Inventors:
Annmarie Louise Sabb - Pennington NJ
Robert Lewis Vogel - Stratford NJ
Madelene Miyoko Antane - West Windsor NJ
Panolil Raveendranath - Monroe NY
Sreenivasulu Megati - New City NY
Michael David Smith - Martinez CA
James Albert Nelson - Washington Crossing PA
International Classification:
A61K 3155
Abstract:
This invention provides processes for synthesizing compounds of formula I: wherein R is H or alkyl; R , R are H, alkyl, alkoxy, halogen, fluorinated alkyl, âCN, alkyl sulfonamide, alkyl amide, amino, alkylamino, dialkylamino, fluorinated alkoxy, acyl, or aroyl; R and R are H, alkyl or cycloalkyl; the dashed line indicates an optional double bond; as well as intermediates and pharmaceutically acceptable salts thereof.