Shu Chuan Wang

20100266577, Oct 21, 2010

Jul 23, 2008

12/670224

Felipe Samaniego - Houston TX, US
Suizhao Wang - Pearland TX, US
Shu Wang - Houston TX, US

A61K 39/395
A61K 38/00
C07K 14/00
C07K 16/00
C07H 21/04
A61P 35/00

4241301, 514 193, 530350, 5303871, 536 231

In one embodiment, the present invention relates to a method of treating a cancer characterized by inhibition of Fas-mediated apoptosis, comprising administering to a patient suffering from the cancer a pharmaceutically-effective amount of a composition comprising a peptide that competitively antagonizes at least one protein-Fas binding selected from the group consisting of herpes virus 8 protein K1 binding to Fas, CD74 binding to Fas, and pi 00 binding to Fas. In a further embodiment, the peptide is selected from the group consisting of peptides having from about 15 to about 35 amino acid residues and comprising at least a portion of the immunoglobulin domain of K1, peptides having from about 15 to about 35 amino acid residues and comprising at least fifteen consecutive amino acid residues among positions 50-120 of CD74, LVTLLLAGQ ATT A YFL YQQQ, LYQQQGRLDKLTVTSQNLQL, QNLQLENLRMKLPKPPKPVS, and PKPVSKMRMATPLLMQALPM. In another embodiment, the present invention relates to a method of treating a disease characterized by unwanted apoptosis in a mammal, comprising transfecting a cell of the mammal with a nucleic acid molecule encoding CD74. The present invention also relates to the compositions referred to above and their use in manufacture of medicaments for treatment of the diseases described herein.

20120095736, Apr 19, 2012

Oct 12, 2011

13/271455

Shu Wang - Acton MA, US
Yuhua Song - Somervilie MA, US
Chau-Chyun Chen - Lexington MA, US

Aspen Technology, Inc. - Burlington MA

G06G 7/58
G06F 17/10

703 2, 703 12

An extension of COSMO-SAC to electrolytes (eCOSMO-SAC) combines the COSMO-SAC term for short range molecule-molecule, molecule-ion and ion-ion interactions with the extended symmetric Pitzer-Debye-Hückel term for long range ion-ion interactions. The extension recognizes that like-ion repulsion and local electroneutrality govern the surface segment contacts, and introduces a dual sigma profile concept for electrolyte systems. The eCOSMO-SAC formulation predicts activity coefficients of several representative electrolyte systems.

20120186441, Jul 26, 2012

Dec 22, 2011

13/335595

Shu Wang - Shakopee MN, US

F04B 1/32
F16K 11/07

91505, 13762569, 13762564

A pump control system and a torque control valve are disclosed. In one embodiment, the torque control valve includes a sleeve, a spool disposed in the sleeve, and a piston rod disposed through the spool. The spool has a first recess area, a second recess area, and a third recess area. The first and third recess areas each have a port extending into a central bore of the spool. The piston rod includes a groove orifice feature having a spiral groove and is configured such that a fluid flowing from the port in the first recess area to the port in the third recess area must flow through at least a portion of the spiral groove. The fluid flowing through the spiral groove operates to bias the spool in a direction towards the second axial end of the spool.

20220251941, Aug 11, 2022

Feb 9, 2021

17/171181

- Cypress TX, US
Shu Wang - Cypress TX, US
Li Li - Richmond TX, US
Clemente Lopez Arias - Baytown TX, US
Yan Wang - Cypress TX, US
Robert Folkins - Spring TX, US

Quality Drilling Technology, LLC - Cypress TX
Horizontal Drilling Technologies Inc. - Hockley TX

E21B 47/09
E21B 7/04
E21B 4/00

Provided herein is a motor or mud lubricated motor for use with horizontal directional drilling equipment as part of a trenchless drilling system. The motor has a hollow body with proximal and distal open ends and a compartment recessed into a top surface thereof between the proximal open end and the distal open end. A sonde housing with a removable cap secured to the housing is disposed within the compartment and contains a sonde transmitter and a battery operably connected to the sonde transmitter.

