piperidine compound, regioisomers having the formula: where Z is and where m is 1 or 3-6; Q and Y are the same or different and are selected from the group consisting of O, S, and NR ; R and R are the same or different and are selected from the group consisting of hydrogen, an alkyl moiety, an aryl moiety, OR , SR , and NR R ; and R , R , and R are the same or different and are selected from the group consisting of hyrogen, an alkyl moiety, and an aryl moiety.