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Moran Bercovici Phones & Addresses

  • San Jose, CA
  • Santa Clara, CA
  • Stanford, CA

Publications

Us Patents

Non-Focusing Tracers For Indirect Detection In Electrophoretic Displacement Techniques

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US Patent:
20110220499, Sep 15, 2011
Filed:
Mar 14, 2011
Appl. No.:
13/065168
Inventors:
Robert D. Chambers - Enfield NH, US
Juan G. Santiago - Stanford CA, US
Moran Bercovici - Santa Clara CA, US
International Classification:
G01N 27/447
US Classification:
204451, 204549, 204548
Abstract:
A novel method for visualizing electrokinetic process zones (e.g., for isotachophoresis (ITP)) is provided. We introduce negligibly small concentrations of a fluorophore that is not focused by isotachophoresis. This non-focusing tracer (NFT) migrates through multiple isotachophoresis zones. As it enters each zone, the NFT concentration adapts to the local electric field in each zone. ITP zones can then be visualized with a point detector or camera. The method can be used to detect, identify, and quantify unknown analyte zones, and can visualize complex and even transient electrophoresis processes. This visualization technique is particularly suited to microfluidic and lab-on-a-chip applications, as typical fluorescence microscopes and CCD cameras can provide high-resolution spatiotemporal data.

Fluorescent Finger Prints For Indirect Detection In Isotachophoresis

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US Patent:
20120152746, Jun 21, 2012
Filed:
May 31, 2011
Appl. No.:
13/134165
Inventors:
Juan G. Santiago - Stanford CA, US
Moran Bercovici - Santa Clara CA, US
Govind V. Kaigala - Horgen, CH
Robert D. Chambers - Enfield NH, US
International Classification:
G01N 27/447
B01D 57/02
US Classification:
204549
Abstract:
Indirect detection and/or identification of analytes by ITP can be enhanced by adding a mixture of labeled carrier ampholytes (CAs) to the sample to provide a continuous range of mobility markers. Each analyte can be detected and quantified by corresponding gaps in the CA signal. This approach does not require a priori choice of fluorophores and can be readily applied (without extensive and specific design) to a wide range of analytes. Analyte identification can be expedited by computing a normalized signal integral (NSI) from the CA signals. Empirical calibrations can relate the NSI to effective mobility. Effective mobility results under two or more different pH conditions can be used to determine analyte pKa and fully ionized mobility, which are analyte properties that can facilitate analyte identification.
Moran Bercovici from San Jose, CA, age ~42 Get Report