US Patent:
20110288043, Nov 24, 2011
Inventors:
Lisa Ruderman Chen - Rye NY, US
Simona Skerjanec - Pittstown NJ, US
Dawn Bell - Morristown NJ, US
Steven Steinhubl - Lexington KY, US
International Classification:
A61K 31/7076
A61P 7/02
Abstract:
A method of treating or preventing a disease or condition in a subject that was previously treated with at least one thienopyhdine is described. The method includes administering to the subject an effective amount of at least one reversible, short-acting P2Yi2 inhibitor. The described method can be used for subjects diagnosed with symptoms such as stable or unstable angina, vascular ischemic events, atherosclerosis, acute coronary syndrome, as well as STEMi or N-STEMI. The described method can also be used for patients having previously received a stent, such as a bare metal stent or a drug-eluting stent, and the treatment or prevention of stent thrombosis. The method can be used prior to, during, or after an invasive procedure such as coronary artery bypass grafting, percutaneous coronary intervention, or other genera! surgical procedure.