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Silvia Agron Peter G Perri

from Castro Valley, CA
Age ~62

Silvia Perri Phones & Addresses

  • 18426 Ogilvie Dr, Castro Valley, CA 94546 (510) 928-6672
  • Pleasant Hill, CA
  • San Francisco, CA
  • Del Mar, CA
  • San Diego, CA
  • Encinitas, CA
  • Alameda, CA
  • 18426 Ogilvie Dr #O, Castro Valley, CA 94546 (510) 461-0680

Work

Company: Castro valley high school Aug 1, 2007 Position: Science teacher

Education

Degree: Doctorates, Masters, Doctor of Philosophy School / High School: University of Rome, La Sapienza Specialities: Molecular Biology

Emails

s***i@hotmail.com

Industries

Education Management

Resumes

Resumes

Silvia Perri Photo 1

Science Teacher

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Location:
Castro Valley, CA
Industry:
Education Management
Work:
Castro Valley High School
Science Teacher

Chiron Corporation Oct 1, 1996 - Aug 1, 2004
Scientist

Ucsf Oct 1, 1992 - Sep 1, 1996
Post-Doc Research Fellow
Education:
University of Rome, La Sapienza
Doctorates, Masters, Doctor of Philosophy, Molecular Biology
Chapman University

Publications

Us Patents

Chimeric Alphavirus Replicon Particles

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US Patent:
7531180, May 12, 2009
Filed:
Apr 11, 2002
Appl. No.:
10/123101
Inventors:
John M. Polo - Hayward CA, US
Silvia Perri - Castro Valley CA, US
Kent Thudium - Oakland CA, US
Assignee:
Novartis Vaccines and Diagnostics, Inc - Emeryville CA
International Classification:
A61K 39/12
C12N 7/01
C12N 15/86
A61K 39/193
US Classification:
4241991, 4242181, 424 932, 4352351, 4353201
Abstract:
Chimeric alphaviruses and alphavirus replicon particles are provided including methods of making and using same. Specifically, alphavirus particles are provided having nucleic acid molecules derived from one or more alphaviruses and structural proteins (capsid and/or envelope) from at least two or more alphaviruses. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle, are disclosed.

Chimeric Alphavirus Replicon Particles

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US Patent:
7572453, Aug 11, 2009
Filed:
Apr 3, 2006
Appl. No.:
11/397669
Inventors:
John M. Polo - Danville CA, US
Silvia Perri - Castro Valley CA, US
Kent Thudium - Oakland CA, US
Assignee:
Novartis Vaccines and Diagnostics, Inc. - Emeryville CA
International Classification:
A61K 39/12
A61K 39/193
C12N 7/01
C12N 15/86
US Classification:
4241991, 4242181, 424 932, 4352351, 4353201
Abstract:
Chimeric alphaviruses and replicon particles are provided including methods of making and using same. Specifically, particles are provided having nucleic acid molecules derived from one or more alphaviruses and structural proteins (capsid and/or envelope) from at least two or more alphaviruses. Methods of making, using, and therapeutic preparations containing the chimeric particle, are disclosed.

Enhancement Of The Immune Response For Vaccine And Gene Therapy Applications

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US Patent:
7744900, Jun 29, 2010
Filed:
Apr 29, 2008
Appl. No.:
12/111305
Inventors:
John M Polo - Hayward CA, US
Barbara A Belli - San Diego CA, US
Silvia Perri - Castro Valley CA, US
Timothy C Fong - Moraga CA, US
Assignee:
Novartis Vaccines and Diagnostics, Inc. - Emeryville CA
International Classification:
A61K 39/12
C12P 21/02
C12P 15/00
C07H 21/04
US Classification:
4241991, 4353201, 435 6951, 536 2372
Abstract:
Expression cassettes are provided comprising a promoter operably linked to a nucleic acid molecule which, when transcribed in vivo, forms double-stranded RNA that induces the production of interferon. Expression cassettes also are provided comprising a promoter operably linked to a ribozyme or antisense nucleic acid molecule which, when transcribed in vivo, forms a ribozyme or antisense RNA molecule that stimulates an immune response. In addition, expression cassettes are provided comprising a promoter operably linked to a ribozyme or antisense nucleic acid molecule which, when transcribed in vivo, stimulates apoptosis. Finally, gene delivery vectors are provided which contain such expression cassettes, host cells containing the gene delivery vectors, and methods of utilizing the expression cassettes, gene delivery vectors, and host cells.

