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Ayyappan K Rajasekaran

from Thornton, PA
Age ~64
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Also known as:
Sigrid A Rajasekaran, Sigrid Langhans Rajasekaran, Sigrid A Langhans, Ak K Rajasekaran, Rajasekaran Sigrid Langhans, Phyllis Stone, Phyllis Rhoten, Phyllis Frame
Related to:
Kevin Saunders, 61Amanda D Stone, 47Randy Stone, 58Tyra Saunders, 29Kristin Stone, 36
Connected to:
Anuradha R Rajasekaran, 48Aruna M Rajasekhar, 57Ashwin Rajasekharan, 46Balaji A Rajasekar, 33Kishore Rajasekar, 35Maya Rajasekharan, 52Pooja Rajasekharan, 34Pradeep S Rajasekaran, 47Rajesh Rajasekar, 49Karthik Rajashekhar, 40

Ayyappan Rajasekaran Phones & Addresses

  • Thornton, PA
  • Chadds Ford, PA
  • 3 Summit Dr, Glen Mills, PA 19342
  • 687 Highpoint Dr, West Chester, PA 19382 (610) 793-1320
  • 3609 Ashwood Ave, Mar Vista, CA 90066 (310) 391-1184
  • Los Angeles, CA
  • New York, NY
  • Chester, PA
  • 3 Summit Dr, Glen Mills, PA 19342 (310) 391-1184

Work

Company: Helen f. graham cancer center 2013 Position: Founder and president

Education

School / High School: UCLA Anderson School of Management 2007

Resumes

Resumes

Ayyappan Rajasekaran Photo 1

Ayyappan Rajasekaran

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Work:
Helen F. Graham Cancer Center

2013 to 2000
Founder and President
Helen F. Graham Cancer Center

2012 to 2000
Senior Research Scientist
Thomas Jefferson University

2008 to 2000
Professor
University of Delaware

2008 to 2000
Adjunct Professor
University of Delaware

2007 to 2000
Affiliated Scientist
Daily and Hematology Times
Washington, DC
2013 to 2013
Basic Research Program
Wilmington, DE
2012 to 2013
Director
A. I. duPont Hospital for Children
Wilmington, DE
2007 to 2012
Director
Article in Wilmington News Journal

Jun 2010 to 2011
Nemours for Congressional Delegation Meeting National EPSCoR
Washington, DC
2010 to 2010
American Cancer Society's India Cancer Initiative

2009 to 2009
Elected Advisory Panel Member
Grief Awareness Coalition

2009 to 2009
Advisory Group Member, Supporting Kidds
Delaware Health Sciences Alliance

2009 to 2009
Panel Member, Stronger Health Based Partnership Conference
Article in Wilmington News Journal
Philadelphia, PA
Jul 2008 to 2009
A. I. duPont Hospital for Children

2008 to 2008
Elected Member, Delaware Health Sciences Alliance Task Force
Delaware Cancer Consortium

2008 to 2008
Elected Member
Philanthropic Funds Raised for the Cancer Center

2007 to 2007
Accelerated Promotion
Los Angeles, CA
2006 to 2007
Associate Professor (Step III
Cellular and Molecular Pathology Graduate Program
Los Angeles, CA
2003 to 2007
Director
Cellular and Molecular Pathology Graduate Program

2006 to 2006
Accelerated promotion to Associate Professor Step III
CURE Digestive Diseases Research Center

2006 to 2006
Elected Member
Cellular and Molecular Pathology Graduate Program
Los Angeles, CA
2004 to 2006
Associate Professor
AAAS Online journal

2005 to 2005
New Development Cancer Research highlighted in the Science SKTE Commentary Article
University of California, Los Angeles (UCLA)
Los Angeles, CA
1997 to 2004
Assistant Professor
Molecular Biology Institute

2003 to 2003
Full Member
Department of Cell Biology and Anatomy
New York, NY
1994 to 1997
Instructor
Indian Institute of Science Fellowship

1983 to 1988

Publications

Us Patents

Endocytotic Pathway Delivery Vehicle For Targeting Drugs And Antibodies To Prostate And Other Tissues

