Resumes
Resumes
Peter Gengo Phones & Addresses
-
Basking Ridge, NJ
-
Liberty Corner, NJ
-
Scottsdale, AZ
-
2334 Kyanite Pl, Carlsbad, CA 92009 (760) 918-9234
-
6769 Obsidian Pl, Carlsbad, CA 92009 (760) 918-9234
-
12117 Warwickshire Park, Raleigh, NC 27613 (919) 848-4403
-
Morgan Hill, CA
-
Sunnyvale, CA
-
San Diego, CA
-
Santa Clara, CA
Publications
Us Patents
Cardioprotective Delta Opioid Receptor Agonists And Methods Of Using Same
View pageUS Patent:
7314880, Jan 1, 2008
Filed:
Dec 31, 2003
Appl. No.:
10/749437
Inventors:
William Pendergast - Durham NC, US
Peter J. Gengo - Sunnyvale CA, US
Xin Ma - Carrboro NC, US
Peter J. Gengo - Sunnyvale CA, US
Xin Ma - Carrboro NC, US
Assignee:
Mount Cook Biosciences, Inc. - New York NY
International Classification:
A61K 31/495
A61K 31/517
A61K 31/496
A61K 31/517
A61K 31/496
US Classification:
51425504, 5142664, 51425301
Abstract:
The present invention relates to compositions and methods of treatment for cardioprotection through the use of non-peptidic delta opioid receptor agonist compound(s) that mediate cardioprotective effects of ischemic preconditioning. The compounds are used to reduce injury associated with ischemia and reperfusion of cardiac tissue. Further, the compounds may be used in solutions preserving the viability of an isolated organ.
Compositions And Methods For Combating Lower Urinary Tract Dysfunctions With Delta Opioid Receptor Agonists
View pageUS Patent:
8476280, Jul 2, 2013
Filed:
May 8, 2003
Appl. No.:
10/434004
Inventors:
Peter J. Gengo - Raleigh NC, US
Kestutis P. Biciunas - Durnam NC, US
Xin Ma - Carrboro NC, US
William Pendergast - Durham NC, US
Shyi-Tai Jan - Cary NC, US
Kestutis P. Biciunas - Durnam NC, US
Xin Ma - Carrboro NC, US
William Pendergast - Durham NC, US
Shyi-Tai Jan - Cary NC, US
Assignee:
Versi Group, LLC - Gladstone NJ
International Classification:
A61K 31/4965
A61K 31/497
A61K 31/497
US Classification:
51425504, 51425212, 51425301, 514730
Abstract:
Compositions and methods for treatment of a urinary tract dysfunction by administering to a subject in need of such treatment a pharmaceutical composition including a delta opioid receptor agonist in an amount effective to reduce the effects of the urinary tract dysfunction. The compositions may further include an additional active agent that is used to treat urinary tract dysfunctions, e. g. , alpha-adrenergic agonists, anticholinergics, alpha-adrenergic antagonists and tricyclic antidepressants.
Method Of Treating Depression With Delta Receptor Agonist Compounds
View pageUS Patent:
20030144299, Jul 31, 2003
Filed:
Oct 29, 2002
Appl. No.:
10/282411
Inventors:
William Pendergast - Durham NC, US
Peter Gengo - Raleigh NC, US
Peter Gengo - Raleigh NC, US
International Classification:
A61K031/495
US Classification:
514/255040
Abstract:
Compositions and methods for treatment of depression or other affective mood disorders or pathological mental and/or emotional states, by administration to a subject suffering or susceptible to same, of therapeutically effective delta receptor agonist compound(s), optionally in combination with other mood disorder-combating agents.
Cardioprotective Delta Opioid Receptor Agonists And Methods Of Using Same
View pageUS Patent:
20080125443, May 29, 2008
Filed:
Nov 27, 2007
Appl. No.:
11/945815
Inventors:
William Pendergast - Durham NC, US
Peter J. Gengo - Sunnyvale CA, US
Xin Ma - Carrboro NC, US
Peter J. Gengo - Sunnyvale CA, US
Xin Ma - Carrboro NC, US
International Classification:
A61K 31/495
US Classification:
51425504
Abstract:
The present invention relates to compositions and methods of treatment for cardioprotection through the use of non-peptidic delta opioid receptor agonist compound(s) that mediate cardioprotective effects of ischemic preconditioning. The compounds are used to reduce injury associated with ischemia and reperfusion of cardiac tissue. Further, the compounds may be used in solutions preserving the viability of an isolated organ.
Crhr2 Peptide Agonists And Uses Thereof
View pageUS Patent:
20100130424, May 27, 2010
Filed:
Nov 4, 2009
Appl. No.:
12/612548
Inventors:
RONALD V. SWANSON - DEL MAR CA, US
NIGEL P. SHANKLEY - SOLANA BEACH CA, US
VERONICA MORENO - SAN DIEGO CA, US
PETER GENGO - Carlsbad CA, US
NIGEL P. SHANKLEY - SOLANA BEACH CA, US
VERONICA MORENO - SAN DIEGO CA, US
PETER GENGO - Carlsbad CA, US
International Classification:
A61K 38/16
C07K 14/00
C07H 21/00
C07K 16/00
A61P 3/10
A61P 9/00
C07K 14/00
C07H 21/00
C07K 16/00
A61P 3/10
A61P 9/00
US Classification:
514 12, 530324, 536 231, 5303879
Abstract:
The present invention relates to novel peptides that are selective corticotrophin releasing hormone receptor type 2 (CRHR2) agonists and compositions thereof for the treatment, amelioration or inhibition of cardiovascular conditions, including but not limited to heart failure. The novel peptide agonist preferably comprise modifications that include pegylated peptides. Furthermore, the present invention also relates to methods for the treatment and prevention of a disease or disorder related to CRHR2 activity.
Method For Treating Heart Failure With Stresscopin-Like Peptides
View pageUS Patent:
20110105397, May 5, 2011
Filed:
Nov 4, 2010
Appl. No.:
12/940019
Inventors:
Peter J. Gengo - Carlsbad CA, US
Hani N. Sabbah - Waterford MI, US
Nigel P. Shankley - Solana Beach CA, US
Hani N. Sabbah - Waterford MI, US
Nigel P. Shankley - Solana Beach CA, US
International Classification:
A61K 38/22
A61P 9/04
A61P 9/04
US Classification:
514 97
Abstract:
The present invention relates to novel methods of treating heart failure comprising administering an amount of stresscopin-like peptide to a subject in need thereof; and substantially maintaining the amount of said peptide present in the plasma of said subject at a concentration resulting in a therapeutic benefit without a substantial increase in the heart rate of said subject. The method involves the use of stresscopin-like peptides that are selective corticotrophin releasing hormone receptor type 2 (CRHR2) agonists.