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Robert A Mastico

from Quincy, MA
Deceased

Robert Mastico Phones & Addresses

  • 79 Baxter St, Quincy, MA 02169
  • 29 Woodman Ter, Hanson, MA 02341
  • 200 Pilgrim Rd, Braintree, MA 02184

Professional Records

License Records

Robert A Mastico

Address:
Braintree, MA 02184
License #:
44640 - Expired
Issued Date:
Mar 1, 1965
Expiration Date:
Jun 29, 2004
Type:
Broker

Publications

Us Patents

Antigen-Presenting Capsid With Fusion Ms2-Coat Protein

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US Patent:
55342574, Jul 9, 1996
Filed:
Nov 8, 1993
Appl. No.:
8/090148
Inventors:
Robert A. Mastico - Braintree MA
Peter G. Stockley - Ilkley, GB2
Simon J. Talbot - Street, GB2
Assignee:
British Technology Group Limited
International Classification:
A61K 39116
A61K 3912
C07K 14195
C12N 701
US Classification:
4241921
Abstract:
A chimaeric protein, suitable for incorporation in a vaccine and capable of forming parts of a capsid assembly, comprises the amino acid sequence of the coat protein of phage MS-2, or a conservatively modified variant thereof, or sufficient of said sequence or variant to retain capsid-forming capability, which amino acid sequence has been modified by insertion of a foreign epitope in the region corresponding to a protuberant protein hairpin in the capsid assembly as shown in the crystal structure of the intact phage.

Rna Bacteriophage-Based Delivery System

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US Patent:
61597287, Dec 12, 2000
Filed:
Jan 24, 1995
Appl. No.:
8/360694
Inventors:
Peter George Stockley - Ilkley, GB
Robert Allan Mastico - Braintree MA
Assignee:
BTG International Limited - London
International Classification:
A01N 6300
C12N 700
C12N 701
US Classification:
4353201
Abstract:
A delivery system, especially for delivery to targeted sites in the human or animal body, comprises capsids of the coat protein amino acid sequence of phage MS-2 or related phage, or a modification thereof which retains capsid-forming capability, and at least some of the capsids enclosing a moiety foreign to the genome of MS-2 or related phage.

Capsid Forming And Cystein Modified Chimaeric Ms2-Coat Protein

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US Patent:
56984243, Dec 16, 1997
Filed:
Jan 3, 1995
Appl. No.:
8/167982
Inventors:
Robert Allan Mastico - Braintree MA
Peter George Stockley - Ilkley, GB2
Assignee:
British Technology Group Ltd.
International Classification:
C12N 1511
A61K 3576
US Classification:
4351723
Abstract:
A chimaeric protein is provided, capable of forming part of a capsid assembly and comprising the amino acid sequence of the coat protein of phage MS-2, or a conservatively modified variant thereof, or sufficient of said sequence or variant to retain the capability of forming a capsid assembly, which amino acid sequence has been modified by removal of the cysteine residues present externally of the N-terminal protruberant. beta. -hairpin of the coat protein and insertion of a cysteine residue within the region corresponding to the N-terminal protruberant. beta. -hairpin.

Apparatus For Measuring Impedance To Determine A Property Of A Material

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US Patent:
54500150, Sep 12, 1995
Filed:
Feb 24, 1994
Appl. No.:
8/201514
Inventors:
Robert A. Mastico - Braintree MA
Robert R. Moline - Braintree MA
Assignee:
Forte Technology, Inc. - Norwood MA
International Classification:
G01N 2722
G01R 2726
US Classification:
324665
Abstract:
An impedance measurement system including a series circuit having a reference impedance leg and a measurement leg, the measurement leg including first and second spaced apart electrodes defining a region for receiving a sample of material to be tested; an oscillator circuit connected in parallel with the series circuit and providing a reference voltage and a signal voltage proportioned to the impedance of the measurement leg; and a detector circuit producing an output voltage proportional to changes between the reference voltage and the signal voltage.

Anti-Folr1 Immunoconjugate Dosing Regimens

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US Patent:
20220378694, Dec 1, 2022
Filed:
Apr 14, 2022
Appl. No.:
17/720766
Inventors:
- Waltham MA, US
Robert A. Mastico - Hanson MA, US
James J. O'Leary - Newton MA, US
Olga AB - Millis MA, US
Beni Wolf - Lexington MA, US
Assignee:
ImmunoGen, Inc. - Waltham MA
International Classification:
A61K 9/00
A61K 31/573
C07K 16/28
A61K 47/68
A61K 31/5365
A61K 45/06
Abstract:
Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.

Anti-Folr1 Immunoconjugate Dosing Regimens

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US Patent:
20200046634, Feb 13, 2020
Filed:
Apr 19, 2019
Appl. No.:
16/389396
Inventors:
- Waltham MA, US
Robert A. MASTICO - Hanson MA, US
James J. O'LEARY - Newton MA, US
Olga AB - Millis MA, US
Beni WOLF - Lexington MA, US
Assignee:
ImmunoGen, Inc. - Waltham MA
International Classification:
A61K 9/00
A61K 45/06
A61K 31/5365
C07K 16/28
A61K 31/573
A61K 47/68
Abstract:
Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.

Anti-Folr1 Immunoconjugate Dosing Regimens

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US Patent:
20170239367, Aug 24, 2017
Filed:
Dec 22, 2016
Appl. No.:
15/388873
Inventors:
- Waltham MA, US
Robert A. Mastico - Hanson MA, US
James J. O'Leary - Newton MA, US
Olga Ab - Millis MA, US
Beni Wolf - Lexington MA, US
International Classification:
A61K 47/48
A61K 9/00
A61K 45/06
A61K 31/5365
A61K 31/573
C07K 19/00
Abstract:
Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.

Anti-Folr1 Immunoconjugate Dosing Regimens

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US Patent:
20140363451, Dec 11, 2014
Filed:
May 13, 2014
Appl. No.:
14/276917
Inventors:
- Waltham MA, US
Robert A. Mastico - Hanson MA, US
James J. O'Leary - Newton MA, US
Olga Ab - Millis MA, US
Beni Wolf - Lexington MA, US
Assignee:
ImmunoGen, Inc. - Waltham MA
International Classification:
A61K 47/48
C07K 16/28
A61K 39/395
A61K 31/573
US Classification:
4241781
Abstract:
Methods of administering immunoconjugates that bind to FOLR1 are provided. The methods comprise administering an anti-FOLR1 immunoconjugate to a person in need thereof, for example, a cancer patient, at a therapeutically effective dosing regimen that results in minimal adverse effects.
Robert A Mastico from Quincy, MADeceased Get Report