US Patent:
20030216391, Nov 20, 2003
Inventors:
Derek Lowe - Hamden CT, US
Philip Wickens - Wallingford CT, US
Xin Ma - Bethany CT, US
Mingbao Zhang - Stamford CT, US
William Bullock - Easton CT, US
Philip Coish - New Haven CT, US
Ingo Mugge - New Haven CT, US
Andreas Stolle - Wuppertal, DE
Ming Wang - Milford CT, US
Yamin Wang - Sandy Hook CT, US
Chengzhi Zhang - Orange CT, US
Hai-Jun Zhang - Middletown CT, US
Lei Zhu - Milford CT, US
Manami Tsutsumi - Stratford CT, US
James Livingston - Guilford CT, US
International Classification:
A61K031/5377
A61K031/506
A61K031/497
A61K031/496
A61K031/4439
A61K031/427
C07D417/02
C07D413/02
US Classification:
514/236800, 514/254020, 514/249000, 514/255050, 514/252050, 514/266200, 514/342000, 514/340000, 514/365000, 514/374000, 544/133000, 544/137000, 544/284000, 544/353000, 544/369000, 546/269700, 544/405000, 546/271400, 548/204000, 544/238000, 548/236000
Abstract:
This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.