Search

Nasri Badran Phones & Addresses

  • 428 Oxford Rd, New Rochelle, NY 10804 (914) 636-4214 (914) 636-2134
  • Wykagyl, NY

Publications

Us Patents

Microcrystalline 3-(Alpha-Acetonylbenzyl)-4-Hydroxycoumarin (Warfarin) And Methods Of Making

View page
US Patent:
41137442, Sep 12, 1978
Filed:
Aug 13, 1974
Appl. No.:
5/496932
Inventors:
Nasri W. Badran - New Rochelle NY
International Classification:
C07D31120
US Classification:
26034344
Abstract:
Microcrystalline 3-(alpha-acetonylbenzyl)-4-hydroxy coumarin (warfarin), having a crystal size not greater than 4. 0 microns, is stable for long periods of time, is advantageous in that it is rapidly absorbed from the gastrointestinal tract and thus provides a highly desirable level of bioavailability not previously possible. It is crystallized from a buffered alkaline solution of warfarin by acidification thereof. Compositions thereof are useful for anticoagulant and rodenticide purposes, and methods of making such compositions and of using the new microcrystalline form of warfarin for such purposes are disclosed.
Nasri W Badran from New Rochelle, NYDeceased Get Report