Resumes
Resumes
Paul Keall
View pageLocation:
United States
Paul Keall Phones & Addresses
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1300 Oak Creek Dr, Palo Alto, CA 94304
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Stanford, CA
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3111 Stuart Ave, Richmond, VA 23221
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3136 Hanover Ave, Richmond, VA 23221
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2623 Kensington Ave, Richmond, VA 23220
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2300 Grace St, Richmond, VA 23220
Business Records
Name / Title
Company / Classification
Phones & Addresses
Professor
Virginia Commonwealth University
College/University · Ret Drugs/Sundries
College/University · Ret Drugs/Sundries
410 N 12 St, Richmond, VA 23298
PO Box 980533, Richmond, VA 23298
(804) 828-8350, (804) 828-3000
PO Box 980533, Richmond, VA 23298
(804) 828-8350, (804) 828-3000
Publications
Us Patents
Method And System For Using Computed Tomography To Test Pulmonary Function
View pageUS Patent:
7668357, Feb 23, 2010
Filed:
Oct 17, 2005
Appl. No.:
11/250627
Inventors:
Paul John Keall - Richmond VA, US
Sarang C. Joshi - Chapel Hill NC, US
Sarang C. Joshi - Chapel Hill NC, US
Assignee:
Stanford University - Palo Alto CA
International Classification:
G06K 9/00
US Classification:
382130, 382128, 382131
Abstract:
Computed axial tomography images of different respiratory phases of lungs are obtained, where the intensity of the image measures lung density. One image is deformed to the coordinate space of the other image, and the differences between the intensity values of the other image as compared to the mapped image are evaluated as measures of ventilation.
Method And System For Four Dimensional Intensity Modulated Radiation Therapy For Motion Compensated Treatments
View pageUS Patent:
7835493, Nov 16, 2010
Filed:
Aug 6, 2008
Appl. No.:
12/187222
Inventors:
Paul J. Keall - Stanford CA, US
Yelin Suh - Palo Alto CA, US
Elisabeth Weiss - Williamsburg VA, US
Yelin Suh - Palo Alto CA, US
Elisabeth Weiss - Williamsburg VA, US
Assignee:
Stanford University - Palo Alto CA
International Classification:
A61N 5/10
H05G 1/08
H05G 1/08
US Classification:
378 65, 378 95
Abstract:
A deliverable four dimensional (4D) intensity modulated radiation therapy (IMRT) planning method is disclosed, for delivery using a linear accelerator with a dynamic multi-leaf collimator (DMLC). A 4D computed tomography (CT) scan is used for segmenting tumor anatomy on a reference phase of periodic motion of the tumor. Deformable registration of the 4D CT data is used to generate corresponding anatomical structures on other phases. Preferably, the collimator for each beam position is aligned using the gross tumor volume (GTV) centroid motion corresponding to the periodic motion of the tumor, as determined from the two dimensional (2D) projection of a given beam position. A deliverable IMRT plan is created on the 4D CT image set in which the MLC leaf positions and beam on/off status can vary as a function of respiratory phase by solving a four dimensional optimization problem. The mechanical constraints of the MLC leaves are included in the optimization.
System And Method For Using Prospective Evaluation Of Displacement And Velocity Of A Respiratory Trace In A Five Dimensional Parameter Space To Reduce Artifacts And Dosage In Four Dimensional Computed Tomography
View pageUS Patent:
7894571, Feb 22, 2011
Filed:
May 8, 2009
Appl. No.:
12/463377
Inventors:
Paul J. Keall - Stanford CA, US
Ulrich W. Langner - Lexington KY, US
Ulrich W. Langner - Lexington KY, US
Assignee:
Stanford University - Palo Alto CA
International Classification:
G01N 23/00
US Classification:
378 8, 378 4
Abstract:
A displacement and velocity based prospective cine CT (PDV CT) method is disclosed for starting image acquisition if the displacement and velocity are simultaneously within predetermined tolerances, thus essentially sorting 2D CT images in a five dimensional parameter space, where displacement and the sign of the velocity are used for the temporal sorting, replacing the use of either phase or displacement as the temporal parameter during retrospective sorting, with velocity as a separate parameter correlating to some parameter of the system, e. g. the airflow rate, making it possible to do the image sorting in real-time.
