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Peter R Oeltgen

from Frankfort, KY
Age ~82

Peter Oeltgen Phones & Addresses

  • 326 Clifty Dr, Frankfort, KY 40601 (502) 875-7781 (502) 875-6995
  • 321 Brighton Park Blvd, Frankfort, KY 40601
  • 137 Milwood Dr, Winchester, KY 40391 (859) 744-2192
  • Lexington, KY
  • 137 Milwood Dr, Winchester, KY 40391 (859) 351-9572

Work

Position: Food Preparation and Serving Related Occupations

Education

Degree: Associate degree or higher

Business Records

Name / Title
Company / Classification
Phones & Addresses
Peter Oeltgen
Secretary
Hibernetics, Inc
Noncommercial Research Organization
326 Clifty Dr, Frankfort, KY 40601

Publications

Us Patents

Method For Treating Cytokine Mediated Hepatic Injury

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US Patent:
6380164, Apr 30, 2002
Filed:
Jan 23, 2001
Appl. No.:
09/767657
Inventors:
Peter R. Oeltgen - Winchester KY
Craig J. McClain - Lexington KY
Shirish Barve - Lexington KY
Paul D. Bishop - Fall City WA
Assignee:
University of Kentucky Research Foundation - Lexington KY
ZymoGenetics - Seattle WA
International Classification:
A61K 3808
US Classification:
514 16, 514 2, 514893, 514894, 514937, 530300, 530302
Abstract:
A method of modulating cytokine mediated hepatic injury by administering deltorphins to a mammal. Deltorphin I SEQ ID NO:1, deltorphin II SEQ ID NO:2 or combinations of deltorphins I SEQ ID NO:1 and II SEQ ID NO:2 may be administered. A deltorphin concentration in the range of about 0. 5 mg/kg to about 20 mg/kg in a physiologically acceptable formulation blocks a cytokine cascade in a murine model of septic shock. A therapeutic method of modulating cytokine mediated acute inflammatory, trauma induced and toxin induced hepatic injury, particularly via tumor necrosis factor modulation, is thus disclosed.

Seventeen Amino Acid Peptide (Peptide P) For Treating Ischemia And Reperfusion Injury

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US Patent:
6544950, Apr 8, 2003
Filed:
Dec 6, 2001
Appl. No.:
10/003328
Inventors:
Peter R. Oeltgen - Winchester KY
Mark S. Kindy - Lexington KY
Assignee:
University of Kentucky Research Foundation - Lexington KY
International Classification:
A61K 3800
US Classification:
514 13, 514 2, 514 16, 530300, 530326
Abstract:
Peptide P, having the amino acid sequence Tyr-D-Ala-Phe-Ala-Asp-Val-Ala-Ser-Thr-Ile-Gly-Asp-Phe-Phe-His-Ser-Ile-NH2, is useful to treat ischemia.

Protection Against Ischemia And Reperfusion Injury

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US Patent:
6645938, Nov 11, 2003
Filed:
Jan 10, 2001
Appl. No.:
09/757860
Inventors:
Peter R. Oeltgen - Winchester KY
Paul D. Bishop - Fall City WA
Mark S. Kindy - Lexington KY
Juan A. Sanchez - Lexington KY
Assignee:
ZymoGenetics, Inc. - Seattle WA
University of Kentucky Research Foundation - Lexington KY
International Classification:
A61K 3800
US Classification:
514 13, 530326, 435114, 4242781
Abstract:
A compound and method for using compound-D SEQ ID NO:1 to reduce injury associated with ischemia and reperfusion of mammalian organs such as the heart. The compound may be administered as part of a preconditioning strategy which reduces the extent of injury and improves organ function following cessation and restoration of blood flow. The compound may be used in preparation for planned ischemia or in a prophylactic manner in anticipation of further ischemic events.

Method For Treating Cytokine Mediated Hepatic Injury

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US Patent:
6875742, Apr 5, 2005
Filed:
Oct 5, 2001
Appl. No.:
09/971902
Inventors:
Peter R. Oeltgen - Winchester KY, US
Paul D. Bishop - Fall City WA, US
Craig J. McClain - Lexington KY, US
Shirish Barve - Lexington KY, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
University of Kentucky Research Foundation - Lexington KY
International Classification:
A61K038/10
C07K014/435
US Classification:
514 13, 514 2, 514893, 514894, 514937, 530300, 530302
Abstract:
A method of modulating cytokine mediated hepatic injury by administering compound-D SEQ ID NO:1 to a mammal. A concentration of the compound in the range of about 0. 5 mg/kg to about 20 mg/kg in a physiologically acceptable formulation blocks a cytokine cascade. A therapeutic method of modulating cytokine mediated acute inflammatory, trauma induced and toxin induced hepatic injury, particularly via tumor necrosis factor modulation, is thus disclosed.

