US Patent:
20090215105, Aug 27, 2009
Inventors:
Robert P. Hammer - Baton Rouge LA, US
Steven a. Soper - Baton Rouge LA, US
Serhii Pakhomov - Baton Rouge LA, US
Timothy J. Jensen - Mebane NC, US
Michael W. Allen - Fitchburg WI, US
Irina v. Nesterova - Baton Rouge LA, US
Maria da Graca Henriques Vicente - Baton Rouge LA, US
International Classification:
C12Q 1/02
C07D 487/22
C12P 19/34
Abstract:
Asymmetrically substituted metal-phthalocyanine compounds are disclosed. These compounds and other phthalo-cyanine-derivatives are used in bioimaging, bioanalysis, FRET and quenching techniques, photodynamic therapy, DNA analysis for cells, proteins, tissues and other biological entities, and other applications. Near-infrared fluorescence minimizes matrix effects typically seen in other methods of analyzing biochemical entities in cells, proteins, tissues and other biological entities.