Inventors:
Alexander R. Neurath - New York NY
Nathan Strick - Oceanside NY
Paul Haberfield - Brooklyn NY
Shibo Jiang - New York NY
International Classification:
G01N 33545
Abstract:
A method for the rapid screening of a drug targeted to the V3 hypervariable loop of the human immunodeficiency virus type 1 or type 2 envelope glycoprotein gp 120 comprising measuring the inhibitory effect of the drug on the interaction between gp 120 (or an antigen comprising the V3 hypervariable loop of HIV 1 gp 120 or HIV 2 gp 120) and antibodies specific for the V3 hypervariable loop, and anti-HIV chemotherapy with drugs binding to the V3 hypervariable loop.