Search

Subbarao A Katragadda

from Cambridge, MA
Age ~67

Subbarao Katragadda Phones & Addresses

  • 20 Mcternan St APT 202, Cambridge, MA 02139 (908) 647-1888
  • 25 Hillcrest Way, Basking Ridge, NJ 07920 (908) 647-1888
  • 6 Raleigh Rd, Belmont, MA 02478 (617) 484-3853 (617) 484-9937 (617) 489-1617
  • 86 Hawthorne St, Belmont, MA 02478 (617) 484-3853
  • Somerset, NJ
  • Birmingham, AL
  • 25 Hillcrest Way, Basking Ridge, NJ 07920 (617) 852-0781

Work

Position: Sales Occupations

Education

Degree: High school graduate or higher

Publications

Us Patents

Therapeutic Guanidines

View page
US Patent:
6787569, Sep 7, 2004
Filed:
Aug 11, 2000
Appl. No.:
09/637512
Inventors:
Stanley M. Goldin - Lexington MA
James B. Fischer - Cambridge MA
Andrew Gannett Knapp - Salem MA
N. Laxma Reddy - Malden MA
David Berlove - Cambridge MA
Graham J. Durant - Marshfield MA
Subbarao Katragadda - Belmont MA
Sharad Magar - Somerville MA
Wenhong Fan - Boston MA
Elizabeth Yost - Waltham MA
Jun Qing Guo - Waltham MA
Assignee:
Cambridge NeuroScience, Inc. - Cambridge MA
International Classification:
A61K 31155
US Classification:
514634, 564237, 564238, 564239
Abstract:
The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines.

Therapeutic Guanidines

View page
US Patent:
7351743, Apr 1, 2008
Filed:
Aug 11, 2000
Appl. No.:
09/637774
Inventors:
Stanley M. Goldin - Lexington MA, US
James B. Fischer - Cambridge MA, US
Andrew Gannett Knapp - Salem MA, US
N. Laxma Reddy - Malden MA, US
David Berlove - Cambridge MA, US
Graham J. Durant - Marshfield MA, US
Subbarao Katragadda - Belmont MA, US
Sharad Magar - Somerville MA, US
Wenhong Fan - Boston MA, US
Elizabeth Yost - Waltham MA, US
Juo Qing Guo - Waltham MA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/155
C07C 279/18
US Classification:
514634, 564238, 564239
Abstract:
The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines.

Therapeutic Guanidines

View page
US Patent:
20070265348, Nov 15, 2007
Filed:
Jul 19, 2007
Appl. No.:
11/880199
Inventors:
Stanley Goldin - Lexington MA, US
James Fischer - Cambridge MA, US
Andrew Knapp - Salem MA, US
N. Laxma Reddy - Malden MA, US
David Berlove - Cambridge MA, US
Graham Durant - Cambridge MA, US
Subbarao Katragadda - Belmont MA, US
Sharad Magar - Somerville MA, US
Wenhong Fan - Rockey Hill CT, US
Elizabeth Yost - Waltham MA, US
Jun Qing Guo - Waltham MA, US
International Classification:
A61K 31/155
A61P 25/00
A61P 9/00
C07C 279/02
C07C 279/18
US Classification:
514634000, 564238000, 564241000
Abstract:
The present invention provides therapeutically useful substituted guanidines, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such guanidines.

Calcium Channel Antagonists And Methodology For Their Identification

View page
US Patent:
53129288, May 17, 1994
Filed:
Feb 11, 1991
Appl. No.:
7/654104
Inventors:
Stanley M. Goldin - Lexington MA
Kazumi Kobayashi - Arlington MA
Andrew G. Knapp - Salem MA
Lee Margolin - Belmont MA
Subbarao Katragadda - Belmont MA
Deborah Daly - Melrose MA
N. Laxma Reddy - Malden MA
Assignee:
Cambridge Neuroscience - Cambridge MA
International Classification:
C07D20920
A61K 31405
US Classification:
548495
Abstract:
A substantially pure compound of the formula: ##STR1## wherein each of R. sub. 1 and R. sub. 2, independently, is H, CH. sub. 3, CF. sub. 3, F, Cl, Br, I, OH, OCH. sub. 3, OCF. sub. 3, SH, SCH. sub. 3, NH. sub. 2, N. sub. 3, NO. sub. 2, CN, COOH, CONH. sub. 2, CH. sub. 2 CONH. sub. 2, or SO. sub. 2 NH. sub. 2 ; R. sub. 3 is H, CH. sub. 3, COOH, CONH. sub. 2, or COOR where R is C. sub. 1-4 alkyl; each R. sub. 4, independently, is H or C. sub. 1-6 alkyl; X is CH. sub. 2, CH. sub. 2 CH. sub. 2, CH. dbd. CH, or CH. sub. 2 CH. sub. 2 CH. sub. 2 ; ##STR2## each Z, independently, is H, CH. sub. 3, or Q where Q is a hydrophobic acyl, benzoyl, phenacetyl, benzyloxycarbonyl, alkoxycarbonyl, or N-methyl-dihydropyridine-3-carbonyl linked to N by an amide bond which is cleavable by an endogenous central nervous system enzyme; D is H or ##STR3## where R. sub. 5 is H or C. sub. 1-4 alkyl; m is an integer from 2 to 12, inclusive; and each n, independently, is an integer from 2 to 12, inclusive; a therapeutic composition including such compound; and a process for identifying calcium channel antagonists.