Method And Apparatus For Respiratory Audio-Visual Biofeedback For Imaging And Radiotherapy
View pageUS Patent:
7955270, Jun 7, 2011
Filed:
Oct 4, 2006
Appl. No.:
11/538548
Inventors:
Paul Keall - Stanford CA, US
Rohini George - Richmond VA, US
Radhe Mohan - Pearland TX, US
Keith Miller - Fort Myers FL, US
Theodore Chung - Richmond VA, US
Rohini George - Richmond VA, US
Radhe Mohan - Pearland TX, US
Keith Miller - Fort Myers FL, US
Theodore Chung - Richmond VA, US
Assignee:
Stanford University - Palo Alto CA
International Classification:
A61B 5/08
US Classification:
600534, 600411
Abstract:
An improved method and apparatus for respiratory audio-visual biofeedback are disclosed. A guide patterned after a breathing cycle comfortable to the patient serves as a target. The target is displayed as a bar moving vertically upward during inhale and vertically downward during exhale, between fixed end ex-hale and end in-hale limits. The patient's current respiratory position is also displayed as a bar, oriented parallel to the target bar so that the difference between the current position and the target position is easy for the patient to see.
Configurations For Integrated Mri-Linear Accelerators
View pageUS Patent:
8331531, Dec 11, 2012
Filed:
Mar 15, 2010
Appl. No.:
12/661303
Inventors:
Rebecca Fahrig - Palo Alto CA, US
Norbert J. Pelc - Los Altos CA, US
Kim Pauly - Stanford CA, US
Greig C. Scott - Palo Alto CA, US
Amit Sawant - Mountain View CA, US
Paul J. Keall - Palo Alto CA, US
Lei Xing - Palo Alto CA, US
Steven M. Conolly - Palo Alto CA, US
Norbert J. Pelc - Los Altos CA, US
Kim Pauly - Stanford CA, US
Greig C. Scott - Palo Alto CA, US
Amit Sawant - Mountain View CA, US
Paul J. Keall - Palo Alto CA, US
Lei Xing - Palo Alto CA, US
Steven M. Conolly - Palo Alto CA, US
Assignee:
The Board of Trustees of the Leland Stanford Junior University - Palo Alto CA
The Regents of the University of California - Berkeley CA
The Regents of the University of California - Berkeley CA
International Classification:
A61N 5/10
G01N 23/04
G01N 23/04
US Classification:
378 65, 378 63
Abstract:
The present invention provides a radiotherapy treatment apparatus that includes a treatment beam, a magnetic field disposed parallel collinear to the treatment beam, and a target that is disposed along the treatment beam. The treatment beam can be a charged particle beam, a proton beam, an electron beam, or a linear accelerator (Linac) beam. The magnetic field is from a magnetic resonance imager (MRI), a megavolt x-ray imager, or a kilovolt x-ray imager and is disposed to operate in coordination with operation of the treatment beam and to narrow the beam. The tumor is disposed to rotate with respect to the treatment beam and the magnetic field, or the treatment beam and the magnetic field are disposed to rotate up to 360 with respect to the target when mounted to a ring gantry. The apparatus can include a rotation angle dependent shim disposed to account for Earth's magnetic field.
