US Patent:
20200080047, Mar 12, 2020
Inventors:
- Schenectady NY, US
Rachel Marie Gettings - Albany NY, US
Christine Angela Morton - Mechanicville NY, US
Erik Leeming Kvam - Niskayuna NY, US
Jason William Castle - Esperance NY, US
Anindya Kanti De - Bangalore, IN
Jared Timothy Hale - Ballston Lake NY, US
Craig Patrick Galligan - Niskayuna NY, US
Vincent Francis Pizzi - Millis MA, US
International Classification:
C12M 1/00
C12M 1/32
B01D 17/02
B01D 21/02
B01D 21/00
B01L 3/00
B01D 21/24
G01N 30/00
Abstract:
A system for isolating a target molecule from a bioprocess fluid includes a single-use disposable separation device having a plurality of perimeter-bonded layers defining one or more mesofluidic channels of the separation device, wherein each layer includes a biocompatible polymer material, wherein the separation device is configured to separate at least a portion of particles from the bioprocess fluid to generate a substantially clarified bioprocess fluid, and a chromatography system fluidically coupled at the outflow of the separation device in a configuration for further processing the clarified bioprocess fluid.