20230113164, Apr 13, 2023

Nov 4, 2022

17/980792

Angela L. Holmberg - Somerville MA, US
Kaleigh H. Nicastro - Newark DE, US
Shu Wang - Newark DE, US
Basudeb Saha - Newark DE, US
Li Shuai - Blacksburg VA, US
Dionisios G. Vlachos - Newark DE, US
Melody A. Morris - Elkton MD, US

University of Delaware - Newark DE

C08F 293/00
C07C 69/618
C08G 83/00
C09J 9/02
C09J 7/38
H01M 4/62
C09J 153/00
H01M 10/0565
C07C 67/14
C07C 41/18
C07C 41/38
C09J 133/08
C09J 125/18
B32B 27/30

Disclosed herein is a bio-based copolymer comprising in polymerized form (i) at least one polymerizable bio-based monomer containing one phenolic hydroxyl group which has been derivatized to provide at least one polymerizable functional group which is an ethylenically unsaturated functional group (such as a [meth]acrylate group), where the precursors of the polymerizable bio-based monomers are derived from raw lignin-containing biomass, and (ii) at least one ion-conducting co-monomer other than the bio-based monomer. Also disclosed herein are binders comprising the bio-based copolymer, electrodes comprising the binder, polymer electrolytes comprising the bio-based copolymer and an electrochemical device comprising an electrode in electrical contact with a polymer electrolyte, wherein at least one of the electrode and the polymer electrolyte comprises the bio-based copolymer.

20210340306, Nov 4, 2021

Jun 20, 2019

17/253366

Noriaki YUKIMURA - Tokyo, JP
Michael R. BEAULIEU - Bolton MA, US
Zengquan QIN - Nashville TN, US
Jeffrey M. MAGISTRELLI - Richfield OH, US
Walter A. SALAMANT - Akron OH, US
Ryan J. HUE - Akron OH, US
Shu WANG - Copley OH, US
Laura S. KOCSIS - Copley OH, US
- Chuo-ku, JP

Bridgestone Corporation - Chuo-ku

C08F 293/00
C08C 19/02
C08K 3/36

Embodiments of the present disclosure are directed to functionalized copolymers produced by copolymerization of at least one conjugated diolefin monomer and at least one vinyl monomer, the functionalized copolymer including at least one functional group having silica reactive moieties, wherein the functionalized copolymer has a degree of hydrogenation of 75% to 98 mol % as measured using proton nuclear magnetic resonance spectroscopy (H NMR). In one or more embodiments, the silane modifier may include an oxygen-containing moiety, wherein the oxygen atom of the oxygen-containing moiety may not be directly bonded with the silicon atom.

20200200140, Jun 25, 2020

Dec 19, 2018

16/224988

William P. Attard - Brighton MI, US
Shu Wang - Rochester Hills MI, US
Shuonan Xu - Troy MI, US
Tyler Tutton - Royal Oak MI, US
Srinath Gopinath - Bloomfield Hills MI, US
David A. Lawrence - Lake Orion MI, US

F02P 17/04
F02P 5/15

A calibration system and method for a spark ignition engine of a vehicle involve artificially weighting engine dynamometer data in high engine load regions and using it to generate training data for an artificial neutral network (ANN). A plurality of ANNs are trained using the training data and the plurality of ANNs are then filtered based on their maximum error to obtain a filtered set of trained ANNs. A statistical analysis is performed on each of the filtered set of trained ANNs including determining a set of statistical metrics for each of the filtered set of trained ANNs and then one of the filtered set of trained ANNs having a best combination of error at high engine loads and the set of statistical error metrics is then selected. Finally, an ANN calibration is generated using the selected one of the filtered set of trained ANNs.

20200158038, May 21, 2020

Nov 12, 2019

16/681344

Shu Wang - Rochester Hills MI, US
Ethan E. Bayer - Lake Orion MI, US
William P. Attard - Brighton MI, US
David Lawrence - Lake Orion MI, US

F02D 41/00
F02B 25/14
F01N 3/023
B60W 10/30

Engine low pressure cooled exhaust gas recirculation (LPCEGR) control techniques comprise receiving a measured position of an accelerator pedal and, based on this measurement, detecting a transient tip-out event or a transient tip-in event. In response to detecting the transient tip-out event, an EGR depletion rate is temporarily increased by at least one of (i) downstream throttle valve control to maintain at least a minimum engine airflow or to regulate a rate of decrease of the airflow into the engine, (ii) cylinder bank fuel shutoff, and (iii) pre-scheduled EGR valve control based on the measured accelerator pedal position. In response to detecting the transient tip-in event, an EGR delivery rate is temporarily increased by at least one of (i) the pre-scheduled EGR valve control and (ii) controlling intake/exhaust valves of cylinders of the engine to enable a scavenging mode.