Acenaphthyl-Substituted Guanidines And Methods Of Use Thereof

View page
US Patent:
56705190, Sep 23, 1997
Filed:
Jun 5, 1995
Appl. No.:
8/463420
Inventors:
Stanley M. Goldin - Lexington MA
Subbarao Katragadda - Belmont MA
N. Laxma Reddy - Malden MA
James B. Fischer - Cambridge MA
Andrew Gannett Knapp - Salem MA
Lee David Margolin - Belmont MA
Assignee:
Cambridge NeuroScience, Inc. - Cambridge MA
International Classification:
A61K 3147
A61K 31395
A61K 3136
A61K 31155
US Classification:
514313
Abstract:
Modulators of neurotransmitter release including substituted guanidines, N"-aminoguanidines, and N,N'N",N"'-tetrasubstituted hydrazinedicarboximidamides, and pharmaceutical compositions thereof are disclosed. Also disclosed are methods involving the use of such neurotransmitter release modulators for the treatment or prevention of pathophysiologic conditions characterized by the release of excessive or inappropriate levels of neurotransmitters. Also disclosed are screening assays for compounds which selectively inhibit glutamate release. Also disclosed are methods of blocking voltage sensitive sodium and calcium channels in mammalian nerve cells.

Therapeutic Guanidines

View page
US Patent:
58470069, Dec 8, 1998
Filed:
May 31, 1995
Appl. No.:
8/454927
Inventors:
Sharad Magar - Somerville MA
Graham J. Durant - Cambridge MA
Stanley M. Goldin - Lexington MA
N. Laxma Reddy - Malden MA
James B. Fischer - Cambridge MA
Subbarao Katragadda - Belmont MA
Andrew Gannett Knapp - Salem MA
Lee David Margolin - Belmont MA
Assignee:
Cambridge NeuroScience, Inc. - Cambridge MA
International Classification:
A01N 3752
C07C27700
US Classification:
514634
Abstract:
The present invention provides N,N'-diaryl substituted guanidines having therapeutic utility. The compounds of the present invention are represented by the formula: ##STR1## wherein R and R. sup. 1 represent hydrogen or other group and Ar and Ar. sup. 1 represent selected aryl groups, and at least one being acenaphthyl.

Substituted Guanidines And Derivatives Thereof As Modulators Of Neurotransmitter Release And Novel Methodology For Identifying Neurotransmitter Release Blockers

View page
US Patent:
57416613, Apr 21, 1998
Filed:
Jun 5, 1995
Appl. No.:
8/463686
Inventors:
Stanley M. Goldin - Lexington MA
Subbarao Katragadda - Belmont MA
N. Laxma Reddy - Malden MA
James B. Fischer - Cambridge MA
Andrew Gannett Knapp - Salem MA
Lee David Margolin - Belmont MA
Assignee:
Cambridge NeuroScience, Inc. - Cambridge MA
International Classification:
C12Q 102
A23J 300
A01N 3752
US Classification:
435 29
Abstract:
Modulators of neurotransmitter release including substituted guanidines, N"-aminoguanidines, and N,N'N",N"'-tetrasubstituted hydrazinedicarboximidamides, and pharmaceutical compositions thereof are disclosed. Also disclosed are methods involving the use of such neurotransmitter release modulators for the treatment or prevention of pathophysiologic conditions characterized by the release of excessive or inappropriate levels of neurotransmitters. Also disclosed are screening assays for compounds which selectively inhibit glutamate release. Also disclosed are methods of blocking voltage sensitive sodium and calcium channels in mammalian nerve cells.

Substituted Aminoguanidines And Methods Of Use Thereof

View page
US Patent:
56773480, Oct 14, 1997
Filed:
Jun 5, 1995
Appl. No.:
8/462834
Inventors:
Stanley M. Goldin - Lexington MA
Subbarao Katragadda - Belmont MA
N. Laxma Reddy - Malden MA
James B. Fischer - Cambridge MA
Andrew Gannett Knapp - Salem MA
Lee David Margolin - Belmont MA
Assignee:
Cambridge NeuroScience, Inc. - Cambridge MA
International Classification:
A61K 31155
US Classification:
514634
Abstract:
Modulators of neurotransmitter release including substituted guanidines, N"-aminoguanidines, and N,N'N",N"'-tetrasubstituted hydrazinedicarboximidamides, and pharmaceutical compositions thereof are disclosed. Also disclosed are methods involving the use of such neurotransmitter release modulators for the treatment or prevention of pathophysiologic conditions characterized by the release of excessive or inappropriate levels of neurotransmitters. Also disclosed are screening assays for compounds which selectively inhibit glutamate release. Also disclosed are methods of blocking voltage sensitive sodium and calcium channels in mammalian nerve cells.
Subbarao A Katragadda from Cambridge, MA, age ~67 Get Report