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US Patent:
7776548, Aug 17, 2010
Filed:
Sep 30, 2005
Appl. No.:
11/241416
Inventors:
Ayyappan K. Rajasekaran - Los Angeles CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
G01N 33/53
A61K 39/00
C07K 14/00
US Classification:
435 71, 4241341, 530350
Abstract:
A chimeric transmembrane protein comprising a membrane-spanning polypeptide and an internalization motif of the sequence MXXXL, where X is any amino acid. The chimeric protein can be expressed on the surface of a cell and internalized. Polynucleotides and expression vectors encoding chimeric transmembrane proteins are also provided. Expression of chimeric proteins in the plasma membrane of target cells, followed by binding of antibodies to the chimeric proteins, where the antibodies are conjugated to a cytotoxic agent, provides a means to deliver the cytotoxic agent to the inside of the target cells.

Methods Of Redistributing Apical Target Antigens To Detect And Treat Cellular Proliferative Disease

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US Patent:
20070237712, Oct 11, 2007
Filed:
Jun 14, 2005
Appl. No.:
11/628877
Inventors:
Ayyappan Rajasekaran - Los Angeles CA, US
Jason Christiansen - Los Angeles CA, US
International Classification:
A61K 51/10
A61K 31/407
A61K 31/70
G01N 33/577
A61K 39/395
US Classification:
424001490, 424143100, 424009100, 435007210, 514025000, 514413000, 514042000
Abstract:
Methods of detecting and treating a cellular proliferative in a subject through the use of an antibody and a compound that disrupts the apical trafficking of a target antigen are disclosed. In a one embodiment, the target antigen is PSMA.

Transparent Facial Masks And Other Protective Gear

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US Patent:
20210401080, Dec 30, 2021
Filed:
Jun 28, 2021
Appl. No.:
17/360105
Inventors:
Ayyappan K. RAJASEKARAN - Glen Mills PA, US
International Classification:
A41D 13/11
A41D 31/08
A62B 23/02
Abstract:
Transparent facial masks of regenerated cellulose and other personal protective gear such as gowns, booties, surgical caps, surgical drapes, gloves and eyewear are provided.

Weed Growth Control And Water And Nutrient Conservation Technology

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US Patent:
20210259166, Aug 26, 2021
Filed:
Feb 24, 2021
Appl. No.:
17/183531
Inventors:
Ayyappan K. RAJASEKARAN - Glen Mills PA, US
International Classification:
A01G 13/02
A01G 25/16
A01G 25/02
Abstract:
Weed barrier systems of one or more long lasting weed barrier sheets of flexible polymer or plant material impervious to light and water with precut holes to grow a single to more than 100 plants of different sizes and/or open ended planters which inhibit or prevent weed growth and facilitate root zone targeted water and nutrient delivery are provided.

Kinase Inhibitors

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US Patent:
20170231975, Aug 17, 2017
Filed:
May 1, 2017
Appl. No.:
15/583841
Inventors:
Ayyappan K. Rajasekaran - Glen Mills PA, US
International Classification:
A61K 31/4741
A61K 47/20
A61K 47/40
Abstract:
The disclosed molecules are inhibitors of Bcr-Abl and Src kinases. The molecules are cytotoxic to Gleevec resistant cells. Inhibitors of Bcr-Abl and Src kinases are used in the treatment of Chronic Myelogenous Leukemia among other diseases.

Kinase Inhibitors

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US Patent:
20150140071, May 21, 2015
Filed:
Nov 11, 2014
Appl. No.:
14/537980
Inventors:
Ayyappan K. Rajasekaran - Glen Mills PA, US
International Classification:
A61K 31/4741
A61K 38/16
A61K 47/48
US Classification:
424450, 514291, 424451, 514 193, 424 9373, 514 209, 435375
Abstract:
The disclosed molecules are inhibitors of Bcr-Abl and Src kinases. The molecules are cytotoxic to Gleevec resistant cells. Inhibitors of Bcr-Abl and Src kinases are used in the treatment of Chronic Myelogenous Leukemia among other diseases.
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Ayyappan K Rajasekaran from Thornton, PA, age ~64 Get Report