Method And System For Four Dimensional Intensity Modulated Radiation Therapy For Motion Compensated Treatments
View pageUS Patent:
8340247, Dec 25, 2012
Filed:
Nov 16, 2010
Appl. No.:
12/947643
Inventors:
Paul J. Keall - Stanford CA, US
Yelin Suh - Palo Alto CA, US
Elisabeth Weiss - Williamsburg VA, US
Yelin Suh - Palo Alto CA, US
Elisabeth Weiss - Williamsburg VA, US
Assignee:
Stanford University - Palo Alto CA
International Classification:
A61N 5/10
G21K 5/10
H05G 1/08
G21K 5/10
H05G 1/08
US Classification:
378 69, 378 65, 378 95
Abstract:
A deliverable four dimensional (4D) intensity modulated radiation therapy (IMRT) planning method is disclosed, for delivery using a linear accelerator with a dynamic multi-leaf collimator (DMLC). A 4D computed tomography (CT) scan is used for segmenting tumor anatomy on a reference phase of periodic motion of the tumor. Deformable registration of the 4D CT data is used to generate corresponding anatomical structures on other phases. Preferably, the collimator for each beam position is aligned using the gross tumor volume (GTV) centroid motion corresponding to the periodic motion of the tumor, as determined from the two dimensional (2D) projection of a given beam position. A deliverable IMRT plan is created on the 4D CT image set in which the MLC leaf positions and beam on/off status can vary as a function of respiratory phase by solving a four dimensional optimization problem. The mechanical constraints of the MLC leaves are included in the optimization.
Method And System Of Adaptive Control For Reducing Motion Artifacts And Patient Dose In Four Dimensional Computed Tomography
View pageUS Patent:
8457717, Jun 4, 2013
Filed:
Apr 7, 2005
Appl. No.:
10/599084
Inventors:
Paul J. Keall - Richmond VA, US
Jeffrey F. Williamson - Richmond VA, US
Jeffrey F. Williamson - Richmond VA, US
Assignee:
Stanford University - Palo Alto CA
International Classification:
A61B 5/055
H04B 15/00
G21K 5/00
H04B 15/00
G21K 5/00
US Classification:
600425, 702189, 378 64
Abstract:
Motion artifacts and patient dose during 4D CT imaging are reduced by adaptive control of data acquisition. The respiration signal () and CT data acquisition () are linked, such that ‘bad’ data from erratic breathing cycles that cause artifacts is not acquired by pausing CT data acquisition () when erratic breathing is detected, and not resuming CT data acquisition until steady-state respiration is resumed. Training data is used to develop a tolerance envelope for a respiratory signal such that for erratic breathing cycles the respiratory signal is not within the tolerance envelope ().
Method To Track Three-Dimensional Target Motion With A Dynamical Multi-Leaf Collimator
View pageUS Patent:
20080159478, Jul 3, 2008
Filed:
Dec 11, 2007
Appl. No.:
12/001762
Inventors:
Paul J. Keall - Stanford CA, US
Amit Sawant - Los Altos CA, US
Yelin Suh - Stanford CA, US
Sergey Povzner - Burlingame CA, US
Herbert Cattell - Mountain View CA, US
Amit Sawant - Los Altos CA, US
Yelin Suh - Stanford CA, US
Sergey Povzner - Burlingame CA, US
Herbert Cattell - Mountain View CA, US
International Classification:
A61N 5/10
US Classification:
378 65
Abstract:
A method of continuous real-time monitoring and positioning of multi-leaf collimators during on and off radiation exposure conditions of radiation therapy to account for target motion relative to a radiation beam is provided. A prediction algorithm estimates future positions of a target relative to the radiation source. Target geometry and orientation are determined relative to the radiation source. Target, treatment plan, and leaf width data, and temporal interpolations of radiation doses are sent to the controller. Coordinates having an origin at an isocenter of the isocentric plane establish initial aperture end positions of the leaves that is provided to the controller, where motors to position the MLC midpoint aperture ends according to the position and target information. Each aperture end intersects a single point of a convolution of the target and the isocenter of the isocentric plane. Radiation source hold-conditions are provided according to predetermined undesirable operational and/or treatment states.