Inventors:
Mervyn Israel - Germantown TN
Ramakrishnan Seshadri - Germantown TN
Assignee:
The University of Tennessee Research Corporation - Knoxville TN
International Classification:
A61K 3171
C07H 1524
Abstract:
Compounds having the structure ##STR1## in which A is alkanoate having from 4 to 10 carbon atoms, hemiadipate, or hemiglutarate, and R. sub. 1 and R. sub. 2 are n-propyl, or n-butyl, or R. sub. 1 is hydrogen, n-propyl or n-butyl and R. sub. 2 is benzyl, and their corresponding non-toxic pharmacologically acceptable acid salts. The compounds are useful as active agents in therapeutic compositions having antitumor activity.