Inventors:
Kathy J. Maugh - Walnut CA
David M. Anderson - Rockville MD
Robert Strausberg - Silver Spring MD
Susan L. Strausberg - Silver Spring MD
Russ McCandliss - Gaithersburg MD
Tena Wei - Rockville MD
David Filpula - Gaithersburg MD
Assignee:
Genex Corporation - Gaithersburg MD
International Classification:
C12N 121
C12N 1512
C12N 119
C12N 1563
Abstract:
Vectors are provided that are capable of expressing, in microbial transformants, a protein having the native amino acid sequence of a bioadhesive precursor protein of a marine animal selected from the group consisting of mussels, barnacles, and oysters. The bioadhesive precursor protein can be expressed in transformants, recovered and converted to a bioadhesive protein by hydroxylation.