Chimeric Alphavirus Replicon Particles

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US Patent:
8158418, Apr 17, 2012
Filed:
Feb 17, 2009
Appl. No.:
12/372295
Inventors:
John Polo - Encinitas CA, US
Silvia Perri - Castro Valley CA, US
Kent Thudium - Oakland CA, US
Assignee:
Novartis Vaccines & Diagnostics Inc. - Emeryville CA
International Classification:
C12N 5/10
C12N 15/86
C12N 15/64
US Classification:
435325, 4352351, 435 691, 435 693, 435456, 4353201
Abstract:
Chimeric alphaviruses and alphavirus replicon particles are provided, including methods of making and using same. Specifically, alphavirus particles are provided having nucleic acid molecules derived from one or more alphaviruses and structural proteins (capsid and/or envelope) from at least two or more alphaviruses. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle, are disclosed.

Alphavirus-Based Vectors For Persistent Infection

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US Patent:
20030170871, Sep 11, 2003
Filed:
Apr 25, 2001
Appl. No.:
09/841994
Inventors:
Thomas Dubensky - Piedmont CA, US
John Polo - Hayward CA, US
Silvia Perri - Castro Valley CA, US
Barbara Belli - San Diego CA, US
Assignee:
CHIRON CORPORATION
International Classification:
A61K048/00
C12P021/02
C12N015/86
C12N005/06
C12N007/00
C07H021/04
A01N063/00
US Classification:
435/235100, 424/093210, 435/325000, 435/456000, 435/069100, 536/023720
Abstract:
Isolated nucleic acid molecules are disclosed, comprising an alphavirus nonstructural protein 2 gene which, when operably incorporated into an alphavirus replicon particle, eukaryotic layered vector initiation system, alphavirus vector construct or RNA vector replicon, provides a noncytopathic phenotype or confers the ability to establish persistent replication. Also disclosed are RNA vector replicons, alphavirus vector constructs, alphavirus replicon particles and eukaryotic layered vector initiation systems which contain the above-identified nucleic acid molecules, as well as methods of using such replicons, constructs, particles and eukaryotic layered vector initiation systems for expression of recombinant proteins.

Chimeric Alphavirus Replicon Particles

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US Patent:
20030232324, Dec 18, 2003
Filed:
Dec 4, 2002
Appl. No.:
10/310734
Inventors:
John Polo - Hayward CA, US
Silvia Perri - Castro Valley CA, US
Kent Thudium - Oakland CA, US
Zequn Tang - San Ramon CA, US
Assignee:
Chiron Corporation
International Classification:
C12Q001/70
C12N007/00
C07H021/04
C12P021/02
C12N015/86
C07H021/02
US Classification:
435/005000, 435/069300, 435/235100, 435/456000, 435/325000, 536/023720
Abstract:
Chimeric alphaviruses and alphavirus replicon particles are provided including methods of making and using same. Specifically, alphavirus particles are provided having nucleic acid molecules derived from one or more alphaviruses and structural proteins (capsid and/or envelope) from at least two or more alphaviruses. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle, are disclosed.

Alphavirus Replicon Packaging Constructs

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US Patent:
20080069804, Mar 20, 2008
Filed:
May 20, 2005
Appl. No.:
11/597452
Inventors:
Zequn Tang - San Ramon CA, US
Silvia Perri - Castro Valley CA, US
John Polo - Danville CA, US
International Classification:
A61K 35/76
C07H 1/00
C07H 21/00
C12N 1/00
C12N 15/63
C12N 7/02
US Classification:
424093600, 435239000, 435243000, 435320100, 536023100, 536055300
Abstract:
Provided herein are modified, functional 5′ amplification sequences that are defective packaging signals. Also provided are compositions and methods comprising these modified 5′ amplification sequences.

Alphavirus Vectors For Respiratory Pathogen Vaccines

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US Patent:
20090104226, Apr 23, 2009
Filed:
May 20, 2005
Appl. No.:
11/597347
Inventors:
Silvia Perri - Castro Valley CA, US
John Polo - Danville CA, US
Yasushi Uematsu - Siena, IT
Catherine Greer - Oakland CA, US
Assignee:
NOVARTIS VACCINES AND DIAGNOSTICS INC. - Emeryville CA
International Classification:
A61K 39/00
US Classification:
4242011, 4242061, 4242041, 4242021
Abstract:
Described herein are compositions and methods for stimulating an immune response to one or more proteins derived from one or more respiratory pathogens. In particular, the invention relates to alphavirus replicons, alphavirus vector constructs, alphavirus replicon particles expressing one or more antigens derived from one or more respiratory pathogens as well as to method of making and using these immunogenic compositions.
Silvia Agron Peter G Perri from Castro Valley, CA, age ~62 Get Report