Protection Against Ischemia And Reperfusion Injury

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US Patent:
6900178, May 31, 2005
Filed:
Sep 6, 2001
Appl. No.:
09/947656
Inventors:
Peter R. Oeltgen - Winchester KY, US
Paul D. Bishop - Fall City WA, US
Mark S. Kindy - Lexington KY, US
Juan A. Sanchez - Waltham MA, US
Assignee:
University of Kentucky Research Foundation - Lexington KY
International Classification:
A61K038/00
A61K038/08
A61K038/10
US Classification:
514 13, 530326, 530300
Abstract:
A compound and method for using the compound to reduce injury associated with ischemia and reperfusion of mammalian organs such as the heart. The compound, either Deltorphin A and/or Dermorphin H, may be administered as part of a preconditioning strategy which reduces the extent of injury and improves organ function following cessation and restoration of blood flow. The compound may be used in preparation for planned ischemia or in a prophylactic manner in anticipation of further ischemic events.

Seventeen Amino Acid Peptide (Peptide P) For Treating Ischemia And Reperfusion Injury

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US Patent:
6967192, Nov 22, 2005
Filed:
Mar 11, 2003
Appl. No.:
10/384650
Inventors:
Peter R. Oeltgen - Winchester KY, US
Mark S. Kindy - Lexington KY, US
Assignee:
University of Kentucky Research Foundation - Lexington KY
International Classification:
A61K038/00
A61K038/04
US Classification:
514 12, 514 13, 514 16, 514 2, 530300, 530326
Abstract:
Peptide P, having the amino acid sequence Tyr-D-Ala-Phe-Ala-Asp-Val-Ala-Ser-Thr-Ile-Gly-Asp-Phe-His-Ser-Ile-NH2-SEQ ID NO:1, is useful to treat ischemia.

Protection Against Ischemia And Reperfusion Injury

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US Patent:
7060792, Jun 13, 2006
Filed:
May 31, 2005
Appl. No.:
11/141670
Inventors:
Peter R. Oeltgen - Winchester KY, US
Paul D. Bishop - Fall City WA, US
Mark S. Kindy - Lexington KY, US
Juan A. Sanchez - Waltham MA, US
Assignee:
University of Kentucky Research Foundation - Lexington KY
Zymogenetics - Seattle WA
International Classification:
A61K 38/00
US Classification:
530326
Abstract:
A compound and method for using the compound to reduce injury associated with ischemia and reperfusion of mammalian organs such as the heart. The compound, either Deltorphin A and/or Dermorphin H, may be administered as part of a preconditioning strategy which reduces the extent of injury and improves organ function following cessation and restoration of blood flow. The compound may be used in preparation for planned ischemia or in a prophylactic manner in anticipation of further ischemic events.

Method For Treating A Viral Infection Related Or A Chemical Toxin Related Hepatic Injury With Deltorphin D

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US Patent:
7335642, Feb 26, 2008
Filed:
Mar 22, 2005
Appl. No.:
11/085919
Inventors:
Peter R. Oeltgen - Winchester KY, US
Paul D. Bishop - Fall City WA, US
Craig J. McClain - Lexington KY, US
Shirish Barve - Lexington KY, US
Assignee:
University of Kentucky Research Foundation - Lexington NY
International Classification:
A61K 38/10
C07K 14/435
US Classification:
514 13, 514 2, 514893, 514894, 514937, 530300, 530302
Abstract:
A method of modulating cytokine mediated hepatic injury by administering compound-D SEQ ID NO:1 to a mammal. A concentration of the compound in the range of about 0. 5 mg/kg to about 20 mg/kg in a physiologically acceptable formulation blocks a cytokine cascade. A therapeutic method of modulating cytokine mediated acute inflammatory, trauma induced and toxin induced hepatic injury, particularly via tumor necrosis factor modulation, is thus disclosed.
Peter R Oeltgen from Frankfort, KY, age ~82 Get Report